Browse our anti-MMP 9 (MMP9) Antibodies

Human Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. our findings demonstrate that 5-hmC loss is an epigenetic hallmark of hepatocellular carcinoma , and miR (show MLXIP Antibodies)-29a is an important epigenetic modifier, promoting HCC (show FAM126A Antibodies) metastasis through TET-SOCS1 (show SOCS1 Antibodies)-MMP9 axis silencing. The results offer a new strategy for epigenetic cancer therapy

2. Rise in plasma MMP-9 is associated with Chronic lung allograft dysfunction.

3. The authors propose a novel mechanism that involves MMP-9-dependent changes in dendritic spine morphology and the pathophysiology of schizophrenia, providing the first mechanistic insights into the way in which the single base change in the MMP-9 gene (rs20544) influences gene function and results in phenotypic changes observed in schizophrenia patients.

4. The expression of MMP-2 (show MMP2 Antibodies) and MMP-9 is associated with angiogenesis in pancreatic cancer

5. These results suggest that HO-1 (show HMOX1 Antibodies) is involved in oxygen-glucose deprivation-evoked upregulation of apical junctional complex proteins, which is partly mediated by MMP9 pathway.

6. Current findings suggest significant association of MMP9 -1562C>T polymorphism with primary glaucoma in the targeted north Indian population and warrant further replication of the findings in other populations

7. The current study showed a significant association between the MMP9 R279Q G/G polymorphism and formation of glial tumor in advanced age.

8. Zymography assay demonstrated that KLF6 (show KLF6 Antibodies) inhibited the activities of matrix metalloproteinase 9 (MMP-9) and weakened the expression of mesenchymal markers, such as snail (show SNAI1 Antibodies), slug, and vimentin (show VIM Antibodies). Our study is the first to provide demonstrate that KLF6 (show KLF6 Antibodies) functions as a tumor suppressor gene and prevents the metastasis of oral cancer cells.

9. The study suggests a significant association of the MMP-9 rs17576 A/G polymorphism with increased risk of Behcet disease development in Egyptian patients.

10. The presence of TNF-alpha (show TNF Antibodies)-308A allele is associated with increased MMP-9 activity in synovial fluid of patients with early rheumatoid arthritis and may be a predictor of rapid radiographic progression of disease.

Mouse (Murine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. via binding to hypoxia-responsive elements in MMP9 gene, HIF1alpha (show HIF1A Antibodies) stimulated MMP9 expression, and therefore appeared as a prominent intermediary in HB-EGF (show HBEGF Antibodies)-induced blood-brain barrier damage

2. Studied effects of hesperidin on skin photoaging in a hairless mouse model; results showed that hesperidin inhibited the MMP-9 related signaling pathway activated by UVB irradiation.

3. MMP-9 deficiency augmented AngII-induced Abdominal Aortic Aneurysms.

4. Study identifies the tumor suppressor role of epithelial derived-MMP9 in colitis associated cancer via novel mechanistic pathway "MMP9-Notch1 (show NOTCH1 Antibodies)-ARF-p53 (show TP53 Antibodies) axis" regulating apoptosis, cell-cycle arrest and DNA damage.

5. These results show that MMP-9/TIMP-1 (show TIMP1 Antibodies) system disturbance and changes of histological structure in uteri tissue are involved in fluoride-induced reproductive dysfunctions.

6. Synaptic levels of MMP-9 are increased following overexpression of miR (show MLXIP Antibodies)-132 in hippocampal neurons.

7. M. tuberculosis infection caused enhanced MMP-1 (show MMP1 Antibodies), -9, and miR (show MLXIP Antibodies)-223 expression, with inhibited BMAL1 (show ARNTL Antibodies) expression. MiR (show MLXIP Antibodies)-223 modulated BMAL1 (show ARNTL Antibodies) expression via the direct binding of BMAL1 (show ARNTL Antibodies) 3'-UTR (show UTS2R Antibodies).

