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anti-Human HCLS1 Antibodies:
anti-Mouse (Murine) HCLS1 Antibodies:
anti-Rat (Rattus) HCLS1 Antibodies:
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Human Monoclonal HCLS1 Primary Antibody for IF, IP - ABIN968027
Fukuda, Kitamura, Taniuchi, Maekawa, Benhamou, Sarthou, Watanabe: Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate. in Proceedings of the National Academy of Sciences of the United States of America 1995
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Human Monoclonal HCLS1 Primary Antibody for IF, ELISA - ABIN561238
Kan, Wen, Pasquier, Jankowski, Chang, Richards, Kavallaris, MacKenzie: Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization. in Oncogene 2012
Cow (Bovine) Polyclonal HCLS1 Primary Antibody for IHC, WB - ABIN2777503
Ruzzene, Penzo, Pinna: Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. in The Biochemical journal 2002
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Human Monoclonal HCLS1 Primary Antibody for IF, IP - ABIN968026
Takemoto, Furuta, Li, Strong-Sparks, Hashimoto: LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck. in The EMBO journal 1995
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Cow (Bovine) Polyclonal HCLS1 Primary Antibody for IHC, WB - ABIN2777502
Barcroft: The Oxygen Tension in the Submaxillary Glands and certain other tissues. in The Biochemical journal 2006
Show all 2 Pubmed References
these studies indicate HS1 (show EEF1A2 Antibodies) plays an important role in ROR1 (show ROR1 Antibodies)-dependent Wnt5a (show WNT5A Antibodies)-enhanced chemokine (show CCL1 Antibodies)-directed leukemia-cell migration.
SDF1alpha-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells.
Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 (show PAK1 Antibodies) and Ezrin (show EZR Antibodies) in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 (show FLT3 Antibodies) receptors.
interaction of HCLS1 with LEF-1 (show LEF1 Antibodies) is essential for G-CSF (show CSF3 Antibodies)-triggered myeloid differentiation; data demonstrate the importance of HCLS1 in myelopoiesis in vitro and in vivo
HS1 (show EEF1A2 Antibodies) overexpressed in leukemic as compared to normal B lymphocytes.
a novel role for HS1 (show EEF1A2 Antibodies) and its phosphorylation during neutrophil directed migration.
High HS1 (show EEF1A2 Antibodies) expression predicts poor survival of chronic lymphocytic leukemia patients.
SH3 domain (show ITSN1 Antibodies) of HS1 (show EEF1A2 Antibodies) protein recognizes lysine-rich polyproline motifs.
HS1 is a central regulator of (show RAG2 Antibodies) cytoskeleton remodeling that controls ly (show EEF1A2 Antibodies)mphocyte trafficking and homing and significantly influences the tissue invasion and infiltration in chronic lymphocytic leukemia.
substrate for caspase (show CASP3 Antibodies) cleavage during apoptosis
HS1 as an important regulator of proper Rac1 and Rap1 activation and neutrophil extravasation.
Results identified two proteins P23 (show CDK5R1 Antibodies) and HCLS1, which were not known as RNA-binding proteins, exhibiting RNA-binding activity.
studies show that HS1 promotes an early step in the endocytic pathway that is required for efficient Ag presentation of exogenous Ag by dendritic cells
Studies show that HS1 functions in concert with WASp to fine-tune DC cytoarchitecture and direct cell migration.
In vivo, immunodeficient Rag2 (show RAG2 Antibodies)(-/-)gamma(c)(-/-) mice injected with HS1-silenced CLL B cells showed a decreased organ infiltration with the notable exception of the bone marrow.
Hematopoietic lineage cell specific protein 1 (show SP1 Antibodies) plays a significant functional role in platelet activation downstream of glycoprotein VI and protease-activated receptors[Hematopoietic lineage cell specific protein 1 (show SP1 Antibodies)]
data indicate that Syk (show SYK Antibodies) kinase plays an important role in the translocation of hematopoietic lineage cell-specific protein 1 (show SP1 Antibodies) (HS1) into lipid rafts
This study concludes that HS1 does not play a major role in platelet function. It is possible that a role for HS1 is masked by the presence of cortactin (show CTTN Antibodies).
tyrosine phosphorylation of HS1 occurs downstream of both PAR-1 (show MARK2 Antibodies) and PAR-4 (show F2RL3 Antibodies). HS1 phosphorylation is a Gq mediated response regulated by Src (show SRC Antibodies) kinases
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
hematopoietic lineage cell-specific protein
, hematopoietic cell-specific LYN substrate 1
, hematopoietic cell-specific Lyn substrate 1
, hematopoietic lineage cell-specific protein-like
, Hematopoietic lineage cell-specific protein
, uncharacterized protein LOC563056