Hemagglutinin Esterase Protein (HE) (AA 19-424) (His tag)
This Recombinant Hemagglutinin Esterase protein is produced in Yeast.
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Catalog No. ABIN5714060
Quick Overview for Hemagglutinin Esterase Protein (HE) (AA 19-424) (His tag) (ABIN5714060)
Target
Hemagglutinin Esterase (HE)
Protein Type
Recombinant
Origin
Bovine Coronavirus (BCoV)
Source
Yeast
Application
SDS-PAGE (SDS)
Purity
> 90 %
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Protein Characteristics
- AA 19-424
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Purification tag / Conjugate
- This Hemagglutinin Esterase protein is labelled with His tag.
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Sequence
- FDNPPTNVVS HLNGDWFLFG DSRSDCNHVV NTNPRNYSYM DLNPALCDSG KISSKAGNSI FRSFHFTDFY NYTGEGQQII FYEGVNFTPY HAFKCTTSGS NDIWMQNKGL FYTQVYKNMA VYRSLTFVNV PYVYNGSAQS TALCKSGSLV LNNPAYIARE ANFGDYYYKV EADFYLSGCD EYIVPLCIFN GKFLSNTKYY DDSQYYFNKD TGVIYGLNST ETITTGFDFN CHYLVLPSGN YLAISNELLL TVPTKAICLN KRKDFTPVQV VDSRWNNARQ SDNMTAVACQ PPYCYFRNST TNYVGVYDIN HGDAGFTSIL SGLLYDSPCF SQQGVFRYDN VSSVWPLYSY GRCPTAADIN TPDVPICVYD PLPLILLGIL LGVAVIIIVV LLLYFMVDNG TRLHDA
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Purification
- SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Hemagglutinin Esterase (HE)
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Alternative Name
- Hemagglutinin Esterase
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Target Type
- Viral Protein
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Background
- Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. Ses to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune syst.
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Molecular Weight
- 47.7 kDa
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UniProt
- P15776
Target
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