Browse our anti-Integrin alpha 2 (ITGA2) Antibodies

Full name:: anti-Integrin alpha 2 Antibodies (ITGA2)

On www.antibodies-online.com are 464 Integrin alpha 2 (ITGA2) Antibodies from 27 different suppliers available. Additionally we are shipping Integrin alpha 2 Kits (16) and Integrin alpha 2 Proteins (11) and many more products for this protein. A total of 495 Integrin alpha 2 products are currently listed.

Synonyms:: BR, CD49B, DX5, GPIa, HPA-5, VLA-2, VLAA2

list all antibodies	Gene Name	GeneID	UniProt
	ITGA2	3673	P17301
	ITGA2	16398	Q62469
	ITGA2	170921
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Relevant Pathways for anti-Integrin alpha 2 Antibodies

Integrin Complex

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Top referenced anti-Integrin alpha 2 Antibodies

Human Monoclonal ITGA2 Primary Antibody for CyTOF, FACS - ABIN4900791 : Kamata, Takada: Direct binding of collagen to the I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner. in The Journal of biological chemistry 1994 (PubMed)
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Mouse (Murine) Monoclonal ITGA2 Primary Antibody for BR, FACS - ABIN1176973 : Arase, Saito, Phillips, Lanier: Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
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Mouse (Murine) Monoclonal ITGA2 Primary Antibody for BR, FACS - ABIN2689302 : Chen, Paul: A population of CD62Llow Nk1.1- CD4+ T cells that resembles NK1.1+ CD4+ T cells. in European journal of immunology 1998 (PubMed)
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Mouse (Murine) Monoclonal ITGA2 Primary Antibody for CyTox, IHC (fro) - ABIN2689301 : Moore, von Freeden-Jeffry, Murray, Zlotnik: Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice. in Journal of immunology (Baltimore, Md. : 1950) 1996 (PubMed)
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Human Monoclonal ITGA2 Primary Antibody for FACS, IP - ABIN2480690 : Katayama: [Basic and experimental studies of the renin-angiotensin-aldosterone system in diabetes mellitus]. in Nihon Naibunpi Gakkai zasshi 1991 (PubMed)
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Mouse (Murine) Monoclonal ITGA2 Primary Antibody for IHC (fro), FACS - ABIN2689298 : Ortaldo, Winkler-Pickett, Mason, Mason: The Ly-49 family: regulation of cytotoxicity and cytokine production in murine CD3+ cells. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
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Mouse (Murine) Monoclonal ITGA2 Primary Antibody for BR, IHC (fro) - ABIN2689303 : Hemler: VLA proteins in the integrin family: structures, functions, and their role on leukocytes. in Annual review of immunology 1990 (PubMed)
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Baboon Monoclonal ITGA2 Primary Antibody for FACS - ABIN2480695 : Weinstein, Golding: Temporary external shunt bypass in the traumatically amputated upper extremity. in The Journal of trauma 1976 (PubMed)
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Baboon Monoclonal ITGA2 Primary Antibody for FACS - ABIN2480697 : Mazurov, Vinogradov, Kabaeva, Antonova, Romanov, Vlasik, Antonov, Smirnov: A monoclonal antibody, VM64, reacts with a 130 kDa glycoprotein common to platelets and endothelial cells: heterogeneity in antibody binding to human aortic endothelial cells. in Thrombosis and haemostasis 1992 (PubMed)
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Mouse (Murine) Monoclonal ITGA2 Primary Antibody for FACS - ABIN2480704 : Lin, Chuang, Liao, Huang, Pai, Chu: Combined immunogene therapy of IL-6 and IL-15 enhances anti-tumor activity through augmented NK cytotoxicity. in Cancer letters 2008 (PubMed)

