Browse our anti-FOXP3 (FOXP3) Antibodies

Zebrafish Forkhead Box P3 (FOXP3) interaction partners

1. analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish

2. correlation between the expression of t-bet, stat6 (show STAT6 Antibodies) and foxp3 with other genes involved in Th and T(reg (show KCNH2 Antibodies)) responses

Atlantic Salmon (Salmo salar) Forkhead Box P3 (FOXP3) interaction partners

1. cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals

Human Forkhead Box P3 (FOXP3) interaction partners

1. It was concluded that the abnormal expression of endometrial E2A (show TCF3 Antibodies) existed in mid-secretory endometrium of women with recurrent miscarriage, and there was a positive correlation between E2A (show TCF3 Antibodies) and FOXP3, and E2A (show TCF3 Antibodies) and CTLA-4 (show CTLA4 Antibodies), suggesting the possible regulatory role of E2A (show TCF3 Antibodies) in endometrium receptivity.

2. Lymphocytic enteritis associated to celiac disease shows an increase of FOXP3 expression and lymphocytes T-gammadelta that is not detected in other etiologies of enteritis.

3. Downregulated expression of FOXP3 by siRNA transfection significantly inhibited cell proliferation and enhanced chemosensitivity to cisplatin in A549 lung adenocarcinoma cells.

4. Foxp3 is associated with lymphangiogenesis of cervical cancer.

5. Polymorphic marker -3279 C>A of the FOXP3 gene was not associated with the risk of Pulmonary Sarcoidosis patients of Russian ethnicity.

6. Data show that forkhead box P3 protein (show SLC10A3 Antibodies) (FOXP3) protein not only binds with DNA sequences containing one FKH (show FOXA1 Antibodies) consensus sequence, but also binds with DNA sequences with two direct repeats of consensus sequences separated by three-nucleotides (DRE3).

7. Study identifies CCR8 (show CCR8 Antibodies)+ regulatory T cells (Treg cells) as drivers of immunosuppression and provides compelling evidence of a self-feeding mechanism by which, at an autoimmune site, CCL1 (show CCL1 Antibodies) produced by FOXp3+ Treg cells upregulates the expression of its own receptor, CCR8 (show CCR8 Antibodies), on these cells, and potentiates their in vivo proliferation and suppressive activities as driver Treg cells.

8. our findings suggest that FOXP3 suppresses tumor progression in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) via TGF-b/Smad2 (show SMAD2 Antibodies)/3 signaling pathway, highlighting the role of FOXP3 as a prognostic factor and novel target for an optimal therapy against this fatal malignancy

9. Studied lymphocyte phenotype in resected lymph nodes of patients with lung cancer by analyzing levels of Foxp3 and CD8 (show CD8A Antibodies) by immunohistochemical staining.

10. We conclude that Foxp3 promoter polymorphisms are associated with susceptibility to endometrial cancer in Chinese Han women.

Mouse (Murine) Forkhead Box P3 (FOXP3) interaction partners

1. Unexpectedly, although dispensable for FOXP3 expression and for the homeostasis and suppressive function of thymus-derived Treg cells, CREB (show CREB1 Antibodies) negatively regulates the survival of TGF-beta (show TGFB1 Antibodies)-induced Treg cells, and deletion of CREB (show CREB1 Antibodies) resulted in increased FOXP3+ Treg cells in the intestine and protection in a colitis model

2. This study reports on systematic alanine-scan mutagenesis of FoxP3, assessing mutational impacts on DNA binding and transcriptional activation or repression.

3. Foxp3 is essential for beneficial outcome of the microglial response and depends upon signalling by the immunoglobulin CD200 (show CD200 Antibodies) through its receptor (CD200R (show CD200R1 Antibodies))

4. Tbet is a critical modulator of FoxP3 expression in autoimmune graft-versus-host disease

5. Generation of RORgammat(+) antigen-specific T17 regulatory cells from Foxp3(+) precursors in autoimmunity has been described.

6. KLRG1 (show KLRG1 Antibodies) expression identifies short-lived Foxp3(+) Treg effector cells with functional plasticity in islets of NOD mice.

7. Novel regulatory T-cells that are induced by B cells and do not express Foxp3 and IL-10 (show IL10 Antibodies) alleviate intestinal inflammation in vivo.

8. the findings suggested that excreted-secreted antigens restricted Foxp3 expression by inhibiting TGFssRII/Smad2 (show SMAD2 Antibodies)/Smad3 (show SMAD3 Antibodies)/Smad4 (show SMAD4 Antibodies) signalling, ultimately resulting in abortion.

9. Data (including data from studies using transgenic mice) suggest that a single oral dose of vitamin A (1) amplifies tolerogenic activity of dendritic cells migrating to lymphoid tissue and (2) up-regulates expression of Foxp3 and Cd44 (show CD44 Antibodies) in co-cultures of dendritic cells and CD4 (show CD4 Antibodies)+ lymphocytes. (Foxp3 = forkhead box P3; Cd44 (show CD44 Antibodies) = homing receptor)

10. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.

Pig (Porcine) Forkhead Box P3 (FOXP3) interaction partners

1. sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids

2. In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection

Cow (Bovine) Forkhead Box P3 (FOXP3) interaction partners

1. GWAS identified a maternal variant in the upstream region of FOXP3 that was associated with infertility in repeat-breeding Japanese Black cattle that failed to conceive using embryo transfer. The variant affected the level of FOXP3 mRNA expression.

2. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 Antibodies).

3. The expression of Foxp3 in CD4 (show CD4 Antibodies)(+) T cells from persistent lymphocytotic cattle was significantly increased.

4. There is a positive correlation between the intensity of CD25 (show IL2RA Antibodies) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A Antibodies)(+) cells.

5. identification of Foxp3 expression in Treg cells

6. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population

Horse (Equine) Forkhead Box P3 (FOXP3) interaction partners

1. The correlation of TH17-related TLR4 (show TLR4 Antibodies) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.

2. Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.

3. results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response