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LOX Proteins

(Lysyl Oxidase (LOX))
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].

Active filters:

  • Target: LOX
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7123817
LOX Protein (AA 174-417) (His-IF2DI Tag) LOX · Protein Human Escherichia coli (E. coli)
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$510.30 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN2712316
LOX Protein (Myc-DYKDDDDK Tag) LOX · Protein Human HEK-293 Cells
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
$1,112.40 View price
  • 20 μg
Delivery in 11 to 12 Business Days Shipping to: United States
ABIN7856610
LOX Protein (GST tag) LOX · Protein Human Baculovirus infected Insect Cells
  • WB (Western Blotting: Listed application)
$779.38 View price
  • 100 μg
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN2130388
LOX Protein LOX · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
$823.89 View price
  • 100 μg
Delivery in 9 to 12 Business Days Shipping to: United States
ABIN7396547
LOX Protein (AA 213-417) (His tag,GST tag) LOX · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$721.75 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7396550
LOX Protein (AA 207-411) (His tag,GST tag) LOX · Protein Mouse Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$753.80 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7424992
LOX Protein (AA 169-417) (His tag) LOX · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$737.78 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128683
LOX Protein (AA 169-417) (His tag) LOX · Protein Human HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$601.57 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128684
LOX Protein (AA 213-417) LOX · Protein Human Escherichia coli (E. coli)
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$801.88 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7584987
LOX Protein (AA 163-411) (His tag) LOX · Protein Rat Yeast
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Listed application)
$1,280.97 View price
  • 100 μg
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN3010561
LOX Protein (His tag,GST tag) LOX · Protein Mouse Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Validation image available)
  • WB (Western Blotting: Listed application)
$826.86 View price
  • 100 μg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN2725073
LOX Protein (DYKDDDDK-His Tag) LOX · Protein Human HEK-293 Cells
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
$1,152.00 View price
  • 20 μg
Delivery in 11 to 12 Business Days Shipping to: United States
ABIN6239913
LOX Protein (AA 213-417) (His tag,GST tag) LOX · Protein Human Escherichia coli (E. coli)
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$720.00 View price
  • 50 μg
  • 1 mg
Delivery in 15 to 19 Business Days Shipping to: United States
ABIN1458763
LOX Protein (AA 172-420) (His tag) LOX · Protein Chicken Yeast
  • ELISA (ELISA: Listed application)
$2,822.84 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1472498
LOX Protein (AA 1-249) (His tag) LOX · Protein Pig Yeast
  • ELISA (ELISA: Listed application)
$2,822.84 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7584986
LOX Protein (AA 170-418) (His tag) LOX · Protein Cow Yeast
  • ELISA (ELISA: Listed application)
$1,280.97 View price
  • 100 μg
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7963466
LOX Protein (His-SUMO Tag,MYC tag) LOX · Protein Human Escherichia coli (E. coli)
$488.40 View price
  • 100 μg
  • 1 mg
  • 20 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7964252
LOX Protein (MBP tag,His tag) LOX · Protein Human Baculovirus infected Insect Cells
$1,112.10 View price
  • 100 μg
  • 1 mg
  • 20 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7817289
LOX Protein (AA 169-417) (His tag) LOX · Protein Human Bacteria
$500.50 View price
  • 100 μg
Delivery in 7 to 10 Business Days Shipping to: United States
ABIN7942525
LOX Protein (His tag) LOX · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
$478.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
Protein
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7123817
$510.30
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2712316
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Baculovirus infected Insect Cells
Protein Type
Recombinant
Catalog No. ABIN7856610
$779.38
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 85 % pure
Catalog No. ABIN2130388
$823.89
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 9 to 12 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7396547
$721.75
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7396550
$753.80
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7424992
$737.78
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Human
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN8128683
$601.57
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Biological Activity
Active
Catalog No. ABIN8128684
$801.88
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Rat
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7584987
$1,280.97
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • WB (Western Blotting: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN3010561
$826.86
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2725073
$1,152.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Biological Activity
Active
Catalog No. ABIN6239913
$720.00
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Chicken
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1458763
$2,822.84
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Pig
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1472498
$2,822.84
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Cow
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7584986
$1,280.97
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 85 % as determined by SDS-PAGE.
Catalog No. ABIN7963466
$488.40
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Human
Host
Baculovirus infected Insect Cells
Protein Type
Recombinant
Purity
Greater than 85 % as determined by SDS-PAGE.
Catalog No. ABIN7964252
$1,112.10
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Human
Host
Bacteria
Protein Type
Recombinant
Catalog No. ABIN7817289
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 10 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7942525
$478.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days

