Recommendations are based on data provided indicating:
ELISA Kit Sensitivity
The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
ELISA Kit Specificity
The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
ELISA Kit Robustness
The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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STAU1 Antigen Profile
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
Alternative names and synonyms associated with STAU1
staufen double-stranded RNA binding protein 1 (STAU1) ELISA Kit
staufen (stau) ELISA Kit
staufen double-stranded RNA binding protein 1 (stau1) ELISA Kit