Browse our anti-FOXP3 (FOXP3) Antibodies

Zebrafish Forkhead Box P3 (FOXP3) interaction partners

1. analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish

2. correlation between the expression of t-bet, stat6 (show STAT6 Antibodies) and foxp3 with other genes involved in Th and T(reg (show KCNH2 Antibodies)) responses

Atlantic Salmon (Salmo salar) Forkhead Box P3 (FOXP3) interaction partners

1. cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals

Human Forkhead Box P3 (FOXP3) interaction partners

1. Studied lymphocyte phenotype in resected lymph nodes of patients with lung cancer by analyzing levels of Foxp3 and CD8 (show CD8A Antibodies) by immunohistochemical staining.

2. We conclude that Foxp3 promoter polymorphisms are associated with susceptibility to endometrial cancer in Chinese Han women.

3. Studied the association between Foxp3 gene polymorphisms and the susceptibility to differentiated thyroid cancers in a Chinese Han population.

4. DLBCL cases with high FOXP3 have longer survival (P=0.03). T cells in the background of DLBCL may play a role in modulation of tumor progression. Their presence is associated with favorable prognostic parameters in DLBCL

5. no significant association between rs3761548, rs2232365 polymorphisms of the FOXP3 gene, and an increased susceptibility to allergic rhinitis [meta-analysis]

6. Zinc is capable of ameliorating the allogeneic immune reaction by enhancement of antigen-specific iTreg cells due to modulation of essential molecular targets by upregulation of Foxp3 and KLF-10 (show KLF10 Antibodies) and downregulation of IRF-1 (show IRF1 Antibodies).

7. The Foxp3+ regulatory T cells (Tregs) play an indispensable role in controlling tolerance and immunity against self- and foreign antigens.

8. study highlights the role of tissue differentiation on pathological response to neoadjuvant chemotherapy in gastric cancer and shows no impact between FOXP3, HER2 (show ERBB2 Antibodies) and MET expression in terms of tumor regression grading

9. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.

10. FOXP3 genotype association with breast cancer susceptibility and outcome depends on the breast cancer subtype.

Mouse (Murine) Forkhead Box P3 (FOXP3) interaction partners

1. the findings suggested that excreted-secreted antigens restricted Foxp3 expression by inhibiting TGFssRII/Smad2 (show SMAD2 Antibodies)/Smad3 (show SMAD3 Antibodies)/Smad4 (show SMAD4 Antibodies) signalling, ultimately resulting in abortion.

2. Data (including data from studies using transgenic mice) suggest that a single oral dose of vitamin A (1) amplifies tolerogenic activity of dendritic cells migrating to lymphoid tissue and (2) up-regulates expression of Foxp3 and Cd44 (show CD44 Antibodies) in co-cultures of dendritic cells and CD4 (show CD4 Antibodies)+ lymphocytes. (Foxp3 = forkhead box P3; Cd44 (show CD44 Antibodies) = homing receptor)

3. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.

4. Dendritic cells have the capacity to express Foxp3, which can be upregulated by exposure to Staphylococcal enterotoxin B.

5. the Treg transcription factor Foxp3 reprograms T cell metabolism by suppressing Myc (show MYC Antibodies) and glycolysis, enhancing oxidative phosphorylation, and increasing nicotinamide adenine dinucleotide oxidation.

6. Data suggest that genetic or environmental factors that even moderately affect the expression of both PD-1 (show PDCD1 Antibodies) and FoxP3 can cause life-threatening autoimmune diseases by disrupting the T-cell homeostasis.

7. Control of Regulatory T Cell Development by the Transcription Factor Foxp3.

8. Foxp3 Programs the Development and Function of CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)+ Regulatory T Cells.

9. An Essential Role for Scurfin in CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)+ T Regulatory Cells.

10. Mechanistic analysis indicated that E47 (show TCF3 Antibodies) activated expression of the transcription factor Spi-B (show SPIB Antibodies) and the suppressor of cytokine signaling 3 (SOCS3 (show SOCS3 Antibodies)), which both downregulated Foxp3 expression. These findings demonstrate that the balance of Id3 (show ID3 Antibodies) and E47 (show TCF3 Antibodies) controls the maintenance of Foxp3 expression in Treg cells and, thus, contributes to Treg cell plasticity.

Pig (Porcine) Forkhead Box P3 (FOXP3) interaction partners

1. sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids

2. In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection

Cow (Bovine) Forkhead Box P3 (FOXP3) interaction partners

1. GWAS identified a maternal variant in the upstream region of FOXP3 that was associated with infertility in repeat-breeding Japanese Black cattle that failed to conceive using embryo transfer. The variant affected the level of FOXP3 mRNA expression.

2. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 Antibodies).

3. The expression of Foxp3 in CD4 (show CD4 Antibodies)(+) T cells from persistent lymphocytotic cattle was significantly increased.

4. There is a positive correlation between the intensity of CD25 (show IL2RA Antibodies) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A Antibodies)(+) cells.

5. identification of Foxp3 expression in Treg cells

6. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population

Horse (Equine) Forkhead Box P3 (FOXP3) interaction partners

1. The correlation of TH17-related TLR4 (show TLR4 Antibodies) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.

2. Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.

3. results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response