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Human CRP Protein expressed in HEK-293 Cells - ABIN6253726
Meyer, Ueland: Targeted quantification of C-reactive protein and cystatin c and its variants by immuno-MALDI-MS. in Analytical chemistry 2014
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Serum C-reactive protein (and COMP (show COMP Proteins)) levels were both associated with the incidence of knee osteoarthritis.
coexistence of both higher HCY and higher hs-CRP in the acute phase of ischemic stroke were associated with subsequent PSD, independently of established conventional risk factors
Data suggest that C-reactive-protein (CRP) concentration is weakly associated with global DNA methylation (show HELLS Proteins) level, and this association was more clearly in individuals with the minor allele of the 5,10-methylenetetrahydrofolate reductase (MTHFR (show MTHFR Proteins))missense SNP rs1801133.
A longitudinal association between adolescent CRP levels and adult schizophrenia diagnosis indicates a potentially important role of inflammation in the pathogenesis of the illness
rs1205 genetic variability in the CRP gene determines the CRP levels in sepsis of different severities
CRP levels predict the development of anastomotic leak and postoperative mortality after colorectal cancer surgery.
Uremia patients receiving maintenance hemodialysis with hospitalacquired infection had increased serum inflammatory factors and high throughput hemodialysis significantly decreased CRP, IL2 (show IL2 Proteins) and TNFalpha (show TNF Proteins) levels in the serum, suggesting that high throughput hemodialysis may be beneficial for the prevention of the infections in uremia patients.
High CRP expression is associated with cardiovascular disease.
The results of this meta-analysis suggest that increased CRP expression indicates a poorer prognosis in patients with bone neoplasms.
C-reactive protein (CRP) recognized 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-l-serine (POPS) and 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1 (show PHOSPHO1 Proteins)'-rac (show AKT1 Proteins)-glycerol) (POPG) in the supported 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) monolayers without calcium at pH 7.4 and 5.5.
Enhanced external counterpulsation decreased C-reactive protein and increased flow-mediated dilation in hypercholesterolemia.
serum C-reactive protein correlates with macrophage accumulation and coronary artery disease in hypercholesterolemic pigs
CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H (show NQO1 Proteins) oxidase via p38 (show MAPK14 Proteins) kinase activation.
The present study shows that elevated levels of serum CRP and IL-10 (show IL10 Proteins) were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS. (postweaning multisystemic wasting syndrome)
These data suggest that CRP might play a pathogenic role in the development of myointimal hyperplasia in polytetrafluoroethylene grafts.
myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Proteins) cyclo-oxygenase-2, monocyte chemoattractant protein-1 (show CCL2 Proteins) and CRP
CRP stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2 (show PTGIR Proteins)) synthesis.
Data show that during posttranplant obliterative bronchiolitis development, CRP is localized in inflammatory cells, myofibroblasts and endothelial cells probably as a part of the local inflammatory response.
CRP is pathogenic in type-2 diabetes (T2DN). CRP may promote CD32b- NF-kappaB (show NFKB1 Proteins) signaling to mediate renal inflammation; whereas, CRP may enhance renal fibrosis in T2DN via CD32b-Smad3 (show SMAD3 Proteins)-mTOR (show FRAP1 Proteins) signaling.
FcgammaRIIb and FcgammaRIII are involved in the CRP-induced expression of MMPs and TIMP-1 and the CRP-induced phosphorylation of p38, whereas the FcgammaR-independent pathway may regulate the CRP-induced MMP-11 expression and the CRP-induced ERK1/2 phosphorylation.
C-reactive protein may promote acute kidney injury by impairing tubular epithelial cell regeneration via the CD32-Smad3 (show SMAD3 Proteins)-p27 (show CDKN1B Proteins)-driven inhibition of the CDK2 (show CDK2 Proteins)/cyclin E (show CCNE1 Proteins) complex.
These results suggested that CRP/oxidized low density lipoprotein/beta 2-Glycoprotein I (show APOH Proteins) complexes may induce lipid accumulation and inflammation in macrophages via the p38/MAPK (show MAPK14 Proteins) and NFkappaB signaling pathways.
these data unexpectedly identify CBS (show CBS Proteins) as the major recognition site of mCRP and suggest that this motif may be exploited to tune the proinflammatory actions of mCRP.
CRP decreased adiponectin expression and multimerization, while CRP-induced decline in adiponectin might be mediated through the PI3K/Akt (show AKT1 Proteins) pathway.
Effects of C-Reactive Protein on the Cardiac Differentiation of Mouse Embryonic Stem Cells
These data indicated that CRP may have a direct role on osteoclast and osteoblast differentiation via toll (show TLR4 Proteins)-like receptor signaling pathways.
Data suggest that serum amyloid P (SAP (show APCS Proteins)) activates CD209 DC-SIGN (show CD209 Proteins) to regulate the innate immune system differently from C-reactive protein (CRP), and that DC-SIGN (show CD209 Proteins) is a target for antifibrotics.
the acute phase protein (show ORM1 Proteins) C (show PROC Proteins)-reactive protein (CRP), a ligand for Fc receptors on phagocytes, enhances antibody-mediated platelet destruction by phagocytes in vivo
data show, for the first time, a significant increase of c-reactive protein (CRP) in the blood of calves 1 d after colostrum intake.
Rabbit CRP acute-phase system binds phosphocholine and phosphoethanolamine.
IL-6 (show IL6 Proteins) augments mechanical strain-induced CRP synthesis in vessels via the stretch-activated channel-NF-kappaB (show NFKB1 Proteins) pathway.
CRP antagonism of eNOS (show NOS3 Proteins) is mediated by coupling of FcgammaRI (show FCGR1A Proteins) to FcgammaRIIB by Src kinase (show CSK Proteins) and activation of inositol 5'-phosphatase 1, and consistent with this mechanism, both FcgammaRI (show FCGR1A Proteins) and FcgammaRIIB are required for CRP to blunt endothelial repair in vivo.
Metformin attenuated the progression of aortic atherosclerosis via down-regulation of serum C-reactive protein.
crystal of C-reactive protein diffracted to 2.3 A resolution and belonged to space group R3, with unit-cell parameters a = b = 114.7, c = 61.0 A
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.
, pentraxin 1
, C-reactive protein, petaxin related
, C-reactive protein member of the pentraxin family
, C-reactive protein, member of the pentraxin family
, amyloid P component, serum
, serum amyloid P component
, pentraxin-related C-reactive protein
, uncharacterized protein LOC751795