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Compares and contrasts all the known human SLC25A (show SLC25A25 Proteins)* genes and includes functional information.
OGC as a model protein for understanding the transport mechanism of mitochondrial carriers.
OGCP degrades through proteasome and lysosome degradation pathways. The degradation of parkin protein can promote the degradation of OGCP.
Controlling MISC-1/OGC function allows regulation of mitochondrial morphology and cell survival decisions by the metabolic needs of the cell.
data provide evidence for a role of the 2-oxoglutarate carrier as a glutathione transporting polypeptide
porphyrin accumulation in mitochondria is mediated by OGC and porphyrins are able to competitively inhibit 2-oxoglutarate uptake into mitochondria
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992
putative oxoglutarate/malate carrier
, mitochondrial 2-oxoglutarate/malate carrier protein
, solute carrier family 25 member 11
, solute carrier family 20 (oxoglutarate carrier), member 4
, 2-oxoglutarate carrier