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High VCAM1 expression is associated with Cardiovascular Disease.
We observed an increase of VCAM-1 urine levels in diabetic nephropathy-basal patients compared to diabetic controls and an increase of urinary neprilysin (show MME Proteins) in DN-treated patients with persistent albuminuria
Urinary angiostatin and VCAM-1 are predictive of specific histological changes in concurrent lupus nephritis renal biopsies.
In summary, it could be concluded that the expression of gene VCAM-1 was down regulated by taurocholic acid through miR (show MLXIP Proteins)-590-3p and that gene VCAM-1 could participate in the regulation of cell growth, cell proliferation and cell apoptosis
VCAM-1 expression is upregulated by CD34+/CD133+-stem cells derived from septic patients
Circulating soluble vascular cell adhesion molecule (show MCAM Proteins) (VCAM-1) level was a useful diagnostic parameter for understanding the difference between coronary artery disease (CAD) and cardiac syndrome X (CSX (show NKX2-5 Proteins)).
findings indicate a novel role for JAK2 (show JAK2 Proteins)-V617F in activation of beta1 integrins and enhanced adhesion of granulocytes and 32D myeloid progenitors to VCAM1-coated surfaces
High VCAM1 expression is associated with Cardiovascular Disease Risk.
VCAM-1 levels are elevated in serum of cystic fibrosis (show S100A8 Proteins) patients.
VCAM-1 levels are able to accurately predict significant fibrosis in non-alcoholic fatty liver disease patients
These studies showed that VCAM1 contributes not only to the initiation of myelination but also to its regulation through controlling the abundance of CD69 (show CD69 Proteins), demonstrating that an intercellular molecule whose primary role is in the immune system can also play an unexpected role in the CNS.
Results showed that MOVACs transfected with pCMV5-HA-RKIP (show PEBP1 Proteins) significantly inhibited TNF-a (show TNF Proteins) induced mRNA and protein expression of ICAM-1 (show ICAM1 Proteins) and VCAM-1.
VCAM-1 promotes CD34 (show CD34 Proteins)(+)VLA-4(+) cell mobilization into the damaged myocardial tissues.
These studies define differential roles for VCAM-1 in SC depending on the state of their niche.
VCAM1 affects the neural stem cells fate by signaling through its intracellular domain to regulate beta-catenin (show CTNNB1 Proteins) signaling in a context-dependent manner
Reducing Cadm1 (show CADM1 Proteins) expression in the hypothalamus and hippocampus promoted a negative energy balance and weight loss
Here we delineated an inflammation-driven inhibitory mechanism of beige adipogenesis in obesity that required direct adhesive interactions between macrophages and adipocytes mediated by the integrin alpha4 and its counter-receptor VCAM-1, respectively; expression of the latter was upregulated in obesity.
High VCAM1 expression is associated with Experimental Autoimmune Myocarditis
Aortic VCAM-1 was expressed early and indicated vascular inflammation in collagen-induced arthritis.
this manuscript shows that endothelial cell FAK (show PTK2 Proteins) activity induces VCAM-1 expression and contributes to atherosclerosis
Protein kinase A-alpha directly phosphorylates FoxO1 (show FOXO1 Proteins) in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (show NCAM1 Proteins)-1 mRNA.
the p38-MAPK (show MAPK14 Proteins)/CREB (show CREB1 Proteins) pathway plays a critical role in TNFalpha (show TNF Proteins)-induced VCAM-1 expression
Data show that all five molecules, BNP, ICAM-1 (show ICAM1 Proteins), TNF-alpha (show TNF Proteins), VCAM-1 and IL-6 (show IL6 Proteins), quickly and reliably signaled adverse interactions.
Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 (show ICAM1 Proteins) in a BMP-4 (show BMP4 Proteins)- and TGF-beta1 (show TGFB1 Proteins)-dependent pathway.
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
, vascular cell adhesion protein 1
, V-CAM 1
, vascular cell adhesion molecule-1
, vascular cell adhesion molecule 1
, vascular cell adhesion protein 1-like