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anti-Human ABCA1 Antibodies:
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Chicken Polyclonal ABCA1 Primary Antibody for ChIP, ELISA - ABIN152883
Krimbou, Denis, Haidar, Carrier, Marcil, Genest: Molecular interactions between apoE and ABCA1: impact on apoE lipidation. in Journal of lipid research 2004
Show all 273 Pubmed References
Chicken Polyclonal ABCA1 Primary Antibody for ELISA, IHC (fro) - ABIN268848
Burgess, Kiss, Zheng, Zachariah, Marcel: Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux. in The Journal of biological chemistry 2002
Show all 13 Pubmed References
Chicken Polyclonal ABCA1 Primary Antibody for ELISA, ICC - ABIN268847
Murthy, Born, Mathur, Field: LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells. in Journal of lipid research 2002
Show all 13 Pubmed References
Mouse (Murine) Monoclonal ABCA1 Primary Antibody for IHC (p), WB - ABIN268899
Zhou, Choi, Li, Xu, Herz: LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. in PLoS ONE 2009
Show all 7 Pubmed References
Human Monoclonal ABCA1 Primary Antibody for CyTOF, FACS - ABIN4277133
Wang, Zhang, Chou, Liang, Gu, Ma: Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. in American journal of physiology. Renal physiology 2009
Show all 5 Pubmed References
Mouse (Murine) Monoclonal ABCA1 Primary Antibody for FACS, IF - ABIN2477218
Zarubica, Trompier, Chimini: ABCA1, from pathology to membrane function. in Pflügers Archiv : European journal of physiology 2007
that ABCA1 was a direct target of miR (show MLXIP Antibodies)-361-5p and was down-regulated in hypoxia-induced migration and apoptosis of pulmonary artery smooth muscle cells
data suggest that there are significant interactive effects between ABCA1 I883M and ALT levels on HDL (show HSD11B1 Antibodies)-C and LDL-C levels.
vaspin (show SERPINA12 Antibodies) decreased miR (show MLXIP Antibodies)-33a levels, which in turn increased ABCA1 expression and cholesteorl efflux.
ABCA1 rs2230806 had a significant association with prevalence of Type 2 Diabetes.
Confirmed by mRNA and protein expression, the amino acid transporters SLC7A7 (show Slc7a7 Antibodies) and SLC38A5 (show Slc38a5 Antibodies) showed marked differences between controls and intrauterine growth restriction/pre-eclampsia and were regulated by both diseases. In contrast, ABCA1 may play an exclusive role in the development of pre-eclempsia.
Single Nucleotide Polymorphism in ABCA1 gene is associated with dyslipidemia.
Increased expression of hepatic ABCA1 transporter is associated with hypercholesterolemia in a cholestatic rat model and primary biliary cholangitis patients.
Review/Meta-analysis: significant association of ABCA1 rs2230806 GG with increased risk of ischemic stroke.
Results showed that ABCA1 participates in the alpha-synuclein transport of cholesterol through the plasma membrane of neuronal cells.
HECTD1 (show HECTD1 Antibodies) may be involved in the regulation of ABCA1-mediated cholesterol export from unloaded macrophages to apoA-I (show APOA1 Antibodies).
our results highlight the importance of the LXR (show NR1H3 Antibodies)/ABCA1 system in brain pericytes and suggest a new role for these cells in brain cholesterol homeostasis.
The expression and distribution of the bovine ABCA1 transporter using quantitative PCR and the sequencing of the entire ABCA1 coding region, including the proximal promoter region, are reported.
Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 Antibodies) or ABCG1 (show ABCG1 Antibodies) but not ABCA1.
ABCA1 promoter variants affect transcription activity and plasma HDL (show HSD11B1 Antibodies) level in pigs
ABCA1 was up-regulated in monocytes of hypercholesterolemic pigs via oxidized-LDL and prior to development coronary atherosclerosis.
Both region-specific and ubiquitous (ABCA1) phenotype changes were identified as early prelesional responses of the endothelium to hypercholesterolemia
CSL112 elevation of ABCA1-dependent efflux may target atherosclerotic plaque for cholesterol removal.
It was concluded that quercetin inhibits oxLDLinduced lipid droplets in RAW264.7 cells by upregulation of ABCAl, ABCG1, LXRalpha and downregulation of PCSK9, p53, p21 and p16.
these results suggest that apigenin may attenuate atherogenesis through up-regulating ABCA1-mediated cholesterol efflux and inhibiting inflammation.
TMP upregulated the protein stability of ABCA1 without affecting ABCG1 (show ABCG1 Antibodies). Accordingly, TMP regulated the expression of SR-A (show MSR1 Antibodies), CD36 (show CD36 Antibodies), ABCA1 and ABCG1 (show ABCG1 Antibodies) in aortas of ApoE (show APOE Antibodies)-/- mice, which resembled the findings observed in macrophages.
HDL3, by interacting with ABCA1, modulates the miR143/145-myocardin (show MYOCD Antibodies) axis and prevents the cholesterol-induced gene expression modification in smooth muscle cells regardless of its cholesterol unloading capacity.
(1) ABCA1 maintains optimal hepatocyte PM FC, through intracellular FC trafficking, for efficient insulin (show INS Antibodies) signaling; and (2) hepatocyte ABCA1 deletion produces a form of selective insulin (show INS Antibodies) resistance so that lipogenesis is suppressed but glucose metabolism remains normal
demonstrates behavior deficits caused by Abca1 deletion in APP (show APP Antibodies)/PS1DeltaE9 mouse model at an early stage of amyloid pathology. The basal deficits of Abca1ko, manifested by diminished cognitive performance, prevent them from coping with additional stressors, which is in part due to the impairment of neurite morphology in the hippocampus.
Rutaecarpine was identified to be a candidate that protected ApoE (show APOE Antibodies)(-/-) mice from developing atherosclerosis through preferentially promoting activities of ABCA1 and SR-BI (show SCARB1 Antibodies) within RCT (show FOXE3 Antibodies).
Abca1 has a protective role in atherosclerosis, it exerts detrimental effects on cardiac function after myocardial infarction
Caveolin-1 (show CAV1 Antibodies) enhances internalization and degradation of ABCA1 by its association with ABCA1
ABCA1-derived nascent high-density lipoprotein-apolipoprotein AI (show APOA1 Antibodies) and lipids metabolically segregate.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
ATP-binding cassette sub-family A member 1
, ATP-binding cassette transporter A1
, cholesterol efflux regulatory protein
, ATP-binding cassette, sub-family A (ABC1), member 1
, ATP-binding cassette, sub-family A member 1
, ATP-binding cassette transporter 1
, Cholesterol efflux regulatory protein
, ATP-binding cassette transporter
, ATP-binding cassette, sub-family A member 1-like
, ATP-binding cassette sub-family A member 1-like
, ATP-binding cassette 1
, ATP-binding cassette, sub-family A (ABC1), member 1B