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anti-Human CD7 Antibodies:
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Human Monoclonal CD7 Primary Antibody for FACS - ABIN536113
Lam, Liao, Xue, Alam, Scearce, Kaufman, Sempowski, Haynes: Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma. in Journal of clinical immunology 2005
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Human Monoclonal CD7 Primary Antibody for FACS - ABIN4369573
Chang, Yeung, Brandwein, Yi: CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype. in Leukemia research 2006
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Human Monoclonal CD7 Primary Antibody for FACS - ABIN536116
Nishimura, Takanashi, Okazaki, Satake, Nakajima: Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M. in Endothelium : journal of endothelial cell research 2006
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Human Monoclonal CD7 Primary Antibody for FACS - ABIN1383807
Wang, Kvalheim, Kvaløy, Beiske, Jakobsen, Wijdenes, Pihl, Fodstad: An effective immunomagnetic method for bone marrow purging in T cell malignancies. in Bone marrow transplantation 1992
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Human Monoclonal CD7 Primary Antibody for FACS, IHC (p) - ABIN94218
Rappl, Riet, Awerkiew, Schmidt, Hombach, Pfister, Abken: The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells. in PLoS ONE 2012
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Human Monoclonal CD7 Primary Antibody for IHC (fro), FACS - ABIN2689381
Rabinowich, Pricop, Herberman, Whiteside: Expression and function of CD7 molecule on human natural killer cells. in Journal of immunology (Baltimore, Md. : 1950) 1994
in acute myeloid leukemia patients the association of CD7 positivity and FLT3 positivity was found to be significant
Data show that CD7 promotes extramedullary involvement of the B-ALL line Tanoue in an integrin beta2-dependent manner.
We showed that the CADM1 versus CD7 plot is capable of discriminating clonally expanding HTLV-I-infected cells in indolent and acute-type T-cell leukemia-lymphomas and in asymptomatic carriers
CD7 is present on monocytes and tumor macrophages and its ligand, SECTM1, is frequently expressed in corresponding melanoma tissues
SECTM1 secreted from bone marrow stromal cells may interact with CD7 to influence GM-CSF expression in leukemic cells.
epigenetic down-regulation of CD7 is associated with acute myeloid leukemia.
CD7 loss in aggressive natural killer-cell leukemia; a useful diagnostic marker
low expression in T-cell lymphomas due to Twist2-mediated suppression of promoter activity; enhanced by histone deacetylase inhibitors
These findings indicate a link between epigenetic modifications and CD7 expression in primitive chronic myeloid leukemia cells.
CD7 expression in hematopoitic cells denotes commitment to B-cell and natural killer cells lineages.
Association of T cell antigen CD7 with type II phosphatidylinositol-4 kinase, a key component in pathways of inositol phosphate turnover.
a novel fusion protein, designated scFvCD7:sFasL is designed to have leukemia-restricted activity.
Patients expressing CD7 had significant shorter disease free (DFS) and post-remission survivals (PRS) than patients without CD7 (DFS of 12 months versus 42 months, P=0.005; PRS of 15 months versus 33 months, P=0.013).
CD7 antigen notably expresses in lung microvascular endothelial cells (LME) and that it acts as an Fc receptor for IgM in LME cells.
HTLV-IInfected cells acquired a profound decrease of intracellular calcium levels in response to ionomycin, timely correlated with decreased CD7 expression
differential levels of CD7 identify the progressive stages of lineage commitment in human thymus, initiated from a primitive CD7(-) lympho-myeloid thymic progenitor
close association of aberrant CD7 expression and FLT3/ITD mutation in the myeloblasts of FLT3/ITD+ acute myeloid leukemia suggests that FLT3/ITD- mediated leukemic transformation occurs in the more early stage of myeloid progenitor cells
The CD7 expression in CD4(+) T cells discriminates between HL and reactive LAD, suggesting that this could be a useful and practical adjunctive tool in the diagnosis of Hodgkin lymphoma.
by down-regulating CD7, ATLL cells could have escaped Gal-3-induced apoptosis to run a more aggressive clinical course
the galectin-1 glycoprotein receptor CD7 maybe a novel target for GdA on T cells.
CD7 chimeric antigen receptor T cells have robust activity against T-cell malignancies in vitro and in vivo.
Data indicate the tissue ligand SECTM1A (Secreted and transmembrane1A) as an alternative CD7 ligand.
Data demonstrate collaborative roles for both CD7 and CD28 in determination of number and function of CD4+CD25+ T regulatory cells in the thymus and peripheral immune sites and in the development of spontaneous thyroiditis.
The regulation of CD7 gene expression through NF-kappaB activation induced by TCR/CD28 might have significant implications for T-cell homeostasis.
Molecular mimicry of murine CD7 with HSP-60 is demonstrated; CD7 may regulate HSP-60 expression in mouse small intestine.
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.
CD7 antigen (p41)
, T-cell antigen CD7
, T-cell leukemia antigen
, T-cell surface antigen Leu-9
, p41 protein
, CD7 antigen