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Human CRP Protein expressed in HEK-293 Cells - ABIN2487343
Meyer, Ueland: Targeted quantification of C-reactive protein and cystatin c and its variants by immuno-MALDI-MS. in Analytical chemistry 2014
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Study showed that high levels of C-reactive protein (CRP) were induced and correlated with complement activation in patients infected with severe influenza A (H5N1, H7N9 or H10N8), and higher levels were induced in fatal patients than in survivors. These results propose that CRP is involved in deterioration of severe influenza diseases.
This present study highlighted the predictive role of preoperative CRP concentrations for Postoperative delirium in elderly patients undergoing laparoscopic surgery for colon carcinoma.
In patients with resistant hypertension, elevated serum CRP levels predict worse cardiovascular prognosis above and beyond other cardiovascular risk factors, including ambulatory blood pressure levels and dipping patterns.
among elderly Chinese individuals, 2 common CRP gene polymorphisms (rs1205 and rs3093059) were significantly associated with CRP levels; however, none of them was associated with frailty
Schoolchildren who were overweight/obese had higher levels of CRP and IL-6 (show IL6 Proteins), whereas individuals with WC and BF% alterations had higher levels of CRP.
Plasma CRP was not altered after stress in patients with a positive stress test or those with a negative stress test.
Both a CRP level 5mg/l and SNP rs1800947 of the CRP gene were independent risk factors for further adverse CV events among patients with CVD within three years follow-up.
Increased serum IL-6 (show IL6 Proteins) and CRP are associated with clinically significant differences in upper and lower extremity muscle strength and may be useful in identifying those at risk for weakness and decreased physical function.
High-sensitivity C-reactive protein is elevated in Chinese men who drink alcohol.
Data suggest that assessment of nutritional status and of prognostic indexes are good tools for predicting postoperative complications and clinical outcome in patients with gastrointestinal neoplasia; a positive correlation was found between weight loss percentage with serum CRP levels, Prognostic Inflammatory Nutritional Index, and Glasgow score.
C-reactive protein may promote acute kidney injury by impairing tubular epithelial cell regeneration via the CD32-Smad3 (show SMAD3 Proteins)-p27 (show CDKN1B Proteins)-driven inhibition of the CDK2 (show CDK2 Proteins)/cyclin E (show CCNE1 Proteins) complex.
These results suggested that CRP/oxidized low density lipoprotein/beta 2-Glycoprotein I (show APOH Proteins) complexes may induce lipid accumulation and inflammation in macrophages via the p38/MAPK (show MAPK14 Proteins) and NFkappaB signaling pathways.
these data unexpectedly identify CBS (show CBS Proteins) as the major recognition site of mCRP and suggest that this motif may be exploited to tune the proinflammatory actions of mCRP.
CRP decreased adiponectin expression and multimerization, while CRP-induced decline in adiponectin might be mediated through the PI3K/Akt (show AKT1 Proteins) pathway.
Effects of C-Reactive Protein on the Cardiac Differentiation of Mouse Embryonic Stem Cells
These data indicated that CRP may have a direct role on osteoclast and osteoblast differentiation via toll (show TLR4 Proteins)-like receptor signaling pathways.
Data suggest that serum amyloid P (SAP (show APCS Proteins)) activates CD209 DC-SIGN (show CD209 Proteins) to regulate the innate immune system differently from C-reactive protein (CRP), and that DC-SIGN (show CD209 Proteins) is a target for antifibrotics.
the acute phase protein (show ORM1 Proteins) C (show PROC Proteins)-reactive protein (CRP), a ligand for Fc receptors on phagocytes, enhances antibody-mediated platelet destruction by phagocytes in vivo
CRP has therapeutic potential against cancer through decreasing the accumulation of M2 macrophages and angiogenesis within tumors.
Orphan nuclear receptor (show NR1D1 Proteins) Errgamma (show ESRRG Proteins) induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH (show CREB3L3 Proteins).
data show, for the first time, a significant increase of c-reactive protein (CRP) in the blood of calves 1 d after colostrum intake.
Enhanced external counterpulsation decreased C-reactive protein and increased flow-mediated dilation in hypercholesterolemia.
serum C-reactive protein correlates with macrophage accumulation and coronary artery disease in hypercholesterolemic pigs
CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H (show NQO1 Proteins) oxidase via p38 (show MAPK14 Proteins) kinase activation.
The present study shows that elevated levels of serum CRP and IL-10 (show IL10 Proteins) were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS. (postweaning multisystemic wasting syndrome)
These data suggest that CRP might play a pathogenic role in the development of myointimal hyperplasia in polytetrafluoroethylene grafts.
myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Proteins) cyclo-oxygenase-2, monocyte chemoattractant protein-1 (show CCL2 Proteins) and CRP
CRP stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2 (show PTGIR Proteins)) synthesis.
Data show that during posttranplant obliterative bronchiolitis development, CRP is localized in inflammatory cells, myofibroblasts and endothelial cells probably as a part of the local inflammatory response.
Rabbit CRP acute-phase system binds phosphocholine and phosphoethanolamine.
IL-6 (show IL6 Proteins) augments mechanical strain-induced CRP synthesis in vessels via the stretch-activated channel-NF-kappaB (show NFKB1 Proteins) pathway.
CRP antagonism of eNOS (show NOS3 Proteins) is mediated by coupling of FcgammaRI (show FCGR1A Proteins) to FcgammaRIIB by Src kinase (show CSK Proteins) and activation of inositol 5'-phosphatase 1, and consistent with this mechanism, both FcgammaRI (show FCGR1A Proteins) and FcgammaRIIB are required for CRP to blunt endothelial repair in vivo.
Metformin attenuated the progression of aortic atherosclerosis via down-regulation of serum C-reactive protein.
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.
, pentraxin 1
, C-reactive protein, petaxin related
, C-reactive protein member of the pentraxin family
, C-reactive protein, member of the pentraxin family
, amyloid P component, serum
, serum amyloid P component
, LIM only protein HLP
, cysteine-rich protein 2
, heart LIM protein
, contiguous repeat polypeptide
, glutamine/glutamic acid-rich protein B
, submandibular gland secretory Glx-rich protein CB