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ERBB3 Antibodies

(Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
ERBB3 antibody  (AA 707-964) ERBB3 antibody  (AA 707-964) ERBB3 antibody (AA 707-964) (ABIN7440773)

ERBB3 Reactivity: Mouse ICC, IHC, IP, WB Host: Rabbit Polyclonal unconjugated

ERBB3 antibody  (N-Term) ERBB3 antibody  (N-Term) ERBB3 antibody (N-Term) (ABIN391949)

ERBB3 Reactivity: Human, Mouse FACS, IHC (p), WB Host: Rabbit Polyclonal RB01467 unconjugated

ERBB3 antibody  (AA 24-55) ERBB3 antibody  (AA 24-55) ERBB3 antibody (AA 24-55) (ABIN3029524)

ERBB3 Reactivity: Human, Mouse FACS, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

ERBB3 Antibodies by Grade

Find ERBB3 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Reactivity

Find ERBB3 Antibodies for a variety of species such as anti-Human ERBB3, anti-Rat ERBB3, anti-Mouse ERBB3. The species listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Application

Find ERBB3 Antibodies validated for a specific application such as WB, ELISA, IF (p), IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Host

Find ERBB3 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Binding Specificity

Find ERBB3 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Clonality

Find available monoclonal or polyclonal ERBB3 Antibodies. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Clone

Find ERBB3 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

ERBB3 Antibodies by Conjugate

Find ERBB3 Antibodies with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ERBB3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application ICC, IHC, IP, WB
Validations
  • (6)
Cat. No. ABIN7440773
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IHC (p), WB
Validations
  • (4)
  • (5)
Cat. No. ABIN391949
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3029524
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, FACS, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN681358
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (4)
Cat. No. ABIN747113
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN6261585
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), ELISA, WB
Validations
  • (4)
Cat. No. ABIN560779
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7008552
Quantity 60 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (2)
  • (2)
Cat. No. ABIN686767
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (3)
Cat. No. ABIN800628
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7138931
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application DB, WB
Validations
  • (5)
  • (2)
Cat. No. ABIN1881314
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ICC, ELISA, WB
Validations
  • (2)
  • (2)
Cat. No. ABIN969114
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (2)
  • (2)
Cat. No. ABIN969112
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IF, IHC
Validations
  • (3)
Cat. No. ABIN185461
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ERBB3 Antibodies

Memon, Gilliver, Borre, Sundquist, Sundquist, Nexo, Sorensen: "Soluble HER3 predicts survival in bladder cancer patients." in: Oncology letters, Vol. 15, Issue 2, pp. 1783-1788, (2018) (PubMed).

Cao, Chen, Chen, Xiong: "Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients." in: BMC cancer, Vol. 17, Issue 1, pp. 841, (2018) (PubMed).

Zomerman, Plasschaert, Diks, Lourens, Meeuwsen-de Boer, Hoving, den Dunnen, de Bont: "Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141381, (2015) (PubMed).

Liu, Leng, Gunasekaran, Pentony, Shen, Howard, Stoops, Manchulenko, Razinkov, Liu, Fanslow, Hu, Sun, Hasegawa, Clark, Foltz, Yan: "A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism." in: The Journal of biological chemistry, (2015) (PubMed).

Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: "Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122555, (2015) (PubMed).

Cheng, Terai, Kageyama, Ozaki, McCue, Sato, Aplin: "Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma." in: Cancer research, Vol. 75, Issue 13, pp. 2737-48, (2015) (PubMed).

Davies, Holmes, Lomo, Steinkamp, Kang, Muller, Wilson: "High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 33, Issue 4, pp. 402-10, (2014) (PubMed).

Mimura, Shiraishi, Mueller, Izawa, Kua, So, Yong, Fujii, Seliger, Kiessling, Kono: "The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 12, pp. 6261-72, (2013) (PubMed).

Lee, Chin, Li: "Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking." in: The Journal of cell biology, Vol. 199, Issue 5, pp. 799-816, (2012) (PubMed).

MacLeod, Elgadi, Bossi, Sankar, Pisio, Agopsowicz, Sharon, Graham, Hitt: "HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice." in: Cancer gene therapy, Vol. 19, Issue 12, pp. 888-98, (2012) (PubMed).

Aliases for ERBB3 Antibodies

erb-b2 receptor tyrosine kinase 3 (ERBB3) Antibodies
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) Antibodies
erb-b2 receptor tyrosine kinase 3 (Erbb3) Antibodies
c-erbB-3 Antibodies
c-erbB3 Antibodies
C76256 Antibodies
ErbB-3 Antibodies
Erbb-3 Antibodies
ERBB3 Antibodies
erbB3-S Antibodies
Erbb3r Antibodies
HER3 Antibodies
Her3 Antibodies
LCCS2 Antibodies
MDA-BF-1 Antibodies
nuc-ErbB3 Antibodies
p45-sErbB3 Antibodies
p85-sErbB3 Antibodies
p180-ErbB3 Antibodies
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