8. developed a novel selective radiolabeled MMP2 (show MMP2 Antibodies)/9 inhibitor, suitable for single photon emission computed tomography (SPECT) imaging that effectively targets atherosclerotic lesions in mice

9. MMP-2 (show MMP2 Antibodies) and MMP-9 have roles in early stages of experimental autoimmune encephalomyelitis induction; MMP-9 from an immune cell source is required in EAE for initial infiltration of leukocytes into the central nervous system

10. Results show that MMP-9 modulates cholesterol metabolism, at least in part, through a novel MMP-9-plasma secreted phospholipase A2 (show YWHAZ Antibodies) axis that affects the hepatic transcriptional responses to dietary cholesterol. Furthermore, the data suggest that dysregulation of the MMP system can result in metabolic disorder, which could lead to atherosclerosis and coronary heart disease.

Horse (Equine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

Pig (Porcine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. Results provide evidence for the utility of MMP9 and TIMP1 (show TIMP1 Antibodies) as markers of age- and lactocrine-sensitive porcine female reproductive tract development.

2. Increased MMP-9 expression is associated with carotid atherosclerotic plaque.

3. Increased expression of MMP-9 is associated with intraplaque hemorrhage in a swine model of vulnerable carotid atherosclerosis

4. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9, TIMP1 (show TIMP1 Antibodies), and NGAL (show LCN2 Antibodies) (also MMP2 (show MMP2 Antibodies) in 220 kDa complex) without proteolytic activity.

5. Data demonstrate for the first time that MMP2 (show MMP2 Antibodies) and MMP9 are expressed in swine ovarian follicle both in theca and granulosa layers.

6. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 and MMP-2 (show MMP2 Antibodies), caspase-3 (show CASP3 Antibodies) and BDNF (show BDNF Antibodies)

7. Oxygen for newborn resuscitation increases MMP-2 (show MMP2 Antibodies)/-9 activity resulting in tissue damage and influencing remodeling processes.

8. contribution of MMPs to the inflammatory breakdown of the blood-CSF (show CSF2 Antibodies) barrier in vitro

9. The levels of matrix metalloproteinase-2 (show MMP2 Antibodies) and matrix metalloproteinase-9 (MMP-9)in the corpus luteum of swine during luteolysis are reported.

10. Our data define pericyte interactions as a main inducer of endothelial MMP secretion and propose a new role for pericyte-endothelial cell crosstalk at the BBB (show ALMS1 Antibodies) in vitro

Cow (Bovine) Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. In diabetic retinopathy transcription of MMP-9 is regulated by AP-1 binding at both, proximal and distal sites of its promoter, and acetylation of c-Jun and c-Fos subunits is important in its regulation.

2. These data demonstrate that serum neutrophil haptoglobin (show HP Antibodies)-MMP 9 complexes appear sooner and decline more rapidly than other acute phase proteins.

3. Activation of cytosolic MMP-9 and MMP-2 (show MMP2 Antibodies) was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage.

4. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta (show IL1B Antibodies) mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

5. Decreased MMP-9 and increased TIMP-1 (show TIMP1 Antibodies) expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

6. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (show EGF Antibodies) on MMP-9 and TIMP-1 (show TIMP1 Antibodies) expression by semiquantitative RT-PCR and MMP activity by zymography.

7. results suggest a significant role of matrix metalloproteinase-2 (show MMP2 Antibodies) and-9 in growth and development of bovine follicle

8. Cells constitutively produced proMMP-9 and proMMP-2, and treatment with TNFalpha (show TNF Antibodies), hepatocyte growth factor (show HGF Antibodies), and 12-O-tetradecanoylphorbol 13-acetate resulted in significant increase in level of proMMP-9 but not in level of proMMP-2.

9. MMP-2 and MMP-9 production in blastocysts attached to the endometrial cells is regulated by TNF-alpha and TNF-beta

10. Results suggest that MMP-2 (show MMP2 Antibodies), MMP-9, and TIMP-2 (show TIMP2 Antibodies) mRNAs are expressed in bovine placentomes during the gestational and postpartum periods and that these enzymes, in conjunction with steroidogenic enzymes, mediate fetal membrane detachment after parturition.

