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Brain-specific-homeobox (Bsh) protein, which is expressed in the lamina and medulla ganglia, is involved in specifying neuronal identity.
Agouti related peptide is a common orexigenic target gene of glucocorticoid receptor and Bsx in the mouse hypothalamus.
Bsx and TTF-1 are transcriptional factors of NPY and AgRP in the arcuate nucleus[review]
binding of REST to neuron restrictive silencer element suppresses transcriptional activator Sp1-mediated activation of bsx in non-neuronal cells
Might be considered an important molecular marker for early embryonic stages of epiphysis development.
Data demonstrate that BSX1A is a DNA binding protein and a transcriptional activator, and that BSX1A and BSX1B localize in the nuclei and cytoplasm, respectively.
These results demonstrate that Bsx is required for postnatal growth and maintenance of lactating mammary glands.
Bsx has a pivotal role in the differentiation of multiple cell types in the zebrafish pineal complex.
Data suggest that BSX is essential for global cognitive function and that haplo-insufficiency may cause severe mental retardation, and that deletion of Neurogranin
DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain.
, brain specific homeobox
, brain-specific homeobox
, brain-specific homeobox protein homolog
, brain-specific homeodomain protein