More Antibodies against Integrin alpha 2 Interaction Partners

Human Integrin alpha 2 (ITGA2) interaction partners

Carriage of a combination of mutant alleles in multiple genes including ITGB3 (show ITGB3 Antibodies)+CYP2C19 (show CYP2C19 Antibodies)*2 or CYP2C19 (show CYP2C19 Antibodies)*2 + ITGA2 or CYP2C19 (show CYP2C19 Antibodies)*2 are possible predictors of CVE in patients after CABG
Studied the association between integrin subunit alpha 2 (GPIa) and prostaglandin-endoperoxide synthase 2 (COX-2 (show PTGS2 Antibodies)) genetic polymorphisms in Chinese ishemic stroke patients with or without aspirin resistance.
The authors identified a cell surface marker, ITGA2, which marks a proliferative trophoblast progenitor compartment in the first trimester placenta that is regulated by NOTCH (show NOTCH1 Antibodies) signalling and exhibits unique expression characteristics.
discovered that OLFM4 (show OLFM4 Antibodies), CD11b (show ITGAM Antibodies), and ITGA2 are proteins that are overexpressed in both primary colon tumors and liver metastasis. These are colon cancer biomarkers with autoantigenic properties.
This study demonstrated that the transactivation of FOXL2 (show FOXL2 Antibodies) driven by interactions between HMGA2 and pRb (show RB1 Antibodies) might exert critical effects on the metastases and EMT (show ITK Antibodies) of chemoresistant gastric cancer. Blocking the HMGA2-FOXL2 (show FOXL2 Antibodies)-ITGA2 pathway could serve as a new strategy for gastric cancer treatment.
The GpIa-C807T and GpIIIa (show ITGB3 Antibodies)-PlA1 (show POU2F3 Antibodies)/PlA2 (show YWHAZ Antibodies) polymorphisms and more pronouncedly their combination are associated with increased risk of spontaneous abortions.
The allele combination of CGC from hOGG1, ITGA2 and XPD (show ERCC2 Antibodies) polymorphisms was significantly associated with increased odds of nasopharyngeal carcinoma.
blood platelets have a role in amyloid-beta aggregation in cerebral vessels through integrin alphaIIbbeta3-induced outside-in signaling and clusterin (show CLU Antibodies) release
Exposure to magnesium ions facilitated hBMSC proliferation via integrin alpha2 and alpha3 expression and partly promoted differentiation into osteoblasts via the alteration of ALP (show ALP Antibodies) expression and activity
The synonymous common variant, GPIA rs1126643, increases the long-term adverse events risk of CABG by augmenting GPIa protein expression and enhancing platelet aggregation function.

Mouse (Murine) Integrin alpha 2 (ITGA2) interaction partners

Study in a mouse model of collagen-induced arthritis identified the integrin alpha2 gene (Itga2) as an additional and novel biomarker for rheumatoid arthritis.
P15 (show CDKN2B Antibodies) does not directly activate integrins by binding, but does upregulate integrin signaling to enhance differentiation of both osteoblasts and chondrocytes to increase both intramembranous and endochondral bone formation.
low expression of alpha2beta1 integrin increased protein kinase B (AKT) activation and alpha-smooth muscle actin (alpha-SMA) expression. This occurred due to the instability of phosphatase and tensin homolog (PTEN) in myofibroblasts on fibrillar collagen.
Ceacam1 (show CEACAM1 Antibodies) is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 (show CEACAM1 Antibodies) induced moderate integrin aIIbb3-mediated functional defects.
HRG (show HRG Antibodies) binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.
LG3, through interactions with alpha2beta1 integrins on recipient-derived cells leading to activation of ERK1/2 and increased migration, favors myointimal thickening
IFN-gamma (show IFNG Antibodies) induces aberrant CD49b+ NK cell recruitment and pregnancy failure through regulating CX3CL1 (show CX3CL1 Antibodies).
alphaIIbbeta3 regulates Syk (show SYK Antibodies) through an ITAM-independent pathway in mice and provide novel insight into the course of events underlying Syk (show SYK Antibodies) activation and hemITAM phosphorylation by CLEC-2 (show CLEC1B Antibodies)
the collagen receptors DDR1 (show DDR1 show) and integrin a2b1 contribute to regulate GBM-maturation and to control matrix accumulation.
alpha2beta1 integrin contributes to the pathogenesis of retinopathy. We describe a newly identified role for alpha2beta1 integrin in mediating hypoxia-induced Muller cell VEGF-A (show VEGFA Antibodies) production.

Cow (Bovine) Integrin alpha 2 (ITGA2) interaction partners

Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
both the gpIb-VWF (show VWF Antibodies) interaction and the integrin alpha(2)beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Antibodies))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF Antibodies) is bound

Integrin alpha 2 (ITGA2) Antigen Profile

Antigen Summary

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Integrin alpha 2 (ITGA2)

integrin subunit alpha 2 (ITGA2) antibody
integrin alpha 2 (Itga2) antibody
integrin subunit alpha 2 (Itga2) antibody

BR antibody
CD49B antibody
DX5 antibody
GPIa antibody
HPA-5 antibody
VLA-2 antibody
VLAA2 antibody

Protein level used designations for ITGA2

CD49 antigen-like family member B , VLA2 receptor, alpha-2 subunit , collagen receptor , human platelet alloantigen system 5 , integrin alpha-2 , platelet antigen Br , platelet glycoprotein GPIa , platelet membrane glycoprotein Ia , very late activation protein 2 receptor, alpha-2 subunit , GPIa , VLA-2 receptor, alpha 2 subunit , VLA-2 subunit alpha , VLA-2 alpha chain , LOW QUALITY PROTEIN: integrin alpha-2 , integrin alpha 2 subunit , integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

GENE ID	SPECIES
3673	Homo sapiens
16398	Mus musculus
170921	Rattus norvegicus
281872	Bos taurus
100729266	Cavia porcellus
397483	Sus scrofa

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Show all anti-Integrin alpha 2 (ITGA2) Antibodies with Pubmed References