Browse our anti-Interleukin 17F (IL17F) Antibodies

Human Interleukin 17F (IL17F) interaction partners

1. Study demonstrated that rs2275913 AA functional polymorphism of IL-17F as well as IL-17 serum levels are significantly related to the risk of knee osteoarthritis susceptibility in Han Chinese population.

2. High IL-17F expression is associated with geriatric asthma.

3. an association of IL17F T7488C (rs763780) with the risk for hip osteoarthritis development in the Croatian population. Furthermore, there is a possible correlation between TLR10 (rs11096957) SNP and increased risk for hip osteoarthritis, too.

4. The present findings suggest that IL-17A (rs10484879) G/T and IL-17F (rs763780) C/T gene polymorphisms may contribute in pathogenesis of psoriasis.

5. interleukin-17F rs763780 (7488A/G) polymorphism is strongly correlated with susceptibility and severity of ITP.

6. Genetic study revealed no association between IL-17F SNPs and acute kidney transplant graft rejection. Nevertheless, a significant improvement of graft survival was found in kidney transplant recipients carrying the IL-17F-rs763780*A/A genotype.

7. expression of IL-17A, E, and F and their receptors in non-small-cell lung cancer; data suggest that IL-17A, E, F and their receptors IL-17RA, RB, RC may be involved in the pathogenesis of non-small cell lung cancer

8. CCL20 may play an important role in the pathogenesis of MS. Both allelic variation of (rs6749704) within CCL20 gene and (rs763780) within IL-17F gene can be considered risk factor for development of MS in Egyptian patients.

9. the results suggest that IL17F genetic polymorphism is not associated with the development of rheumatic heart disease in South Indian population

10. The expression of IL-6 gene and protein was significantly induced by IL-17F. IL-17F activated TAK1 and NF-kappaB in airway smooth muscle cells.

11. IL-17FA7488G polymorphism was not significantly associated with colorectal cancer risk

12. a dietary pattern reflecting inflammation was significantly associated with colorectal cancer risk and this association could be modified according to the IL-17F rs763780 genotype and anatomic site.

13. Malignant T cells activate endothelial cells via IL-17 F.

14. The AA genotype on 7489A/G single nucleotide polymorphism of IL-17F and the A allele might be associated with a lower risk of acute rejection with better graft survival in kidney transplant recipients.

15. Findings suggest that IL-17F rs1889570 gene polymorphisms are significantly associated with the susceptibility to severe EV71 infection in Chinese Han children.

16. P-TEFb is involved in IL-17F-induced IL-8 expression and that steroids diminish it via the inhibition of CDK9 phosphorylation.

17. The IL-17F (+7488A/G) genotype revealed a significantly increased risk of accelerated silicosis. The IL-17F (+7488 G) allele was associated with an increased risk of accelerated silicosis.

18. developed ultrasensitive methods for measuring IL-17A and IL-17F in human serum samples and found that serum from psoriasis patients had higher and a broader range of concentrations of both IL-17 proteins compared to healthy volunteers

19. SNPs of rs3819024 in IL-17A and rs763780 in IL-17F were weakly related to a prognosis of tuberculosis.

20. IL17F (rs2397084) and IL10 (rs1800871) genes are associated with functional dyspepsia.

Mouse (Murine) Interleukin 17F (IL17F) interaction partners

1. Secretion of interleukin (IL)-17A, IL-17F, IL-1beta, and interferon-gamma was increased upon exposure lymphoid cells to Giardia lamblia.

2. IL-17F promotes osteoblast differentiation independent of the canonical Wnt pathway and beta-catenin signaling.

3. Il17f-/- mice resisted chemically induced colitis, but Il17a-/- mice did not, and that Il17f-/- CD45RBhiCD4+ T cells induced milder colitis in lymphocyte-deficient Rag2-/- mice, accompanied by an increase in intestinal regulatory T cells

4. IL-17A and IL-17F exert distinct biological effects during pulmonary infection; the IL-17F/IL-17RC signaling axis has the potential to significantly worsen pathogen-associated inflammation of the lower respiratory tract.

5. our results indicate that Th17 cells contribute to the airway vascular remodeling in asthma by mediating EPC chemotaxis, as well as PMVEC tube formation, via IL-17A rather than IL-17F.

6. Data indicate that IL-17A repressed IL-17F secretion in vitro and in vivo.

7. The concentrations in plasma of IL-17A, IL-17F, and the IL-17AF heterodimer all were increased greatly in mice after endotoxemia.

8. IL-17A and IL-17F secreted by CD4+Th17 cells specific to lung self-antigens are critical mediators of autoimmunity leading to the pathogenesis of obliterative airway disease.

9. The Th17 subset of T-lymphocytes produces IL-17F to stimulate bone healing.

10. IL-17F is not required for development of T helper cell (Th)2-type allergic airway inflammation.

11. Together, our findings demonstrate a protective role for IL-17F in colon cancer development, possibly via inhibiting tumor angiogenesis

12. These results demonstrate that IL-17A/F plays a critical role in Legionella pneumophila pneumonia, probably through induction of proinflammatory cytokines and accumulation of neutrophils at the infection site.

13. CNS2 is sufficient and necessary for Il17 and optimal Il17f gene transcription in Th17 cells

14. IL-17F was produced in peritoneal macrophages after TLR4 activation, peaking after 12 h. This effect was completely dependent on the presence of MyD88. The copresence of the complement activation product C5a amplified IL-17F production.

15. This work demonstrates the important roles of both IL-17 signaling and neutrophils in clearing this pathogen and surviving pulmonary Bacillus anthracis infection.

16. these results suggest the proinflammatory and essential role of IL-17F to develop spontaneous intestinal tumorigenesis in Apc(Min/+) mice in the presence of IL-17A.

17. Data show that Mel-18 and Ezh2 positively regulate the expression of Il17a and Il17f.

18. Increased resistance to infection in a mouse model of tularemia was associated with a specific increase in IL-17A/F

19. IL-17A and IL-17F induce the production of chemokines MCP-1 and MIP-2 via MAPK pathways (p38 MAPK and ERK1/2), as well as mRNA transcription and protein translation and have synergistic effects with TNF-alpha and IL-1beta in cultured mesangial cells.

20. Intranasal administration of adenovirus expressing IL-17F results in bronchoalveolar lavage neutrophilia and inflammatory gene expression in the lung.