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Full name:: anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 2 Antibodies (DNAJC2)

On www.antibodies-online.com are 50 DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) Antibodies from 18 different suppliers available. Additionally we are shipping DNAJC2 Proteins (11) and and many more products for this protein. A total of 65 DNAJC2 products are currently listed.

Synonyms:: AU020218, MIDA1, MPHOSPH11, MPP11, zgc:85671, Zrf1, Zrf2, ZUO1

list all antibodies	Gene Name	GeneID	UniProt
	DNAJC2	27000	Q99543
	DNAJC2	22791	P54103
	DNAJC2	116456	Q7TQ20
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Most Popular Reactivities for anti-DNAJC2 (DNAJC2) Antibodies

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anti-Human DNAJC2 Antibodies:

anti-Mouse (Murine) DNAJC2 Antibodies:

29 WB Antibodies

anti-Rat (Rattus) DNAJC2 Antibodies:

8 WB Antibodies

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Relevant Pathways for anti-DNAJC2 Antibodies

Chromatin Binding

More product categories related to DNAJC2 Antibody

Top referenced anti-DNAJC2 Antibodies

Human Polyclonal DNAJC2 Primary Antibody for WB - ABIN611292 : Brocke, Chiang, Wagner, Schulman: Functional implications of the subunit composition of neuronal CaM kinase II. in The Journal of biological chemistry 1999 (PubMed)
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Human Polyclonal DNAJC2 Primary Antibody for ICC, IF - ABIN4305618 : de Brito, Giovanelli, Egal, Sánchez-Romero, Nascimento, Martins, Tincani, Del Negro, Gondak, Almeida, Kowalski, Altemani, Mariano: Loss of expression of Plag1 in malignant transformation from pleomorphic adenoma to carcinoma ex pleomorphic adenoma. in Human pathology 2016 (PubMed)
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Human Polyclonal DNAJC2 Primary Antibody for IP, WB - ABIN4305619 : Chitale, Richly: DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair. in Nucleic acids research 2017 (PubMed)

More Antibodies against DNAJC2 Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) interaction partners

These findings suggest that ZRF1 plays a crucial role in tumor malignant potential through its overexpression and highlight its usefulness as a prognostic factor and potential therapeutic target in gastric cancer
Unexplored functions of ZRF1-mediated remodeling in replication and double strand break repair are discussed.
In response to UV irradiation, DICER is recruited to chromatin in a ZRF1-mediated manner. The H2A-ubiquitin binding protein ZRF1 and DICER together impact on the chromatin conformation via PARP1.
ZRF1 mediates remodeling of this E3 ligase complex directly at the DNA lesion site.
The antibody response to ZRF1 was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors.
Zrf1 is transcriptional regulator of neural fate downstream of Id1 in embryonic stem cells.During embryonic stem cell differentiation, Id1 levels decrease allowing Zrf1 to activate neural genes.
our data reveal that ZRF1 is a key transcriptional regulator in leukemia progression
Zrf1 plays an essential role in neural progenitor cell generation and maintenance
ZRF1 regulates the INK4-ARF locus during cellular proliferation and senescence, and alterations in ZRF1 may contribute to tumorigenesis.
the majority of AML patients elicited a humoral immune response against the tumor antigen MPP11
describe a novel epitope derived from the MPP11 antigen that has been recognized by human CD8+ CTL
At the onset of differentiation, ZRF1 specifically displaces polycomb-repressive complex 1 (PRC1) from chromatin and facilitates transcriptional activation
concluded that Mpp11, an ortholog of yeast Zuo, is a ribosome-associated J protein; proposed that in metazoans, ribosome-associated Zuo and Mpp11 orthologs recruit cytosolic Hsc70 to short ribosome-bound nascent chains as they exit the ribosome
MPP11 is localized to the cytosol and with Hsp70L1, forms the mammalian ribosome-associated complex.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) interaction partners

These findings reveal a mechanism by which nutrient sensing pathways impact on cell senescence through the activation of mTORC1-S6 kinases and the phosphorylation of ZRF1.
Zrf1 is identified as a novel regulator of the mesodermal lineage that might facilitate spatiotemporal expression of genes.
Data suggest involvement of MIDA1 in the stimulation of transcription in concert with Hsp70/Hsc70 molecular chaperones.

DNAJC2 Antigen Profile

Antigen Summary

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Alternative names and synonyms associated with DNAJC2

DnaJ heat shock protein family (Hsp40) member C2 (dnajc2) antibody
DnaJ heat shock protein family (Hsp40) member C2 (DNAJC2) antibody
DnaJ heat shock protein family (Hsp40) member C2 (Dnajc2) antibody
DnaJ (Hsp40) homolog, subfamily C, member 2 (dnajc2) antibody

AU020218 antibody
MIDA1 antibody
MPHOSPH11 antibody
MPP11 antibody
zgc:85671 antibody
Zrf1 antibody
Zrf2 antibody
ZUO1 antibody

Protein level used designations for DNAJC2

dnaJ homolog subfamily C member 2 , zuotin related factor 1 , M-phase phosphoprotein 11 , zuotin-related factor 1 , Id associate 1 , zuotin related factor 2 , (rat homolog) mouse id-associated protein 1 , gliosarcoma-related antigen MIDA1

GENE ID	SPECIES
394933	Xenopus (Silurana) tropicalis
417717	Gallus gallus
27000	Homo sapiens
22791	Mus musculus
116456	Rattus norvegicus
507897	Bos taurus
403080	Danio rerio

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Show all anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) Antibodies with Pubmed References

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) interaction partners

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) interaction partners

Antigen Summary

Alternative names and synonyms associated with DNAJC2

Protein level used designations for DNAJC2