Latest Publications for our LOX Proteins

Pilecki, Holm, Schlosser, Moeller, Wohl, Zuk, Heumüller, Wallis, Moestrup, Sengle, Holmskov, Sorensen: "Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation." in: The Journal of biological chemistry, Vol. 291, Issue 3, pp. 1103-14, (2016) (PubMed).

Kondala, Puri, Banka, Sachdeva, Sakhuja: "Short-term prognosis of potential celiac disease in Indian patients." in: United European gastroenterology journal, Vol. 4, Issue 2, pp. 275-80, (2016) (PubMed).

Tsukasaki, Hamada, Okamoto, Nagashima, Terashima, Komatsu, Win, Okamura, Nitta, Yasuda, Penninger, Takayanagi: "LOX Fails to Substitute for RANKL in Osteoclastogenesis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 32, Issue 3, pp. 434-439, (2016) (PubMed).

Cox, Rumney, Schoof, Perryman, Høye, Agrawal, Bird, Latif, Forrest, Evans, Huggins, Lang, Linding, Gartland, Erler: "The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase." in: Nature, Vol. 522, Issue 7554, pp. 106-10, (2015) (PubMed).

Miller, Morton, Pinese, Saturno, Jamieson, McGhee, Timpson, Leach, McGarry, Shanks, Bailey, Chang, Oien, Karim, Au, Steele, Carter, McKay, Anderson, Evans, Marais, Springer, Biankin, Erler, Sansom: "Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy." in: EMBO molecular medicine, Vol. 7, Issue 8, pp. 1063-76, (2015) (PubMed).

Richter, Dayaram, Gilmartin, Ganji, Pemmasani, Van Der Key, Shohet, Donehower, Kumar: "WIP1 phosphatase as a potential therapeutic target in neuroblastoma." in: PLoS ONE, Vol. 10, Issue 2, pp. e0115635, (2015) (PubMed).

Zhao, Sagare, Ma, Halliday, Kong, Kisler, Winkler, Ramanathan, Kanekiyo, Bu, Owens, Rege, Si, Ahuja, Zhu, Miller, Schneider, Maeda, Maeda, Sugawara, Ichida, Zlokovic: "Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance." in: Nature neuroscience, Vol. 18, Issue 7, pp. 978-87, (2015) (PubMed).

Arnold, Kent, Hogarth, Schlatt, Prasad, Haenisch, Walsh, Muller, Griswold, Amory, Isoherranen: "Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations." in: Journal of lipid research, Vol. 56, Issue 2, pp. 342-57, (2015) (PubMed).

Wilson, Bradley, Shaw, Wagenmakers: "Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature." in: Histochemistry and cell biology, Vol. 142, Issue 3, pp. 245-56, (2014) (PubMed).

Nandhu, Hu, Cole, Erdreich-Epstein, Rodriguez-Gil, Viapiano: "Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas." in: Cancer research, Vol. 74, Issue 19, pp. 5435-48, (2014) (PubMed).

Aliases for LOX Proteins

lysyl oxidase (LOX) Proteins
lysyl oxidase (lox) Proteins
lysyl oxidase a (loxa) Proteins
lysyl oxidase L homeolog (lox.L) Proteins
lysyl oxidase (Lox) Proteins
AI893619 Proteins
H-rev142 Proteins
LOX Proteins
lox Proteins
MGC146507 Proteins
Rrg1 Proteins
TSC-160 Proteins
Xlox Proteins
zgc:77447 Proteins
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