Browse our anti-MMP 9 (MMP9) Antibodies

Human Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. MMP-2 (show MMP2 Antibodies) serum level and circulating tumor cells show the potential to predict CNS metastases and overall survival in breast cancer patients; CTCs and MMP-9 serum level could be a promising therapy response marker in castration resistant prostate cancer patients

2. MMP-9 gene promoter was hypomethylated in preterm placenta as compared to term placenta.

3. study provides further evidence to support a core role of the biological activity of MMP-9 in the pathogenesis of pressure ulcer and indicates that the MMP9-1562 C/T (rs 3918242) functional polymorphism is associated with protection against this disease.

4. Prenatal course of metaphyseal anadysplasia associated with homozygous mutation in MMP9 identified by exome sequencing in two siblings has been described.

5. Results document considerable expression of pro-inflammatory CC chemokines and MMP-9 in human monocytes in response to Ureaplasma isolates in vitro.

6. genetic association studies in a population in north India: Data suggest that an SNP in MMP9 genetic promoter region (-1562C>T) is associated with proliferative diabetic retinopathy in type 2 diabetes patients in the population studied.

7. Carriers of MMP9 rs2250889 allele had shorter time to progression (TTP (show ADAMTS13 Antibodies)) of malignant pleural mesothelioma. Carriers of at least one polymorphic MMP9 rs20544 allele had longer TTP (show ADAMTS13 Antibodies).

8. the association study suggests that C1562T and R279Q SNPs of MMP-9 gene can be associated with the susceptibility to myocardial infarction in patients with premature coronary artery disease.

9. MMP-9 and TIMP-2 (show TIMP2 Antibodies) genes are upregulated in cancerous tissues when compared to normal bladder tissues.

10. Studies show that the expression levels of MMP-9 in brain tissue increased after cerebral hemorrhage and related to the prognosis of brain hemorrhage. MMP-9 is related to post-thrombolytic hemorrhagic transformation after cerebral infarction and, aggravates the early brain injury and cerebral vasospasm after subarachnoid hemorrhage. [review]

Mouse (Murine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. analysis of Foxn1 (show FOXN2 Antibodies) and Mmp-9 expression in the intact and postinjured skin of young, adult, and old C57BL/6J and transgenic Foxn1 (show FOXN2 Antibodies)::Egfp mice

2. Diet and exercise affect atheromatous MMP2/9 activity by modulating the systemic inflammatory milieu, with sVCAM-1, resistin, and adiponectin closely interacting with each other and with visceral fat.

3. Myocardial MMP-9 inhibition prevents ventricular arrhythmia through pleiotropic effects, including the modulation of calcium homeostasis and reduced calcium leakage.

4. results first identified the role of SNX10 (show SNX10 Antibodies) in MMP9 trafficking and secretion, and provided an evidence for SNX10 (show SNX10 Antibodies) as a possible therapeutic target for bone destructing disease.

5. Thus, the light reintroduction-induced increase in MMP-9 removes constraints on structural and functional plasticity in the mature cortex.

6. the ZnT3 (show Slc30a3 Antibodies) null state removed synaptic zinc, it rather increased free zinc in the cytosol of brain cells, which appeared to increase MMP-9 activity and BDNF (show BDNF Antibodies) levels. The present results suggest that zinc dyshomeostasis during the critical period of brain development may be a possible contributing mechanism for ASD (show GUSB Antibodies).

7. MMP-9 activation by hypoxia requires LRP1 (show LRP1 Antibodies) and Pyk2 (show PTK2B Antibodies) phosphorylation in fibroblasts.

8. Aneurysmal-prone factors induced HIF-1alpha (show HIF1A Antibodies) can cause overexpression of MMP-2 (show MMP2 Antibodies) and MMP-9 and promote aneurysmal progression.

9. These results demonstrate that OPN (show SPP1 Antibodies) expressed by fatigue-resistant/slow motor neurons is involved in the second-wave neurodegeneration by up-regulating MMP-9 through alphavbeta3 integrin in the mouse model of amyotrophic lateral sclerosis.

10. via binding to hypoxia-responsive elements in MMP9 gene, HIF1alpha (show HIF1A Antibodies) stimulated MMP9 expression, and therefore appeared as a prominent intermediary in HB-EGF (show HBEGF Antibodies)-induced blood-brain barrier damage

Horse (Equine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

Pig (Porcine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. Results provide evidence for the utility of MMP9 and TIMP1 (show TIMP1 Antibodies) as markers of age- and lactocrine-sensitive porcine female reproductive tract development.

2. Increased MMP-9 expression is associated with carotid atherosclerotic plaque.

3. Increased expression of MMP-9 is associated with intraplaque hemorrhage in a swine model of vulnerable carotid atherosclerosis

4. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9, TIMP1 (show TIMP1 Antibodies), and NGAL (show LCN2 Antibodies) (also MMP2 (show MMP2 Antibodies) in 220 kDa complex) without proteolytic activity.

5. Data demonstrate for the first time that MMP2 (show MMP2 Antibodies) and MMP9 are expressed in swine ovarian follicle both in theca and granulosa layers.

6. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 and MMP-2 (show MMP2 Antibodies), caspase-3 (show CASP3 Antibodies) and BDNF (show BDNF Antibodies)

7. Oxygen for newborn resuscitation increases MMP-2 (show MMP2 Antibodies)/-9 activity resulting in tissue damage and influencing remodeling processes.

8. contribution of MMPs to the inflammatory breakdown of the blood-CSF (show CSF2 Antibodies) barrier in vitro

9. The levels of matrix metalloproteinase-2 (show MMP2 Antibodies) and matrix metalloproteinase-9 (MMP-9)in the corpus luteum of swine during luteolysis are reported.

