Browse our anti-LGALS1 (LGALS1) Antibodies

Full name:: anti-Lectin, Galactoside-Binding, Soluble, 1 Antibodies (LGALS1)

On www.antibodies-online.com are 306 Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) Antibodies from 30 different suppliers available. Additionally we are shipping LGALS1 Kits (81) and LGALS1 Proteins (55) and many more products for this protein. A total of 457 LGALS1 products are currently listed.

Synonyms:: AA410090, Gal-1, GAL1, Galaptin, Galbp, galectin-1, GB10026, GBP, L-14.5, L14, Lect14, LGALS1, LGAS1, MGC64502

list all antibodies	Gene Name	GeneID	UniProt
	LGALS1	3956	P09382
	LGALS1	56646	P11762
	LGALS1	16852	P16045
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Most Popular Reactivities for anti-LGALS1 (LGALS1) Antibodies

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anti-Human LGALS1 Antibodies:

anti-Rat (Rattus) LGALS1 Antibodies:

anti-Mouse (Murine) LGALS1 Antibodies:

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Top referenced anti-LGALS1 Antibodies

Mouse (Murine) Polyclonal LGALS1 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899423 : Silva-Monteiro, Reis Lorenzato, Kenji Nihei, Junqueira, Rabinovich, Hsu, Liu, Savino, Chammas, Villa-Verde: Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. in The American journal of pathology 2007 (PubMed)
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Human Polyclonal LGALS1 Primary Antibody for CyTOF, FACS - ABIN4899422 : Yazawa, Geddes-Sweeney, Cedeno-Laurent, Walley, Barthel, Opperman, Liang, Lin, Schatton, Laga, Mihm, Qureshi, Widlund, Murphy, Dimitroff: Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential. in The Journal of investigative dermatology 2015 (PubMed)
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Human Polyclonal LGALS1 Primary Antibody for IHC, IHC (p) - ABIN4313208 : Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006 (PubMed)
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Human Monoclonal LGALS1 Primary Antibody for IF, IP - ABIN561662 : Tan, Tan, Lin, Lim, Hew, Chung: Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells. in Molecular & cellular proteomics : MCP 2008 (PubMed)
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Human Polyclonal LGALS1 Primary Antibody for IF, WB - ABIN517485 : Doe, Wuebbles, Allred, Rooney, Elorza, Burkin: Transgenic overexpression of the ?7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A. in Journal of cell science 2011 (PubMed)
Human Polyclonal LGALS1 Primary Antibody for IF (p), IHC (p) - ABIN718586 : Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. in Biology of sex differences 2015 (PubMed)
Human Polyclonal LGALS1 Primary Antibody for IF, IHC (p) - ABIN2473743 : Resnick: Should the "worst case scenario" be universal for chloramines? in Nephrology news & issues 1990 (PubMed)
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Human Polyclonal LGALS1 Primary Antibody for ELISA, WB - ABIN2473744 : Camby, Le Mercier, Lefranc, Kiss: Galectin-1: a small protein with major functions. in Glycobiology 2006 (PubMed)
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Human Monoclonal LGALS1 Primary Antibody for ELISA, FACS - ABIN5582500 : Couraud, Casentini-Borocz, Bringman, Griffith, McGrogan, Nedwin: Molecular cloning, characterization, and expression of a human 14-kDa lectin. in The Journal of biological chemistry 1989 (PubMed)

More Antibodies against LGALS1 Interaction Partners

Human Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

Results show that Galectin-1 teams up with Galectin-3 (show LGALS3 Antibodies) to induce inflammatory/pro-degradative gene signature in human chondrocytes affecting the progression of osteoarthritis. Also, Galectin-3 (show LGALS3 Antibodies) was found to induce a pro-degradative-inflammatory gene signature in human chondrocytes, teaming up with Galectin-1 in the pathogenesis of osteoarthritis.
We also found a subset of prostate cancer patient-derived xenografts and prostate cancer patient samples with mild HO-1 (show HMOX1 Antibodies) and low Gal-1 expression levels. These results highlight a novel function of a human-used drug as a means of boosting the antitumor response
Gal-1, Gal-3 (show LGALS3 Antibodies) and Gal-9 (show LGALS9 Antibodies) galectin expression was higher in the myenteric plexus ganglia of chagasic patients
Results have shown that Gal-1 in the farnesyl-bound form acquires the ability to form self-clusters, and the galactoside-binding pocket of Gal-1 in the FTS (show AKTIP Antibodies)-bound form plays an important role in self-cluster formation.
Our findings support the introduction of galectin-1 as a reliable diagnostic marker for thyroid carcinomas. Its involvement in cell proliferation, migration, invasion and tumor growth also intimate functional involvement of galectin-1 in the progression of thyroid carcinoma, suggesting its potential as a therapeutic target
This study showed that obese children had significantly higher galectin-1 levels in proportion to fat mass in obese cases than those in healthy children, which may be interpreted as a compensatory increase in an attempt to improve glucose metabolism.
We further demonstrated using the NMR-based hydrogen-deuterium exchange (HDX) that lactose binding increases the exchange rates of residues located on the opposite side of the ligand-binding pocket for hGal1 and hGal8(NTD), indicative of allostery. Additionally, lactose binding induces significant stabilisation of hGal8(CTD) across the entire domain
our findings indicate that galectin-1 plays a pivotal role in the regulation of key processes in cancer cells, such as migration, invasion, and chemoresistance, by modulating FAK (show PTK2 Antibodies) and ERK (show EPHB2 Antibodies) signaling and survivin (show BIRC5 Antibodies) level.
Gal-3 (show LGALS3 Antibodies) staining in the nucleus could be a new positive prognosticator for ovarian cancer.
Gal-1 may offer an additional therapeutic target linking anti-angiogenesis and immune checkpoint blockade.

