Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Genotype of INCENP affect promoter activity and bovine semen quality.
INCENP labels the spermatogonia synaptonemal complex central element from zygotene up to late pachytene when it begins to relocalize to heterochromatic chromocentres
INCENP recruits Aurora-C (show AURKC Proteins) (or some other factor(s) recruit INCENP and Aurora-C (show AURKC Proteins)) to meiotic chromosomes, while Aurora-C (show AURKC Proteins) may either work alone or cooperate with Aurora-B (show AURKC Proteins) to regulate chromosome segregation during male meiosis
Aurora-C (show AURKC Proteins) interactions with members of the Chromosome Passenger Complex (CPC), Survivin (show BIRC5 Proteins) and Inner Centromere Protein (INCENP) in reference to known Aurora-B (show AURKB Proteins) interactions to understand the functional significance of Aurora-C (show AURKC Proteins) overexpression in human cancer cells, is reported.
Data unveils a novel mechanism of PRMT1 (show PRMT1 Proteins)-mediated CPC regulation through methylation of INCENP.
The data suggest that INCENP in the chromosomal passenger complex pathway contributes to estrogen receptor (show ESR1 Proteins)-negative breast cancer susceptibility in the European population.
Our results provide the structural basis and energetics of the human Aurora-A (show AURKA Proteins)(G198N) - INCENP complex
v-Src (show SRC Proteins) induces the failure of cytokinesis and the delocalization of Mklp1, Aurora B (show AURKB Proteins), and INCENP from the spindle midzone.
HP1alpha (show CBX5 Proteins) binding by INCENP or Shugoshin 1 (Sgo1 (show SGOL1 Proteins)) is dispensable for centromeric cohesion protection during mitosis of human cells, but might regulate yet unknown interphase functions of the chromosome passenger complex (CPC) or Sgo1 (show SGOL1 Proteins) at the centromeres.
Results indicate that INCENP-Aurora B (show AURKB Proteins) localized at centromeres/inner kinetochores is sufficient to mediate SAC (show ADCY10 Proteins) activity upon spindle disruption.
Dephosphorylation of INCENP at anaphase and the concomitant relocation of the chromosomal passenger protein complex prevents kinetochore recruitment of mitotic checkpoint (show BUB3 Proteins) proteins.
Data show that binding to INCENP is alone critical to the distinct function of Aurora B (show AURKB Proteins), and although G198 of Aurora A (show AURKA Proteins) is required for TPX2 (show TPX2 Proteins) binding, N142G Aurora B (show AURKB Proteins) retains INCENP binding and Aurora B (show AURKB Proteins) function.
Aurora B kinase (show AURKB Proteins) activity is stimulated by INCENP and C-terminal region of INCENP is sufficient for activation
In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A\; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994
inner centromere protein antigens 135/155kDa
, inner centromere protein B
, inner centromere protein
, similar to XL-INCENP
, inner centromere protein-like
, class I INCENP protein
, class II INCENP protein
, binds and activates aurora-B and -C in vivo and in vitro
, chromosomal passenger protein
, inner centromere protein INCENP