10. Our data define pericyte interactions as a main inducer of endothelial MMP secretion and propose a new role for pericyte-endothelial cell crosstalk at the BBB (show ALMS1 Antibodies) in vitro

Cow (Bovine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. In diabetic retinopathy transcription of MMP-9 is regulated by AP-1 binding at both, proximal and distal sites of its promoter, and acetylation of c-Jun and c-Fos subunits is important in its regulation.

2. These data demonstrate that serum neutrophil haptoglobin (show HP Antibodies)-MMP 9 complexes appear sooner and decline more rapidly than other acute phase proteins.

3. Activation of cytosolic MMP-9 and MMP-2 (show MMP2 Antibodies) was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage.

4. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta (show IL1B Antibodies) mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

5. Decreased MMP-9 and increased TIMP-1 (show TIMP1 Antibodies) expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

6. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (show EGF Antibodies) on MMP-9 and TIMP-1 (show TIMP1 Antibodies) expression by semiquantitative RT-PCR and MMP activity by zymography.

7. results suggest a significant role of matrix metalloproteinase-2 (show MMP2 Antibodies) and-9 in growth and development of bovine follicle

8. Cells constitutively produced proMMP-9 and proMMP-2, and treatment with TNFalpha (show TNF Antibodies), hepatocyte growth factor (show HGF Antibodies), and 12-O-tetradecanoylphorbol 13-acetate resulted in significant increase in level of proMMP-9 but not in level of proMMP-2.

9. MMP-2 and MMP-9 production in blastocysts attached to the endometrial cells is regulated by TNF-alpha and TNF-beta

10. Results suggest that MMP-2 (show MMP2 Antibodies), MMP-9, and TIMP-2 (show TIMP2 Antibodies) mRNAs are expressed in bovine placentomes during the gestational and postpartum periods and that these enzymes, in conjunction with steroidogenic enzymes, mediate fetal membrane detachment after parturition.

Zebrafish Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. Mmp9 is dispensable for Hematopoietic stem cells budding, and is required for proper colonization of secondary niches.

2. The findings of this study suggest that Mmp-9 is a protective molecule against infection by Listeria monocytogenes by engaging in migration of zebrafish macrophages to the site of infection via a non-proteolytic role.

3. elevated beta-oxidation-fuelled mitochondria-derived reactive oxygen species within epidermal cells helps guide matrix metalloproteinase-driven leukocyte recruitment.

4. Mmp9 regulates both acute and chronic tissue damage and plays an essential role in collagen reorganization during wound repair.

5. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 and Mmp13 (show MMP13 Antibodies).

6. study identified mechanism by which mycobacteria induce granulomas: ESAT-6 induced MMP9 in epithelial cells neighboring infected macrophages; MMP9 enhanced recruitment of macrophages, which contributed to nascent granuloma maturation & bacterial growth

7. From 24h post fertilization, mmp9 expression was detected in a population of circulating white blood cells.

8. expression and activity of MMP-2 (show MMP2 Antibodies) and MMP-9 in the embryonic zebrafish.

Xenopus laevis Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. The MMP-9 gene was duplicated and differentiated into two genes, one was specialized in a common ancestor of X. laevis and X. tropicalis expressed in degenerating and remodeling organs in response to thyroid hormone (show PTH Antibodies) during metamorphosis.

2. MMP-9TH is responsible in the larval epithelial apoptosis through degrading ECM (show MMRN1 Antibodies) components in the basal lamina, whereas MMP-9 is involved in the removal of dying epithelial cells during amphibian intestinal remodeling

3. metamorphic tail and intestine RNA levels of TIMP-2 (show TIMP2 Antibodies), MT1-MMP (show MMP14 Antibodies) and Gel-A, but not MT3-MMP (show MMP24 Antibodies) or TIMP-3 (show TIMP3 Antibodies), are elevated during periods of cell death and proliferation

Rabbit Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. Expression of MMP-9 increased after cerebral aneurysm induction, peaking at week 3, leading to reduced smooth muscle cell number, damaged endothelial cells, and damage to the aneurysm wall elastic layer.

2. Inflammatory factors such as TNF-alpha (show TNF Antibodies) can stimulate MMP-2 (show MMP2 Antibodies)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases

3. Therefore, it was reasonable to speculate that the increased expression of VEGF (show VEGFA Antibodies) and MMP-9 in residual hepatic tumor cells and tumor angiogenesis post-embolization would be responsible for the increased metastatic potentiality and invasiveness.

4. Performing minimally invasive surgical procedures in the early stages of intracerebral hemorrhage significantly decreases MMP-9.

5. Increased expression of MMP-9 in spinal cord follows cervical spondylotic myelopathy.

6. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (show MMP2 Antibodies), MMP-9 and TIMP-1 (show TIMP1 Antibodies) in rabbits with acute paraquat poisoning.

7. In experimental syringomyelia, MMP-9 plays an important role in causing edema in the presyrinx state.

8. Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Antibodies) and 9 and increase the expression of PPARgamma (show PPARG Antibodies) in atherosclerotic rabbits.

9. TGF-beta (show TGFB1 Antibodies) mediated MMP-9 induction may be regulated by the NF-kappaB (show NFKB1 Antibodies), Smad3 (show SMAD3 Antibodies), and JNK (show MAPK8 Antibodies) pathways, whereas the IL-1beta (show IL1B Antibodies) mediated induction may be regulated by the NF-kappaB (show NFKB1 Antibodies) and p38 (show MAPK14 Antibodies) pathways.

Guinea Pig Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. The results showed that MMP-2 (show MMP2 Antibodies), MMP-9, and StAR were significantly expressed in the granulosa and thecal cells of the ovarian atretic follicles during proestrus, and were strongly expressed in the corpus luteum during metestrus.