anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta Antibodies

Protein Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol.

Alternative names and synonyms associated with Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)

• protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog (prkar2b.S) antibody
• protein kinase cAMP-dependent type II regulatory subunit beta (PRKAR2B) antibody
• protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B) antibody
• protein kinase cAMP-dependent type II regulatory subunit beta (prkar2b) antibody
• protein kinase, cAMP dependent regulatory, type II beta (Prkar2b) antibody
• Show all gene names
• protein kinase cAMP-dependent type 2 regulatory subunit beta (Prkar2b) antibody

• AI451071 antibody
• AW061005 antibody
• MGC83177 antibody
• Pkarb2 antibody
• PKARIIbeta antibody
• Show all synonym aliases
• PRKAR2 antibody
• PRKAR2B antibody
• RATDNA antibody
• RII(beta) antibody
• RII-BETA antibody

Protein level used designations for PRKAR2B

protein kinase, cAMP-dependent, regulatory, type II, beta , cAMP-dependent protein kinase, regulatory subunit beta 2 , cAMP-dependent protein kinase type II-beta regulatory subunit-like , protein kinase, cAMP dependent regulatory, type II beta , cAMP-dependent protein kinase type II-beta regulatory subunit , Type II beta regulatory subunit of cAMP-dependent protein kinase , H_RG363E19.2 , WUGSC:H_RG363E19.2 , cAMP-dependent protein kinase type II-beta regulatory chain