AVPR2 Proteins

2 Arginine Vasopressin Receptor 2 (AVPR2) Proteins from 2 manufacturers are available on www.antibodies-online.com.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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2 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3075338
$7,294.44
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityMouse (Murine)
Application SDS, WB
Order details Cat. No. ABIN6377843
$1,744.65
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
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AVPR2 Protein Profile

Protein Summary

This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing.

Alternative names and synonyms associated with AVPR2

  • arginine vasopressin receptor 2 (AVPR2) antibody
  • arginine vasopressin receptor 2 (Avpr2) antibody
  • ADHR antibody
  • AVPR2 antibody
  • DI1 antibody
  • DIR antibody
  • DIR3 antibody
  • ND1 antibody
  • NDI antibody
  • V2R antibody
  • VPV2R antibody

Protein level used designations for AVPR2

vasopressin V2 receptor , arginine vasopressin receptor 2 , AVPR V2 , antidiuretic hormone receptor , renal-type arginine vasopressin receptor , V-2 lysine vasopressin receptor , V2R , arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) , nephrogenic diabetes insipidus , Vasopressin receptor V2

GENE ID SPECIES
100528011 Ovis aries
697763 Macaca mulatta
100137253 Papio anubis
100328747 Oryctolagus cuniculus
100595937 Nomascus leucogenys
554 Homo sapiens
397462 Sus scrofa
281642 Bos taurus
12000 Mus musculus
25108 Rattus norvegicus
403804 Canis lupus familiaris
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