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Topoisomerase II alpha Proteins

(Topoisomerase (DNA) II alpha 170kDa (TOP2A))
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010].
Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) (ABIN1323347)

TOP2A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Topoisomerase II alpha Protein (AA 1-1531) (His tag) Topoisomerase II alpha Protein (AA 1-1531) (His tag) Topoisomerase II alpha Protein (AA 1-1531) (His tag) (ABIN3095949)

Crystallography grade TOP2A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS

Topoisomerase II alpha Protein (AA 1-1528) (His tag) Topoisomerase II alpha Protein (AA 1-1528) (His tag) Topoisomerase II alpha Protein (AA 1-1528) (His tag) (ABIN3134769)

Crystallography grade TOP2A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS

Topoisomerase II alpha Proteins by Grade

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Topoisomerase II alpha Proteins by Origin

Find Topoisomerase II alpha Proteins for a variety of species such as anti-Human Topoisomerase II alpha, anti-Mouse Topoisomerase II alpha, anti-Rat Topoisomerase II alpha. The species listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha Proteins by Source

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Topoisomerase II alpha Proteins by Protein Type

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Topoisomerase II alpha Proteins by Application

Find Topoisomerase II alpha Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Topoisomerase II alpha Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323347
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095949
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134769
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7013599
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751809
Quantity 5 applications
Datasheet Datasheet

Aliases for Topoisomerase II alpha Proteins

DNA topoisomerase II alpha (TOP2A) Proteins
DNA topoisomerase II, alpha isozyme (Bm1_08705) Proteins
topoisomerase (DNA) II alpha (Top2a) Proteins
DNA topoisomerase II alpha (Top2a) Proteins
topoisomerase (DNA) II alpha (TOP2A) Proteins
Zincin-like metalloproteases family protein (AT5G10540) Proteins
DNA topoisomerase II alpha (top2a) Proteins
F12B17.110 Proteins
F12B17_110 Proteins
fc08c07 Proteins
thimet metalloendopeptidase 2 Proteins
Top-2 Proteins
TOP-2 Proteins
TOP2 Proteins
TOP2A Proteins
TP2A Proteins
wu:fc08c07 Proteins
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