Pig (Porcine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

Gal-1 may serve as an adhesion molecule (show NCAM1 Antibodies) to interact with both cells and laminins
Gal-1 is expressed in a wide range of porcine tissues, including striated (show NSDHL Antibodies) muscle, liver, lung, brain, kidney, spleen, and intestine
LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

Data suggest that galectin-1 and VEGFR-2 (show KDR Antibodies) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (show KDR Antibodies) in luteal cells.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1, LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 (show LGALS9 Antibodies) mRNA would display a differential expression pattern in the endometrium.
The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

This work identified Gal1, an endogenous immune regulatory lectin, as an integral component of the secretory granule machinery and unveil the unexpected function of this lectin in regulating CTL killing activity.
The results of this study showed that development of spinal axons as well as the locomotor abilities observed in adult mice are independent of Gal-1.
GAL-1 also enhanced the generation of neural crest cells from explanted neural tubes
this present study indicated that Gal-1 secreted from MSCs upregulated expression of Gal-1 and stimulated formation of tolerance immunophenotype on DCs, where the underlying mechanism was the regulation of the MAPK (show MAPK1 Antibodies) signaling pathway in DCs, thereby inhibiting the function of DCs
markedly increased brain Gal-1 and S-nitrosylated Gal-1 both in scrapie-infected rodents and human prion (show PRNP Antibodies) diseases.
Gal-1 can limit eosinophil recruitment to allergic airways and suppresses airway inflammation by inhibiting cell migration and promoting eosinophil apoptosis.
Gal1 protein is essential for efficient liver regeneration following partial hepatectomy through the regulation of liver inflammation, hepatic cell proliferation, and the control of lipid storage in the regenerating liver.
findings show that galectin-1 (Gal-1), an immunoregulatory lectin widely expressed in mucosal tissues, contributes to Y. enterocolitica pathogenicity by undermining protective antibacterial responses.
Gal-1 functions as an important regulator in RNV and offers a promising strategy for the treatment of RNV diseases, such as proliferative diabetic retinopathy and retinopathy of prematurity.
These findings demonstrate that galectin-1 is required for i.v. tolerance induction, likely via induction of tolerogenic DCs leading to enhanced development of Tr1 (show TXNRD1 Antibodies) cells, Treg cells, and downregulation of proinflammatory responses.

Horse (Equine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

Equine bone marrow mesenchymal stromal cells constitutively express high levels of galectin-1 mRNA relative to other articular cell types, suggesting a possible mechanism for their intra-articular immunomodulatory properties.

LGALS1 Antigen Profile

Antigen Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

Alternative names and synonyms associated with LGALS1

galectin 1 (LGALS1) antibody
galectin 1 (Lgals1) antibody
galectin-1 (CC1G_05003) antibody
galectin-1 (CC1G_05004) antibody
lectin, galactoside-binding, soluble, 1 L homeolog (lgals1.L) antibody
protein enabled (LOC408848) antibody
lectin, galactose binding, soluble 1 (Lgals1) antibody

AA410090 antibody
Gal-1 antibody
GAL1 antibody
Galaptin antibody
Galbp antibody
galectin-1 antibody
GB10026 antibody
GBP antibody
L-14.5 antibody
L14 antibody
Lect14 antibody
LGALS1 antibody
LGAS1 antibody
MGC64502 antibody

Protein level used designations for LGALS1

, , , , , , , , , , , , , , , , , , , , , , , , , , , 14 kDa laminin-binding protein 14 kDa lectin HBL HLBP14 HPL S-Lac lectin 1 beta-galactoside-binding lectin L-14-I beta-galactoside-binding protein 14kDa gal-1 galaptin galectin 1 galectin-1 lactose-binding lectin 1 putative MAPK-activating protein PM12 lectin galactoside-binding soluble 1 beta-galactoside-binding lectin RL 14.5 lectin, galactose binding, soluble 1 lectin, galactoside-binding, soluble, 1 (galectin 1) 14K beta-galactoside-binding lectin C-14 galectin CG-1B gbl lectin, galactoside-binding, soluble, 1 beta-galactoside binding protein Beta-galactoside-binding lectin L-14-I Lactose-binding lectin 1 Lectin galactoside-binding soluble 1

GENE ID	SPECIES
3956	Homo sapiens
100173289	Pongo abelii
414915	Sus scrofa
100196938	Papio anubis
56646	Rattus norvegicus
326598	Bos taurus
443298	Ovis aries
396491	Gallus gallus
6012550	Coprinopsis cinerea okayama7130
6012551	Coprinopsis cinerea okayama7#130
379433	Xenopus laevis
742148	Pan troglodytes
408848	Apis mellifera
16852	Mus musculus
100722354	Cavia porcellus
610276	Canis lupus familiaris
100069841	Equus caballus
100751963	Cricetulus griseus
700896	Macaca mulatta

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Show all anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) Antibodies with Pubmed References