Browse our LMO1 Proteins (LMO1)

Full name:: LIM Domain Only 1 (Rhombotin 1) Proteins (LMO1)

On www.antibodies-online.com are 13 LIM Domain Only 1 (Rhombotin 1) (LMO1) Proteins from 5 different suppliers available. Additionally we are shipping LMO1 Antibodies (38) and and many more products for this protein. A total of 57 LMO1 products are currently listed.

Synonyms:: cb524, Dat1, LMO1, Lmo3, Rbtn-1, RBTN1, RHOM1, TTG1, wu:fb76g02, zgc:109794

list all proteins	Gene Name	GeneID	UniProt
	LMO1	109594	Q924W9
Rat LMO1	LMO1	245979
	LMO1	4004	P25800
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Relevant Pathways for LMO1 Proteins

Dopaminergic Neurogenesis

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Mouse (Murine) LIM Domain Only 1 (Rhombotin 1) (LMO1) interaction partners

SCL (show TAL1 Proteins)-LMO1 upregulated a stem cell gene signature in DN3 thymocytes.
Loss of Lmo1 repression may be one of the causes accounting for the phenotypic differences identified between the Arx((GCG)7)and Arx(432-455dup24) mouse models.
SCL (show TAL1 Proteins), LMO1, and Notch1 (show NOTCH1 Proteins) gain of function, together with an active pre-T-cell antigen receptor (show PTCRA Proteins), might represent the minimum set of complementing events for the transformation of susceptible thymocytes into cancer cells
Results suggest that all four members of the LIM (show PDLIM5 Proteins)-only family -- LMO1, 2, 3, and 4 -- are important regulators of distinct developmental pathways.
Lmo1 takes part in a Hox (show MSH2 Proteins) paralogue 2-dependent network regulating anteroposterior and dorsoventral hindbrain patterning

Human LIM Domain Only 1 (Rhombotin 1) (LMO1) interaction partners

IKZF1 (show IKZF1 Proteins) rs10235796 C allele, IKZF1 (show IKZF1 Proteins) rs6964969A>G, CDKN2A rs3731246 G>C, and CDKN2A rs3731246 C allele were signi fi cantly associated with Acute Lymphoblastic Leukemia in Yemenis of Arab-Asian descent. Borderline association found in IKZF1 (show IKZF1 Proteins) rs4132601 T>G variant. No associations found with LMO1 rs442264; rs3794012; rs4237770
These results suggested that LMO1 gene rs110419 A > G polymorphism may contribute to protection against neuroblastoma (show ARHGEF16 Proteins)
A C-to-T single nucleotide transition occurs as a somatic mutation in noncoding sequences 4 kb upstream of the transcriptional start site of the LMO1 oncogene (show RAB1A Proteins) in primary samples from patients with T-cell acute lymphoblastic leukaemia. This conforms to an APOBEC-like cytidine deaminase (show CDA Proteins) mutational signature and a new MYB (show MYB Proteins) binding site driving high levels of LMO1 expression.
LMO1 is an important oncogene (show RAB1A Proteins) that promotes neuroblastoma (show ARHGEF16 Proteins) initiation, progression, and widespread metastatic dissemination.
LMO1 appears to be a coactivator of AR involved in the progression of prostate cancer
data suggest that genetic variants in LMO1 are associated with increased NB risk in Chinese children.
a polymorphism within a super-enhancer element in the first intron of LMO1 influences neuroblastoma (show ARHGEF16 Proteins) susceptibility through differential GATA (show QRSL1 Proteins) transcription factor binding and direct modulation of LMO1 expression in cis (show CISH Proteins)
LMO1 is a commonly activated tumor promoter that activates AKT (show AKT1 Proteins) signaling in non-small cell lung cancer.
LMO1 is a commonly activated tumor promoter that activates AKT (show AKT1 Proteins) signaling in colorectal cancer and a new predictive marker for targeted therapy.
results show that LMO1 is poised for expression in normal progenitors, where activation of SCL/TAL1 (show TAL1 Proteins) together with a breakdown of epigenetic repression of LMO1 regulatory elements

LMO1 Protein Profile

Protein Summary

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions\; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with LMO1

LIM domain only 1 (LMO1)
Rhombotin-1 (rbtn1)
LIM domain only 1 (Lmo1)
LIM domain only 1 (lmo1)

cb524 protein
Dat1 protein
LMO1 protein
Lmo3 protein
Rbtn-1 protein
RBTN1 protein
RHOM1 protein
TTG1 protein
wu:fb76g02 protein
zgc:109794 protein

Protein level used designations for LMO1

LIM domain only 1 (rhombotin 1) , Rhombotin-1 , LIM domain only protein 1 , LIM only 1 , LMO-1 , T-cell translocation protein 1 , cysteine-rich protein TTG-1 , rhombotin-1 , etID41074.7 , lmo1b , LIM domain only protein 3 , LMO-3 , LIM domain only 3 , neuronal-specific transcription factor DAT1 , dopamine-inducible LIM-domain transcription factor DAT1 , T-cell translocation gene 1 , rhombotin 1

GENE ID	SPECIES
749084	Pan troglodytes
100286459	Salmo salar
109594	Mus musculus
280646	Danio rerio
245979	Rattus norvegicus
4004	Homo sapiens
527152	Bos taurus
734798	Xenopus laevis

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