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anti-Human ARL2 Antibodies:
anti-Mouse (Murine) ARL2 Antibodies:
anti-Rat (Rattus) ARL2 Antibodies:
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Human Polyclonal ARL2 Primary Antibody for ELISA, WB - ABIN249610
Clark, Moore, Krasinskas, Way, Battey, Tamkun, Kahn: Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes. in Proceedings of the National Academy of Sciences of the United States of America 1993
Human Polyclonal ARL2 Primary Antibody for IHC, IHC (p) - ABIN4281598
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
conclude that the TBCD (show TBCD Antibodies)*ARL2*beta-tubulin (show TUBB Antibodies) complex represents a functional intermediate in the beta-tubulin (show TUBB Antibodies) folding pathway whose activity is regulated by the cycling of nucleotides on ARL2
Results identified ARL2 and TBCD (show TBCD Antibodies), as important in tubulin (show TUBB Antibodies) folding and microtubule dynamics. Both ARL2 and TBCD (show TBCD Antibodies) also localize to centrosomes. A growing body of evidence also has found roles for ARL2 inside mitochondria, as a regulator of mitochondrial fusion, and in the traffic of farnesylated cargos between membranes and specifically to cilia and photoreceptor cells. [review]
In conclusion, our study revealed that miR (show MLXIP Antibodies)-214 acts as a tumor suppressor via inhibiting proliferation, migration and invasion of cervical cancer cells through targeting ARL2, and that both miR (show MLXIP Antibodies)-214 and ARL2 may serve as prognostic or therapeutic targets for cervical cancer.
Novel Biochemical and Structural Insights into the Interaction of Myristoylated Cargo with Unc119 (show UNC119 Antibodies) Protein and Their Release by Arl2/3.
We hypothesize that ARL2 plays essential roles inside mitochondria along with other cellular functions, at least in part to provide coupling of regulation between these essential cell processes.
MiR (show MLXIP Antibodies)-195 regulates cell apoptosis in a context-dependent manner through directly targeting ARL2.
The G proteins Arl2 acts in a GTP (show AK3 Antibodies)-dependent manner as allosteric release factors for farnesylated cargo.
a novel function of miR-16 (show GDE1 Antibodies) targeting ARL2 in modulating proliferation and cell cycle progression.
Data show that bovine and human TBCD (show TBCD Antibodies) have functionally identical roles in tubulin (show TUBB Antibodies) heterodimer assembly, and that the inability of human TBCD (show TBCD Antibodies) to disrupt microtubule integrity can be overcome by siRNA-mediated suppression of expression of Arl2.
C. elegans evl-20 gene encodes a functional homolog of human ARL2. Elimination of evl-20 function results in abnormal vulval, gonad, and male tail development and disrupts embryonic proliferation, hypodermal enclosure, and elongation.
two pathways in mitochondria, one affecting ATP levels that is independent of ELMOD2 (show ELMOD2 Antibodies) and the other leading to mitochondrial fusion involving MFN2 (show MFN2 Antibodies) that does involve ELMOD2 (show ELMOD2 Antibodies)
Studies indicate that Arf-like proteins ARL2 and ARL3 are not substrates for N-myristoyl transferase.
Arl2, a small GTPase (show RACGAP1 Antibodies), has an important regulator of breast tumor cell aggressivity, both in vitro and in vivo
Arf-like protein 2 interaction with PDEdelta is dependent on GTP (show AK3 Antibodies), and the binding of PDEdelta substantially stabilizes GTP binding (show RND2 Antibodies); data suggests that Arl2/3 are specific regulators of PDEdelta
This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes.
ADP-ribosylation factor-like 2
, ADP-ribosylation factor-like protein 2
, ADP-ribosylation-like 2
, arf-like protein 2