Sonic Hedgehog ELISA Kits
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Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
1
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
1
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
1
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog ELISA Kit (SHH) ELISA Kit
Sonic Hedgehog (SHH) Antigen Profile
Protein Summary
This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved\; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities. Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly.
Alternative names and synonyms associated with Sonic Hedgehog (SHH)
- sonic hedgehog (SHH) antibody
- sonic hedgehog (Shh) antibody
- sonic hedgehog a (shha) antibody
- sonic hedgehog L homeolog (shh.L) antibody
- sonic hedgehog (shh) antibody
- sonic hedgehog protein A (shh) antibody
- sonic hedgehog b (shhb) antibody
- 9530036O11Rik antibody
- Dsh antibody
- fc83d08 antibody
- hedgehog antibody
- Hhg1 antibody
- HLP3 antibody
- HPE3 antibody
- Hx antibody
- Hxl3 antibody
- M100081 antibody
- MCOPCB5 antibody
- SHH antibody
- SMMCI antibody
- syu antibody
- TPT antibody
- TPTPS antibody
- twh antibody
- twhh antibody
- vhh-1 antibody
- vhh1 antibody
- wu:fc83d08 antibody
- Xhh antibody
- xshh antibody
Protein level used designations for Sonic Hedgehog (SHH) ELISA Kits
sonic hedgehog homolog , sonic hedgehog protein , HHG-1 , hemimelic extra toes , short digits , sonic hedgehog protein A , sonic-you , VHH-1 , X-SHH , morphogen , sonic hedgehog , sonic hedgehog protein B , tiggy winkle hedge hog , tiggy winkle hedgehog , tiggy-winkle hedgehog protein
| GENE ID | SPECIES |
|---|---|
| 6469 | Homo sapiens |
| 20423 | Mus musculus |
| 29499 | Rattus norvegicus |
| 30269 | Danio rerio |
| 398047 | Xenopus laevis |
| 446055 | Takifugu rubripes |
| 100049186 | Oryzias latipes |
| 100136227 | Oncorhynchus mykiss |
| 100169727 | Felis catus |
| 100352774 | Oryctolagus cuniculus |
| 100505407 | Sus scrofa |
| 395615 | Gallus gallus |
| 608860 | Canis lupus familiaris |
| 286821 | Bos taurus |
| 30444 | Danio rerio |
| 100732014 | Cavia porcellus |
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