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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms\; however, the full length nature of one variant has not been determined.
, transcription factor Tbx3
, T-box 3 protein
, T-box 3 (ulnar mammary syndrome)
, T-box transcription factor TBX3-like
, t-box transcription factor TBX3-like
, T-box protein 3
, T-box transcription factor TBX3
, bladder cancer related protein XHL
, T-Box protein 3