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anti-Mouse (Murine) COPS4 Antibodies:
anti-Human COPS4 Antibodies:
anti-Rat (Rattus) COPS4 Antibodies:
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Cow (Bovine) Polyclonal COPS4 Primary Antibody for WB - ABIN2774165
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
COP9 (show COPS8 Antibodies) signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster.
we link the CSN to the degradation of Cyclin E, which promotes the G1-S transition in the cell cycle and then is rapidly degraded by the ubiquitin-proteasome pathway
the CSN4 subunit of the COP9 (show COPS8 Antibodies) signalosome co-occupies retinoblastoma target gene promoters with Rbf2
CSN4 silencing decreases CSN5 (show COPS5 Antibodies) protein levels and suggest that the CSN4 effects on sGCA1 and p53 (show TP53 Antibodies) proteins are mediated by CSN5 (show COPS5 Antibodies).
Identified is a novel-binding partner of torsin A (show TOR1A Antibodies), the subunit 4 (CSN4) of CSN signalosome.
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
, COP9 signalosome subunit 4
, drosophila COP9 signalosome homolog 4
, COP9 signalosome complex subunit 4
, JAB1-containing signalosome subunit 4
, COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
, COP9 (constitutive photomorphogenic), subunit 4
, COP9 complex S4
, signalosome subunit 4
, COP9 constitutive photomorphogenic-like protein subunit 4
, COP9 constitutive photomorphogenic homolog subunit 4
, COP9 (constitutive photomorphogenic) homolog, subunit 4