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NLRP3 Proteins

6 results:

NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-1036) protein (GST tag) Protein

NLRP3 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Pubmed 5
Catalog No. ABIN1312675
$498.33
Plus shipping costs $45.00 and $24.00 dry ice
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-1036) protein (His tag) Protein

Crystallography grade NLRP3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3094146
$15,464.90
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-1033) protein (His tag) Protein

Crystallography grade NLRP3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3136668
$15,464.90
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 671-1033) protein (His tag) Protein

NLRP3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant ≥ 95 % ELISA, IP, SDS, WB
Catalog No. ABIN6238429
$440.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-100) protein (GST tag) Protein

NLRP3 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1312677
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

NLR Family, Pyrin Domain Containing 3 (NLRP3) protein (Fc Tag) Protein

NLRP3 Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN6964301
$433.23
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 27 to 38 Business Days
  • Type Protein
    • Protein
  • Target NLR Family, Pyrin Domain Containing 3 (NLRP3)
    • NLR Family, Pyrin Domain Containing 3 (NLRP3)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase (lipA)
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • SARS-CoV-2 Spike
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Epidermal Growth Factor Receptor (EGFR)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Adenosylhomocysteinase (AHCY)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • SARS-CoV-2 Spike S1
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Thymidine Kinase 1, Soluble (TK1)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Programmed Cell Death 1 (PDCD1)
    • Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1)
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Crystallization (Crys)
    • Immunoprecipitation (IP)
  • Reactivity
    • Human
    • Mouse
  • Cited in publications
  • Images available
  • Preservative free only
  • Host
    • Insect Cells
    • Wheat germ
    • Escherichia coli (E. coli)
    • HEK-293 Cells
  • Binding Specificity
    • AA 1-1036
    • AA 1-100
    • AA 1-1033
    • AA 671-1033
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
    • Fc Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Crystallography grade

NLRP3 Protein Profile

Protein Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Alternative names and synonyms associated with NLRP3

  • NLR family pyrin domain containing-like (NLRPL) antibody
  • NLR family pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 L homeolog (nlrp3.L) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

GENE ID SPECIES
423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta

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