anti-MBD2 Antibodies

Protein Summary

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MBD2

• methyl-CpG binding domain protein 2 (MBD2) antibody
• methyl-CpG binding domain protein 2 (Mbd2) antibody
• methyl-CpG binding domain protein 2 (mbd2) antibody
• methyl-CpG binding domain protein 2 S homeolog (mbd2.S) antibody

• DMTase antibody
• MBD2 antibody
• MBD2a antibody
• NY-CO-41 antibody
• wu:fa97f06 antibody
• Show all synonym aliases
• zgc:111862 antibody

Protein level used designations for MBD2

methyl-CpG binding domain protein 2 , demethylase , methyl-CpG-binding domain protein 2 , methyl-CpG-binding protein MBD2 , methyl-CpG binding protein MBD2