anti-ABCC5 Antibodies

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear.

Alternative names and synonyms associated with ABCC5

• ATP binding cassette subfamily C member 5 (ABCC5) antibody
• ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5) antibody
• ATP binding cassette subfamily C member 5 (Abcc5) antibody
• ATP binding cassette subfamily C member 5 L homeolog (abcc5.L) antibody

• 2900011L11Rik antibody
• abc33 antibody
• abcc5 antibody
• Abcc5a antibody
• Abcc5b antibody
• Show all synonym aliases
• AI132311 antibody
• EST277145 antibody
• moat-c antibody
• moatc antibody
• mrp5 antibody
• pabc11 antibody
• smrp antibody

Protein level used designations for ABCC5

ATP-binding cassette sub-family C member 5 , canalicular multispecific organic anion transporter C , multi-specific organic anion transporter C , multidrug resistance-associated protein 5 , ATP-binding cassette, sub-family C (CFTR/MRP), member 5a , ATP-binding cassette, sub-family C (CFTR/MRP), member 5b , ATP-binding cassette, sub-family C, member 5 , MOAT-C , SMRP , ATP-binding cassette sub-family C (CFTR/MRP) member 5a , ATP-binding cassette, sub-family C (CFTR/MRP), member 5 , ATP binding cassette subfamily C member 5 L homeolog