Browse our anti-C1QC (C1QC) Antibodies

Full name:: anti-Complement Component 1, Q Subcomponent, C Chain Antibodies (C1QC)

On www.antibodies-online.com are 66 Complement Component 1, Q Subcomponent, C Chain (C1QC) Antibodies from 15 different suppliers available. Additionally we are shipping C1QC Kits (16) and C1QC Proteins (6) and many more products for this protein. A total of 95 C1QC products are currently listed.

Synonyms:: AI385742, C1Q-C, c1qc, C1QG, Ciqc

list all antibodies	Gene Name	GeneID	UniProt
	C1QC	12262	Q02105
	C1QC	362634	P31722
	C1QC	714	P02747
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Relevant Pathways for anti-C1QC Antibodies

Complement System

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Mouse (Murine) Complement Component 1, Q Subcomponent, C Chain (C1QC) interaction partners

Human Complement Component 1, Q Subcomponent, C Chain (C1QC) interaction partners

Neuromyelitis optica patients had higher levels of C3a (show C3 Antibodies) and anti-C1q antibodies than healthy controls.
Data indicate that Cna (show CAN Antibodies) binds to C1q.
Analysis of its interaction properties by surface plasmon resonance shows that rC1q retains the ability of serum C1q to associate with the C1s (show C1S Antibodies)-C1r-C1r (show C1R Antibodies)-C1s (show C1S Antibodies) tetramer, to recognize physiological C1q ligands such as IgG and pentraxin 3 (show PTX3 Antibodies)
Single nucleotide polymorphisms in and around the C1q genes, C1qA (show C1QA Antibodies), C1qB (show C1QB Antibodies) and C1qC, correlated with C1q serum levels and may be a risk for the development of rheumatoid arthritis.
Three single nucleotide polymorphisms (STAT6 (show STAT6 Antibodies) rs703817, C1qG rs17433222, and MBP (show MBL2 Antibodies) rs3794845) were found to be significantly associated with childhood leukemia risk in Koreans.
These results suggest a novel pathway in which C1q and MBL influence removal and metabolism of atherogenic forms of LDL in the early stages of atherosclerosis.
Data show that C1q, C4, C3, and C9 bind to thrombin receptor (show F2R Antibodies)-activating peptide-activated platelets in lepirudin-anticoagulated platelet-rich plasma (PRP (show C4BPA Antibodies)) and whole blood.
Experiments with recombinant globular head domains of human C1q A, B, and C chains indicated that C1q interacts with PTX3 (show PITX3 Antibodies) via its globular head region. Binding of C1q to immobilized PTX3 (show PITX3 Antibodies) induced activation of the classical complement pathway.
The C-terminal globular region of the C1Q C chain may have evolved as a functionally specialized domain or module with distinct binding properties which together with the A and B chains confers versatility and flexibility to the whole C1q molecule.
The structure refined to 1.9 A of resolution of C1q reveals the conformation of subunits A, B, and C and their compact, almost spherical heterotrimeric assembly held together mainly by non-polar interactions, with a Ca2 (show CA2 Antibodies)+ ion bound at the top.

C1QC Antigen Profile

Antigen Summary

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Alternative names and synonyms associated with C1QC

complement C1q C chain (C1QC) antibody
complement component 1, q subcomponent, C chain (c1qc) antibody
complement component 1, q subcomponent, C chain (C1qc) antibody
complement C1q C chain (C1qc) antibody

AI385742 antibody
C1Q-C antibody
c1qc antibody
C1QG antibody
Ciqc antibody

Protein level used designations for C1QC

complement component 1, q subcomponent, C chain , complement C1q subcomponent subunit C , Complement C1q subcomponent subunit C , complement component 1, q subcomponent, c polypeptide , complement component 1, q subcomponent, gamma polypeptide

GENE ID	SPECIES
419503	Gallus gallus
487382	Canis lupus familiaris
509968	Bos taurus
100196757	Salmo salar
12262	Mus musculus
362634	Rattus norvegicus
714	Homo sapiens

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