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COX2 Products

(Cytochrome C Oxidase Subunit II (COX2))
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009].

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Featured COX2 Categories

COX2 Antibodies

High quality antibodies with extensive validation data.

COX2 ELISA Kits

Reliable ELISA kits for a wide range of species.

COX2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COX2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7445771
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7266639
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7149158
Quantity 100 μg
Datasheet Datasheet

Recommended COX2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962698
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955215
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN6955216
Quantity 96 tests
Datasheet Datasheet

Recommended COX2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122571
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423849
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3111472
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our COX2 products

Zhang, Xu, Liu, Lv, Hu, Wang, Li, Wang, Ji, Ma, Wang, Wang: "Dietary Supplementation of Foxtail Millet Ameliorates Colitis-Associated Colorectal Cancer in Mice via Activation of Gut Receptors and Suppression of the STAT3 Pathway." in: Nutrients, Vol. 12, Issue 8, (2020) (PubMed).

Ilievska, Dinevska-Kjovkarovska, Miova: "Effect of single and repeated heat stress on chemical signals of heat shock response cascade in the rat's heart." in: Cell stress & chaperones, Vol. 23, Issue 4, pp. 561-570, (2019) (PubMed).

Altieri, Bertolotto, Fabbi, Sportelli, Balbi, Santini, Brunelli, Canepa, Montecucco, Ameri: "Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects." in: International journal of cardiology, Vol. 271, pp. 219-227, (2019) (PubMed).

Velusami, Richard, Bethapudi: "Polar extract of Curcuma longa protects cartilage homeostasis: possible mechanism of action." in: Inflammopharmacology, Vol. 26, Issue 5, pp. 1233-1243, (2019) (PubMed).

Cholet, Decombat, Vareille-Delarbre, Gainche, Berry, Senejoux, Ripoche, Delort, Vermerie, Fraisse, Felgines, Ranouille, Berthon, Priam, Saunier, Tourrette, Troin, Thebaud, Chalard, Caldefie-Chezet: "In Vitro Anti-Inflammatory and Immunomodulatory Activities of an Extract from the Roots of Bupleurum rotundifolium." in: Medicines (Basel, Switzerland), Vol. 6, Issue 4, (2019) (PubMed).

Mirahmadi, Shahmohammadi, Rousta, Azadi, Fahanik-Babaei, Baluchnejadmojarad, Roghani: "Soy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects." in: Cytokine, Vol. 104, pp. 151-159, (2018) (PubMed).

Yang, Wei, Song, Cai, Zhou, Peng, Jiang, Peng: "E4BP4 mediates glucocorticoid-regulated adipogenesis through COX2." in: Molecular and cellular endocrinology, Vol. 450, pp. 43-53, (2018) (PubMed).

Zhou, Qin, Li, Li, Wang, Zhang, Chen, Li: "Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 115, (2018) (PubMed).

Li, Zhou, Li, Li, Long, Chen, Zhang, Li, Feng: "WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity." in: Free radical biology & medicine, (2018) (PubMed).

Sun, Li, Li, Yang, Zhang, Huang: "Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12." in: Acta pharmacologica Sinica, Vol. 38, Issue 6, pp. 806-822, (2018) (PubMed).

Synonyms and alternative names related to COX2

prostaglandin-endoperoxide synthase 2 (Ptgs2), cytochrome c oxidase subunit II (COX2), COXII (COX2), cytochrome c oxidase subunit II (Smed_0518), cytochrome c oxidase subunit II (Mrub_0709), cytochrome c oxidase subunit ii (Ocepr_1683), cytochrome c oxidase subunit II (SCO2156), cytochrome c oxidase subunit II (coxB), cytochrome c oxidase subunit II (Dtpsy_2860), cytochrome C oxidase subunit II (Ndas_3150), cytochrome c oxidase subunit II (Mesil_0628), cytochrome C oxidase subunit II (Bresu_0801), cytochrome c oxidase subunit 2 (cox2), cytochrome oxidase subunit 2 (COX2), cCOII, COII, cox, COX-2, Cox2, MTCO2, SC6G10.29c

Protein level used designations for COX2

  • PGH synthase 2
  • PGHS-2
  • PHS II
  • cyclooxygenase 2
  • cyclooxygenase-2
  • prostaglandin G/H synthase 2
  • prostaglandin H2 synthase 2
  • cytochrome c oxidase subunit II
  • cytochrome c oxidase subunit ii
  • cytochrome C oxidase subunit II
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