AVPR2 Proteins
2 Arginine Vasopressin Receptor 2 (AVPR2) Proteins from 2 manufacturers are available on www.antibodies-online.com.
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Arginine Vasopressin Receptor 2 (AVPR2) (AA 1-371) protein (rho-1D4 tag) Protein
Arginine Vasopressin Receptor 2 (AVPR2) Protein Protein
AVPR2 Protein Profile
Protein Summary
This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing.
Alternative names and synonyms associated with AVPR2
- arginine vasopressin receptor 2 (AVPR2) antibody
- arginine vasopressin receptor 2 (Avpr2) antibody
- ADHR antibody
- AVPR2 antibody
- DI1 antibody
- DIR antibody
- DIR3 antibody
- ND1 antibody
- NDI antibody
- V2R antibody
- VPV2R antibody
Protein level used designations for AVPR2
vasopressin V2 receptor , arginine vasopressin receptor 2 , AVPR V2 , antidiuretic hormone receptor , renal-type arginine vasopressin receptor , V-2 lysine vasopressin receptor , V2R , arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) , nephrogenic diabetes insipidus , Vasopressin receptor V2
GENE ID | SPECIES |
---|---|
100528011 | Ovis aries |
697763 | Macaca mulatta |
100137253 | Papio anubis |
100328747 | Oryctolagus cuniculus |
100595937 | Nomascus leucogenys |
554 | Homo sapiens |
397462 | Sus scrofa |
281642 | Bos taurus |
12000 | Mus musculus |
25108 | Rattus norvegicus |
403804 | Canis lupus familiaris |
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