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Browse our DNAJB9 Proteins (DNAJB9)

Full name:: Microvascular Endothelial Differentiation Gene 1 Protein Proteins (DNAJB9)

On www.antibodies-online.com are 6 Microvascular Endothelial Differentiation Gene 1 Protein (DNAJB9) Proteins from 4 different suppliers available. Additionally we are shipping DNAJB9 Antibodies (67) and and many more products for this protein. A total of 80 DNAJB9 products are currently listed.

Synonyms:: AA408011, AA673251, AA673481, AW556981, ERdj4, MDG-1, Mdg1, mDj7, MST049, MSTP049

list all proteins	Gene Name	GeneID	UniProt
	DNAJB9	4189	Q9UBS3
	DNAJB9	27362	Q9QYI6
	DNAJB9	24908	P97554
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Relevant Pathways for DNAJB9 Proteins

ER-Nucleus Signaling

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Human Microvascular Endothelial Differentiation Gene 1 Protein (DNAJB9) interaction partners

Study reports that the endoplasmic reticulum luminal co-chaperone ERdj4/DNAJB9 is a selective IRE1 repressor that promotes a complex between the luminal Hsp70 BiP and the luminal stress-sensing domain of IRE1alpha.
these results demonstrate that DNAJB9 is a downstream target of p53 that belongs to the group of negative feedback regulators of p53.
ERdj4 and ERdj5 promote turnover of misfolded SP-C and this activity is dependent on their ability to stimulate BiP ATPase activity.

Mouse (Murine) Microvascular Endothelial Differentiation Gene 1 Protein (DNAJB9) interaction partners

ERdj4 gene trap mice showed non-specific hypergammaglobulinemia and gene trap B cells exhibited increased proliferation, survival and isotype switching in response to LPS stimulation.
these results demonstrate that DNAJB9 is a downstream target of p53 that belongs to the group of negative feedback regulators of p53.
Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects.
directly link ERdj4 to the ERAD machinery and suggest a model in which ERjd4 could help recruit clients from throughout the ER to ERAD sites
DnaJ homolog, which stimulates ATPase activity of BiP and is induced by endoplasmic reticulum stress

DNAJB9 Protein Profile

Protein Summary

This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis.

Alternative names and synonyms associated with DNAJB9

DnaJ heat shock protein family (Hsp40) member B9 (DNAJB9)
DnaJ heat shock protein family (Hsp40) member B9 (Dnajb9)

AA408011 protein
AA673251 protein
AA673481 protein
AW556981 protein
ERdj4 protein
MDG-1 protein
Mdg1 protein
mDj7 protein
MST049 protein
MSTP049 protein

Protein level used designations for DNAJB9

dnaJ homolog subfamily B member 9 , endoplasmic reticulum DnaJ homolog 4 , microvascular endothelial differentiation gene 1 protein , DNA j protein b9 , microvascular endothelial differentiation gene 1 , dnaJ homolog, subfamily b, member 9 , mdg-1

GENE ID	SPECIES
614588	Bos taurus
4189	Homo sapiens
27362	Mus musculus
24908	Rattus norvegicus
475286	Canis lupus familiaris

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