Browse our anti-CAP1 (CAP1) Antibodies

Human CAP, Adenylate Cyclase-Associated Protein 1 (Yeast) (CAP1) interaction partners

1. It identified CAP1 as a negative regulator of milk synthesis and proliferation of bovine mammary epithelial cells.

2. Using multiple -omics approach, study validated key molecules, such as CAP1, SHC1 and PRCP, that might play a significant role in IgA nephropathy pathogenesis.

3. findings indicate that CAP1 is a geranylgeranyl-binding partner of Rap1

4. RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk

5. Significant up-regulation of PBMCs CAP1, CD36 mRNA and plasma resistin found in significant coronary artery disease, as well as in nonsignificant coronary artery disease compared to control group, indicates that resistin could be able to exert its effects stronger on cells with up-regulated CAP1 mRNA thus contributing atherosclerosis development.

6. REVIEW: summarizes information available to date about the structural organization, regulation of functional activity of adenylyl cyclase-associated protein 1 (CAP1), and its participation in cellular processes

7. Results identify a role for CAP1 in regulating proliferative transformation of cancer cells, with ERK signaling playing pivotal roles in mediating both cell functions.

8. CAP1 expression is markedly increased in human glioma and that downregulation of CAP1 in tumors may serve as a treatment for glioma patients.

9. our results indicated that CAP1 participated in the molecular pathological process of glioma

10. a high expression of CAP1 is involved in the pathogenesis of EOC, and that the downregulation of CAP1 in tumor cells may be a therapeutic target for the treatment of patients with EOC.

11. This study demonstrated an inverse relationship between CAP1 and MMP-9 expression, high expression of MMP-9 and low expression of CAP1 in those with chronic obstructive pulmonary disease compared with the non-chronic obstructive pulmonary disease group.

12. CAP1 is involved in the brain metastasis in non-small cell lung cancer.CAP1 overexpression is associated with poor prognosis in non-small cell lung cancer patients.

13. Overexpression of CAP1 in monocytes enhanced the resistin-induced increased activity of the cAMP-dependent signaling.

14. results indicate that upregulated expression of CAP1 might contribute heavily to the metastasis of hepatocellular carcinoma.

15. Overexpression of CAP1 is associated with breast carcinoma.

16. CAP1 might be a potential molecular targeted therapy for surgery and immune treatment.

17. overexpression of CAP1 in lung cancer cells, particularly at the metastatic stage, may have significant clinical implications as a diagnostic/prognostic factor for lung cancer.

18. CAP1 depletion also led to changes in cofilin phosphorylation and localization as well as activation of focal adhesion kinase (FAK) and enhanced cell spreading.

19. Findings suggest that CAP1 (cyclase-associated protein 1) is involved in the metastasis of esophageal squamous cell carcinoma, and increased expression may indicate a poor prognosis.

20. This protein has been found differentially expressed in thalami from patients with schizophrenia.

Mouse (Murine) CAP, Adenylate Cyclase-Associated Protein 1 (Yeast) (CAP1) interaction partners

1. we purified an INF2 inhibitor from mouse brain tissue, and identified it as a complex of lysine-acetylated actin (KAc-actin) and cyclase-associated protein (CAP). Inhibition of INF2 by CAP-KAc-actin is dependent on the INF2 diaphanous inhibitory domain (DID).

2. The structural basis of actin monomer re-charging by CAP1 protein has been reported.

3. Phosphorylation regulates CAP1 function through association with cofilin and actin in order to control the actin cytoskeleton.

4. a novel inhibitory interaction between CAP1/Prss8 and nexin-1, opening the search for specific CAP1/Prss8 antagonists that are independent of its catalytic activity

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6. CAP1 depletion also led to changes in cofilin phosphorylation and localization as well as activation of focal adhesion kinase (FAK) and enhanced cell spreading.

7. study provides evidence that catalyzing nucleotide exchange on actin monomers via the beta-sheet domain is the most highly conserved function of CAPs from mammals to apicomplexan parasites.

8. CAP1 is widely expressed in mouse nonmuscle cells and promotes cofilin-induced actin dynamics.

9. CAP1 shows a broad tissue distribution and localizes to the cytoplasm

10. Postsynaptic adenylyl cyclase 1 is required for functional maturation of thalamocortical synapses and morphological barrels.

11. These studies suggest that CAP1 provides a direct link from the actin cytoskeleton to the mitochondria by functioning as an actin shuttle.

Zebrafish CAP, Adenylate Cyclase-Associated Protein 1 (Yeast) (CAP1) interaction partners

1. cap1 regulates cortical actin distribution specifically in the anterior mesendoderm of the zebrafish gastrula.

2. The requirement of Cap1 for a cellular apical constriction step suggests a conservation of gene function for a cell biological event critical to many developmental processes.

Cow (Bovine) CAP, Adenylate Cyclase-Associated Protein 1 (Yeast) (CAP1) interaction partners

1. Bovine herpesvirus 1 infection stimulates caspase 1 activity.