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ARG2 Products

(Arginase, Type II (ARG2))

Categories

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood\; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008].

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Featured ARG2 Categories

ARG2 Antibodies

High quality antibodies with extensive validation data.

ARG2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ARG2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ARG2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IP, WB
Validations
  • (4)
Cat. No. ABIN7144586
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (2)
  • (3)
Cat. No. ABIN2855753
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ICC, IHC, WB
Validations
  • (3)
Cat. No. ABIN1077838
Quantity 100 μL
Datasheet Datasheet

Recommended ARG2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6973928
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6999578
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953914
Quantity 96 tests
Datasheet Datasheet

Recommended ARG2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN2714866
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089150
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131286
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ARG2 products

Polis, Srikanth, Gurevich, Gil-Henn, Samson: "L-Norvaline, a new therapeutic agent against Alzheimer's disease." in: Neural regeneration research, Vol. 14, Issue 9, pp. 1562-1572, (2019) (PubMed).

Polis, Srikanth, Elliott, Gil-Henn, Samson: "L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 4, pp. 1036-1054, (2019) (PubMed).

Isik, Bas, Demirel, Kavurt, Aydemir, Kavurt, Cetin: "Increased asymmetric dimethylarginine levels in severe transient tachypnea of the newborn." in: Journal of perinatology : official journal of the California Perinatal Association, Vol. 36, Issue 6, pp. 459-62, (2018) (PubMed).

Tanaka, Kumasawa, Kakigano, Mimura, Endo, Tomimatsu, Kimura: "Arginase controls soluble vascular endothelial growth factor receptor 1 (sFlt1) to maintain pregnancy homeostasis." in: Biochemical and biophysical research communications, Vol. 499, Issue 2, pp. 150-155, (2018) (PubMed).

Gonon, Jung, Katz, Westerblad, Shemyakin, Sjöquist, Lundberg, Pernow: "Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production." in: PLoS ONE, Vol. 7, Issue 7, pp. e42038, (2012) (PubMed).

Shemyakin, Kövamees, Rafnsson, Böhm, Svenarud, Settergren, Jung, Pernow: "Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus." in: Circulation, Vol. 126, Issue 25, pp. 2943-50, (2012) (PubMed).

Lukasova, Malaval, Gille, Kero, Offermanns: "Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells." in: The Journal of clinical investigation, Vol. 121, Issue 3, pp. 1163-73, (2011) (PubMed).

Grönros, Jung, Lundberg, Cerrato, Ostenson, Pernow: "Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats." in: American journal of physiology. Heart and circulatory physiology, Vol. 300, Issue 4, pp. H1174-81, (2011) (PubMed).

Kryl, Yacoubian, Haapasalo, Castren, Lo, Barker: "Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 14, pp. 5823-33, (1999) (PubMed).

Gomeza, Joly, Kuhn, Knöpfel, Bockaert, Pin: "The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins." in: The Journal of biological chemistry, Vol. 271, Issue 4, pp. 2199-205, (1996) (PubMed).

Synonyms and alternative names related to ARG2

arginase 2 (arg2), arginase 2 (ARG2), arginase 2 (Arg2), arginase type II (Arg2), AII, arg1, ARG2, arg3, AU022422, LeARG2, wu:fb67g02, zgc:65793, zgc:85630

Protein level used designations for ARG2

  • arginase-2, mitochondrial
  • arginase, type II
  • arginase 2
  • ureohydrolase
  • arginase, non-hepatic 1
  • arginase, non-hepatic 3
  • arginase, type 2
  • non-hepatic arginase
  • arginase-2, mitochondrial-like
  • L-arginine amidinohydrolase
  • L-arginine ureahydrolase
  • kidney arginase
  • kidney-type arginase
  • nonhepatic arginase
  • type II arginase
  • AII type II arginase
  • arginase II
  • arginase type II
  • mitochondrial arginase 2
  • mitochondrial arginase type II
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