Zebrafish Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. Mmp9 is dispensable for Hematopoietic stem cells budding, and is required for proper colonization of secondary niches.

2. The findings of this study suggest that Mmp-9 is a protective molecule against infection by Listeria monocytogenes by engaging in migration of zebrafish macrophages to the site of infection via a non-proteolytic role.

3. elevated beta-oxidation-fuelled mitochondria-derived reactive oxygen species within epidermal cells helps guide matrix metalloproteinase-driven leukocyte recruitment.

4. Mmp9 regulates both acute and chronic tissue damage and plays an essential role in collagen reorganization during wound repair.

5. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 and Mmp13 (show MMP13 Antibodies).

6. study identified mechanism by which mycobacteria induce granulomas: ESAT-6 induced MMP9 in epithelial cells neighboring infected macrophages; MMP9 enhanced recruitment of macrophages, which contributed to nascent granuloma maturation & bacterial growth

7. From 24h post fertilization, mmp9 expression was detected in a population of circulating white blood cells.

8. expression and activity of MMP-2 (show MMP2 Antibodies) and MMP-9 in the embryonic zebrafish.

Xenopus laevis Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. The MMP-9 gene was duplicated and differentiated into two genes, one was specialized in a common ancestor of X. laevis and X. tropicalis expressed in degenerating and remodeling organs in response to thyroid hormone (show PTH Antibodies) during metamorphosis.

2. MMP-9TH is responsible in the larval epithelial apoptosis through degrading ECM (show MMRN1 Antibodies) components in the basal lamina, whereas MMP-9 is involved in the removal of dying epithelial cells during amphibian intestinal remodeling

3. metamorphic tail and intestine RNA levels of TIMP-2 (show TIMP2 Antibodies), MT1-MMP (show MMP14 Antibodies) and Gel-A, but not MT3-MMP (show MMP24 Antibodies) or TIMP-3 (show TIMP3 Antibodies), are elevated during periods of cell death and proliferation

Rabbit Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. Expression of MMP-9 increased after cerebral aneurysm induction, peaking at week 3, leading to reduced smooth muscle cell number, damaged endothelial cells, and damage to the aneurysm wall elastic layer.

2. Inflammatory factors such as TNF-alpha (show TNF Antibodies) can stimulate MMP-2 (show MMP2 Antibodies)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases

3. Therefore, it was reasonable to speculate that the increased expression of VEGF (show VEGFA Antibodies) and MMP-9 in residual hepatic tumor cells and tumor angiogenesis post-embolization would be responsible for the increased metastatic potentiality and invasiveness.

4. Performing minimally invasive surgical procedures in the early stages of intracerebral hemorrhage significantly decreases MMP-9.

5. Increased expression of MMP-9 in spinal cord follows cervical spondylotic myelopathy.

6. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (show MMP2 Antibodies), MMP-9 and TIMP-1 (show TIMP1 Antibodies) in rabbits with acute paraquat poisoning.

7. In experimental syringomyelia, MMP-9 plays an important role in causing edema in the presyrinx state.

8. Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Antibodies) and 9 and increase the expression of PPARgamma (show PPARG Antibodies) in atherosclerotic rabbits.

9. TGF-beta (show TGFB1 Antibodies) mediated MMP-9 induction may be regulated by the NF-kappaB (show NFKB1 Antibodies), Smad3 (show SMAD3 Antibodies), and JNK (show MAPK8 Antibodies) pathways, whereas the IL-1beta (show IL1B Antibodies) mediated induction may be regulated by the NF-kappaB (show NFKB1 Antibodies) and p38 (show MAPK14 Antibodies) pathways.

Guinea Pig Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) interaction partners

1. The results showed that MMP-2 (show MMP2 Antibodies), MMP-9, and StAR were significantly expressed in the granulosa and thecal cells of the ovarian atretic follicles during proestrus, and were strongly expressed in the corpus luteum during metestrus.