HYOU1 ELISA Kits

Protein Summary

The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal.

Alternative names and synonyms associated with HYOU1

• hypoxia up-regulated 1 (HYOU1) antibody
• hypoxia up-regulated 1 (Hyou1) antibody
• hypoxia up-regulated 1 (hyou1) antibody
• hypoxia up-regulated protein 1 (LOC100380749) antibody
• hypoxia up-regulated 1 S homeolog (hyou1.S) antibody

• AI415631 antibody
• Cab140 antibody
• CBP-140 antibody
• GRP-170 antibody
• GRP170 antibody
• Show all synonym aliases
• HSP12A antibody
• HYOU1 antibody
• id:ibd5056 antibody
• ORP-150 antibody
• orp150 antibody
• wu:fd14c05 antibody
• zgc:56019 antibody

Protein level used designations for HYOU1

150 kDa oxygen-regulated protein , 170 kDa glucose-regulated protein , glucose-regulated protein 170 , hypoxia up-regulated protein 1 , oxygen regulated protein (150kD) , 140 kDa Ca(2+)-binding protein , 150-kDa oxygen regulated protein , 170 kDa glucose regulated protein GRP170 , GRP-170 , calcium binding protein 140 , calcium binding protein, 140 kDa , ORP-150 , hypoxia up-regulated 1 , Hypoxia up-regulated protein 1 , hypoxia up-regulated protein 1-like , glucose regulated protein, 170 kDa , oxygen regulated protein, 150 kDa