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anti-Human KIAA0101 Antibodies:
anti-Rat (Rattus) KIAA0101 Antibodies:
anti-Mouse (Murine) KIAA0101 Antibodies:
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Human Monoclonal KIAA0101 Primary Antibody for IF, IHC (p) - ABIN564218
Yuan, Jeng, Pan, Hu, Lai, Lee, Hsu: Overexpression of KIAA0101 predicts high stage, early tumor recurrence, and poor prognosis of hepatocellular carcinoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Show all 6 Pubmed References
Human Polyclonal KIAA0101 Primary Antibody for WB - ABIN4894629
Liu, Liu, Chen, Wang, Zhou, Zhou, Li, Zhu: Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma. in Oncotarget 1970
our biochemical data show that p15PAF impairs primer synthesis by pol eta-PCNA holoenzyme against both damaged and normal DNA templates. In light of our findings, we discuss the possible mechanistic roles of p15PAF in DNA replication and suppression of DNA lesion bypass.
MiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF
Data demonstrated that NDRG1 is critical for mediating LANA to recruit PCNA onto terminal repeat (TR) of KSHV genome, and facilitates viral DNA replication and episome persistence. Findings suggest that NDRG1 plays an important role in KSHV viral genome replication, and provide new clues for understanding of KSHV persistence.
KIAA0101 was closely related to the FOXM1 and PI3K/AKT/mTOR signaling pathways.
These results suggested that KIAA0101 knockdown suppressed the cell proliferation and cell cycle progression by promoting the formation of p53/Sp1 complex in breast cancer.
PAF supports glioma stem cells maintenance, in part, by influencing DNA replication and pyrimidine metabolism pathways.PAF-associated DNA translesion synthesis activity influences glioma stem cell radiation resistance.
KIAA0101 tv2 exerts anti-tumor activity in HCC and acts as an endogenous competitor of tumor-associated KIAA0101 tv1. KIAA0101 tv2 has a potential to work as a therapeutic drug targeting the KIAA0101 tv1 in HCC.
Paf15 expression is associated with increased rectal cancer proliferation, decreased patient survival, and a worse radiotherapeutic response
High KIAA0101 expression is associated with kidney cancer.
The complex between p15PAF and trimeric PCNA is of low affinity, forming a transient complex that is difficult to characterize at a structural level due to its inherent polydispersity. We have determined the structure, conformational fluctuations, and relative population of the five species that coexist in solution by combining small-angle X-ray scattering (SAXS) with molecular modelling.
miR-429 mediates deregulation of KIAA0101 by acting as an anti-metastatic miRNA that targets KIAA0101 pro-metastatic gene during metastasis of soft tissue sarcomas
PAF stimulation dose-dependently promoted the invasion, migration and growth of prostate cancer cells in vitro, while knockdow our findings demonstrate that PAFR can activate ERK1/2 pathway, and subsequently increase MMP-3 expression and decrease E-cadherin expression
High KIAA0101 level is associated with metastasis in hepatocellular carcinoma.
Results unveil an unsuspected role of the PAF-Wnt signalling axis in modulating cell plasticity, which is required for the maintenance of breast cancer cell stemness.
Results indicated that the expression of NS5ATP9 was up-regulated by starvation and that Beclin 1 was involved in autophagy induced in hepatoblastoma cells by starvation.
IN PATIENTS WITH HEPATITIS C VIRUS GENOTYPE 1B, TREATMENT RESPONSE WITH DACLATASVIR PLUS ASUNAPREVIR WITHOUT NS5A-L31F/I/M/V and/or NS5A-Y93H polymorphisms
p15PAF acts as a flexible drag that regulates PCNA sliding along the DNA and facilitates the switch from replicative to translesion synthesis polymerase binding.
Data show that hepatitis C virus NS5A-transactivated protein 9 (NS5ATP9) knockdown activated mitogen-activated protein kinase kinase/extracellular signal regulated kinases 1/2 signaling under C virus nonstructural protein 5A (NS5A) expression.
NS5ATP9 mRNA overexpression in peripheral blood mononuclear cells was significantly associated with poor disease-free survival and overall survival of gastric cancer patients, but not with tumor recurrence.
These results highlight an important potential role for NS5ATP9 in hepatitis C virus NS5A-induced hepatocyte autophagy.
UHRF1 ubiquitinates PAF15 at Lys 15 and Lys 24 and promotes its binding to PCNA during late S-phase
PAF-induced ductal epithelial cell hyperproliferation was accompanied by extracellular signal-regulated kinase (ERK) phosphorylation independently of Ras or Raf mutations.
Paf as a novel and essential regulator of early hematopoiesis.
highly restricted expression of the p15(PAF) gene in a spatio-temporal manner during embryogenesis
May be involved in protection of cells from UV-induced cell death.
HCV NS5A-transactivated protein 9
, PCNA-associated factor
, PCNA-associated factor of 15 kDa
, hepatitis C virus NS5A-transactivated protein 9
, overexpressed in anaplastic thyroid carcinoma 1
, uncharacterized protein LOC496365
, PCNA-associated factor-like
, HCV NS5A-transactivated protein 9 homolog