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Together, our results suggest that KLF4 (show KLF4 Proteins) regulates asthma development in a TSLP (show TSLP Proteins)- and fibrocyte-dependent manner.
Pronounced correlations between KLK10 (show KLK10 Proteins)/KLK11 (rs = 0.647) and between KLK9 (show KLK9 Proteins)/KLK15 (show KLK15 Proteins) (rs = 0.716) mRNA, but not between other combinations, indicate coordinate expression of distinct pairs of peptidases
Variations in KLK15 (show KLK15 Proteins), but not KLK11 expression were significantly associated with prognosis in gastric cancer
KLK11 mRNA expression could be considered as a new molecular prognostic biomarker in colorectal adenocarcinoma
hK11 expression in gastric cancer appears to be associated with a better prognosis. hK11 may be a prognostic biomarker of gastric cancer.
The aim of this study was to monitor serum levels of two microRNAs (miR-21 and miR-141) and three kallikreins (hK3/PSA, hK11, and hK13) before and 1, 5, and 30 days after radical prostatectomy.
Our data showed that UVB-induced TSLP (show TSLP Proteins) might increase secretion of the T-helper type 2-attracting chemokine (c-c motif) ligand 17 (show CCL17 Proteins) by human dendritic cells.
HOXB8 (show HOXB8 Proteins) and KLK11 may be classified as valuable biomarkers, as they can predict the effects of FOLFOX4 chemotherapy in primary advanced colorectal cancer patients
Human airway trypsin-like protease (show TMPRSS11D Proteins) can stimulate mucin5AC hypersecretion through a PAR2 (show F2RL1 Proteins)-mediated signaling pathway in 16HBE cells.
Patients harboring KLK11-positive tumors had a significantly decreased risk of death.
Low KLK11 protein expression is associated with gastric cancer.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
kallikrein-related peptidase 11
, kallikrein 11
, protease, serine, 20
, serine protease 20
, trypsin-like protease