Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Worldwide Shipping!
Find out more »
Show all species
Show all synonyms
Select your species and application
anti-Human MBD2 Antibodies:
anti-Mouse (Murine) MBD2 Antibodies:
anti-Rat (Rattus) MBD2 Antibodies:
Go to our pre-filtered search.
Human Polyclonal MBD2 Primary Antibody for IF, WB - ABIN1881531 : Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010 (PubMed) Show all 3 Pubmed References
Human Polyclonal MBD2 Primary Antibody for IHC (p), IHC - ABIN188691 : Tan, Nakielny: Control of the DNA methylation system component MBD2 by protein arginine methylation. in Molecular and cellular biology 2006 (PubMed) Show all 2 Pubmed References
Human Polyclonal MBD2 Primary Antibody for GS, WB - ABIN151224 : Ballestar, Paz, Valle, Wei, Fraga, Espada, Cigudosa, Huang, Esteller: Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. in The EMBO journal 2003 (PubMed) Show all 2 Pubmed References
Human Polyclonal MBD2 Primary Antibody for ICC, IF - ABIN257102 : Kim, Kwak, Weitz: Specificity in circadian clock feedback from targeted reconstitution of the NuRD corepressor. in Molecular cell 2014 (PubMed)
Human Polyclonal MBD2 Primary Antibody for IHC, ELISA - ABIN334432 : Auriol, Billard, Magdinier, Dante: Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus. in Nucleic acids research 2005 (PubMed) Show all 2 Pubmed References
Human Polyclonal MBD2 Primary Antibody for IHC, WB - ABIN2779675 : Xing, Stewart, Gu, Lu, Spitz, Wu: Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer. in British journal of cancer 2008 (PubMed) Show all 2 Pubmed References
CpG and methylation-dependent DNA binding and dynamics of the MBD2 (show DPEP2 Antibodies) protein at the single-molecule level have been reported.
Results show that MBD2 (show DPEP2 Antibodies) mediates epigenetic silencing of Htra1 (show HTRA1 Antibodies).
MBD2 (show DPEP2 Antibodies) has a critical role in 'rewriting' the cancer methylome at specific regulatory regions.
MBD2 (show DPEP2 Antibodies) expression was elevated in HCC (show FAM126A Antibodies) tissue, which suggesting MBD2 (show DPEP2 Antibodies) as a candidate prognostic marker of HCC (show FAM126A Antibodies).
downregulation of miR (show MLXIP Antibodies)-221 inhibits cell migration and invasion at least partially through targeting MBD2 (show DPEP2 Antibodies) in the human OSCC cell line UM1.
Specifically, methyl-CpG-binding domain protein 2 (MBD2) is revealed to be recruited to DNA damage sites after laser microirradiation, which was mediated through MBD (show DPEP1 Antibodies) domain and MBD2 (show DPEP2 Antibodies) C-terminus.
MBD2 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.
The dynamics of MBD2 (show DPEP2 Antibodies) deposition across methylated DNA regions was associated with the oncogenic transformation of human mammary cells.
Data suggest that MBD2 (show DPEP2 Antibodies) binds primarily at highly methylated regions, with a strong preference for CpG islands and highlights that MBD2 (show DPEP2 Antibodies) binding sites display increased methylation in primary breast cancer tissues as compared to normal mammary cells.
Biophysical analyses show that the MBD2IDR is an intrinsically disordered region (IDR). However, despite this inherent disorder, MBD2IDR increases the overall binding affinity of MBD2 (show DPEP2 Antibodies) for methylated DNA.
It has been shown that chromatin localization of Mbd2 and Mbd3 (show MBD3 Antibodies) is highly overlapping, and both proteins are interdependent for chromatin association.
MBD2 has a critical role in 'rewriting' the cancer methylome at specific regulatory regions.
Loss of Mbd2 resulted in impaired implementation of above DNA methylation (show HELLS Antibodies) changes associated with altered energy homeostasis, which then protected mice from HFD-induced obesity and insulin (show INS Antibodies) resistance.
Mbd2 has a key role regulating expression of a range of genes that are associated with optimal dendritic cell activation and function.
methyl-CpG-binding domain protein 2 (MBD2), an epigenetic regulator, controls autoimmunity and EAE through T-bet/Hlx (show HLX Antibodies).
Biophysical analyses show that the MBD2IDR is an intrinsically disordered region (IDR). However, despite this inherent disorder, MBD2IDR increases the overall binding affinity of MBD2 for methylated DNA.
miR (show MLXIP Antibodies)-290/371-Mbd2-Myc (show MYC Antibodies) circuit regulates glycolytic metabolism to promote pluripotency.
these findings suggest that CpG methylation and MBD2 are involved in altering Scn3a (show SCN3A Antibodies) expression during postnatal development and seizure condition.
Data suggest that methyl-CpG binding domain protein 2 (MBD2) gene knockout may lead to accumulation of more deposits on the Bruch's membrane (BM) and influence the pathogenesis of age-related macular degeneration (AMD (show AMD1 Antibodies)).
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.
methyl-CpG binding domain protein 2 , demethylase , methyl-CpG-binding domain protein 2 , methyl-CpG-binding protein MBD2 , methyl-CpG binding protein MBD2