Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The active form of the protein encoded by this gene consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. Alternative splicing of this gene results in multiple transcript variants.
Alternative names and synonyms associated with Relaxin 2 (RLN2)
relaxin 2 (RLN2) antibody
insulin-like 3 (Leydig cell) (insl3) antibody
bA12D24.1.1 antibody
bA12D24.1.2 antibody
H2 antibody
H2-RLX antibody
RFLX antibody
rln2 antibody
rln3c antibody
rlx3c antibody
RLXH2 antibody
si:rp71-39b20.5 antibody
Protein level used designations for Relaxin 2 Proteins (RLN2)
H2-preprorelaxin
, prorelaxin H2
, relaxin, ovarian, of pregnancy
, relaxin 2
, relaxin 3-like protein c
, relaxin 3c
, relaxin family locus X
, rlnc
