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anti-Mouse (Murine) IFT74 Antibodies:
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Human Polyclonal IFT74 Primary Antibody for ICC, IF - ABIN268555
Bell, Mavila, Salazar, Bayless, Kanagala, Maxwell, Davis et al.: Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular ... in Journal of cell science 2001
Show all 2 Pubmed References
Human Polyclonal IFT74 Primary Antibody for ELISA, IF - ABIN185213
Momeni, Schymick, Jain, Cookson, Cairns, Greggio, Greenway, Berger, Pickering-Brown, Chiò, Fung, Holtzman, Huey, Wassermann, Adamson, Hutton, Rogaeva, St George-Hyslop, Rothstein, Hardiman, Grafman et al.: Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. ... in BMC neurology 2007
Show all 3 Pubmed References
Human Polyclonal IFT74 Primary Antibody for EIA, IHC (p) - ABIN372546
Boldt, Mans, Won, van Reeuwijk, Vogt, Kinkl, Letteboer, Hicks, Hurd, Naggert, Texier, den Hollander, Koenekoop, Bennett, Cremers, Gloeckner, Nishina, Roepman, Ueffing: Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice. in The Journal of clinical investigation 2011
These results indicate that, together, the IFT81 and IFT74 N-termini are crucial for flagellar assembly, and are likely to function as the main module for IFT of tubulin.
conclude that IFT74 is required to stabilize IFT-B; aa 197-641 are sufficient for this function in vivo
The CMG-1 serves as a transcriptional regulator of proliferation and adhesion-associated genes in early stage male germ-line cells in the testis.
Results identify a cDNA encoding the mouse ortholog of capillary morphogenesis gene (CMG)-1, and suggest that CMG-1 may play a role in the transcriptional regulation of the cyclin D2 gene.
Ift74 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
this study found that the two core intraflagellar transport proteins IFT74 and IFT81 form a tubulin-binding module and mapped the interaction to a calponin homology domain of IFT81 and a highly basic domain in IFT74.
The results revealed that the common variations in IFT74 and GRN neither constitute strong ALS risk factors nor modify the age-at-onset.
putative nuclear transcription factor; member of the TIS11 family of early response genes; may regulate the response to growth factors
intraflagellar transport protein 74/72
, intraflagellar transport protein 74 homolog
, intraflagellar transport 74 homolog (Chlamydomonas)
, coiled-coil domain containing 2
, capillary morphogenesis gene 1 protein
, capillary morphogenesis protein 1
, coiled-coil domain-containing protein 2
, intraflagellar transport 74 homolog