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the ability of insulin to increase the appearance of Rip11 at the cell surface involves an inhibition of Rip11 internalisation from the plasma membrane
The results of this study suggest a requirement for Rab11Fip5, and presumably Rab11, during Hippocampal Long-Term Depression.
Delivery of Rab11-containing membrane stores effects broad and functional pseudopods during FcgammaR-mediated phagocytosis in mutant cultures of kinesin 5B-expressing cells.
Rip11 is a Rab11- and AS160-RabGAP-binding protein required for insulin-stimulatd glucose uptake in adipocytes.
Study shows that both Rab11 and its effector Rip11 participate in insulin granule exocytosis and that Rip11, as a substrate of PKA, regulates the potentiation of exocytosis by cAMP in pancreatic beta-cells.
FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase.
FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells.
These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland.
These data therefore show that (i) Rab11a regulates cell surface abundance of both GLUT4 and FAT/CD36.
analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ).
Rip11/FIP5-kinesin-II complex plays a key role in the routing of internalized receptors through the perinuclear recycling endosomes.
Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane (By similarity).
rab11 family-interacting protein 5
, rab11-interacting protein Rip11
, RAB11 family interacting protein 5 (class I)
, gamma-SNAP-associated factor 1
, phosphoprotein pp75