Browse our anti-Kallikrein 4 (KLK4) Antibodies

Full name:: anti-Kallikrein-Related Peptidase 4 Antibodies (KLK4)

On www.antibodies-online.com are 83 Kallikrein-Related Peptidase 4 (KLK4) Antibodies from 21 different suppliers available. Additionally we are shipping Kallikrein 4 Proteins (26) and Kallikrein 4 Kits (24) and many more products for this protein. A total of 138 Kallikrein 4 products are currently listed.

Synonyms:: AI2A1, ARM1, EMSP, Emsp1, ESMP1, kallikrein, KLK-L1, PRSS17, PSTS

list all antibodies	Gene Name	GeneID	UniProt
	KLK4	56640
	KLK4	9622	Q9Y5K2
	KLK4	408210
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Most Popular Reactivities for anti-Kallikrein 4 (KLK4) Antibodies

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anti-Mouse (Murine) Kallikrein 4 Antibodies:

14 WB Antibodies

anti-Human Kallikrein 4 Antibodies:

anti-Rat (Rattus) Kallikrein 4 Antibodies:

9 WB Antibodies

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Relevant Pathways for anti-Kallikrein 4 Antibodies

Complement System

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More Antibodies against Kallikrein 4 Interaction Partners

Mouse (Murine) Kallikrein-Related Peptidase 4 (KLK4) interaction partners

normal enamel maturation is regulated by TGF-ss signaling through the expression of KLK4
The breakage of enamel near the dentino-enamel junction in Klk4-null mice is not due to a failure of odontoblasts to express Klk4, but it relates to a progressive hypomineralization of enamel with depth.
Effect of kallikrein 4 loss on enamel mineralization: comparison with mice lacking matrix metalloproteinase 20 (show MMP20 Antibodies).
expression of KLK4 correlates with the stage-associated changes in the digestion of enamel proteins
Mice lacking expression of the AmelX (show AMELX Antibodies), Enam (show ENAM Antibodies) and Mmp20 (show MMP20 Antibodies) genes have been generated.
Dipeptidyl peptidase I (show CTSC Antibodies) activates pro-KLK4 to cleave a fluorogenic peptide containing a KLK4 cleavage site in mice incisor enamel organs during amelogenesis. site.
Klk4 is essential for the removal of enamel proteins and the proper maturation of enamel crystals in mice

Human Kallikrein-Related Peptidase 4 (KLK4) interaction partners

During the descriptive analysis, the variables ethnicity, biofilm, and gingivitis and the markers rs2242670 and rs2978642 were statistically significant. In the multivariate analysis, the marker rs2242670 and the variable biofilm maintained statistical significance. Genetic variations in the KLK4 gene may contribute to dental decay.
Epithelial-derived KLK4 promotes tumour progression by actively promoting cancer-associated fibroblasts differentiation in the prostate stromal microenvironment.
structural analysis of mechanism of KLK4 inhibition
These findings prompt a new mechanistic model and line of enquiry into the role of KLK4 in enamel hardening and malformation.
Results show that AMTN and KLK4 are not essential for biological processes outside of the dentition or during the secretory stage of amelogenesis. Both KLK4 and AMTN proved to be essential for the maturation of dental enamel, a process that requires the removal of extracellularmatrix proteins and the deposition of ions on the sides of enamel crystallites.
The KLK4 protein is localized in the cytoplasm of tumor and stroma cells.
KLK4 as a potential multifunctional regulator of prostate cancer progression.
Low KLK4 expression is associated with lupus nephritis.
KLK4 may contribute to the metastasis of OSCC through the PI3 K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathway
KLK4 acts as an oncogene (show RAB1A Antibodies) in OSCC cells, and targeting KLK4 may be a promising method for OSCC therapy.

Kallikrein 4 (KLK4) Antigen Profile

Antigen Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined.

Alternative names and synonyms associated with Kallikrein 4 (KLK4)

kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) (Klk4) antibody
kallikrein related peptidase 4 (KLK4) antibody
kallikrein-related peptidase 4 (Klk4) antibody

AI2A1 antibody
ARM1 antibody
EMSP antibody
Emsp1 antibody
ESMP1 antibody
kallikrein antibody
KLK-L1 antibody
PRSS17 antibody
PSTS antibody

Protein level used designations for KLK4

kallikrein 4 (prostase, enamel matrix, prostate) , kallikrein-4 , protease, serine 17 (enamel matrix, prostate) , androgen-regulated message 1 , enamel matrix serine protease 1 , enamel matrix serine proteinase 1 , kallikrein-like protein 1 , prostase , serine protease 17 , Enamel matrix serine proteinase 1

GENE ID	SPECIES
56640	Mus musculus
9622	Homo sapiens
408210	Rattus norvegicus

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