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Human CEBPB Protein expressed in Wheat germ - ABIN1349085
Sasaki, Hashimoto, Sawa, Amaya: Tumor necrosis factor-alpha induces expression of C/EBP-beta in primary afferent neurons following nerve injury. in Neuroscience 2014
Nr1d1/Rev-erbalpha (show NR1D1 Proteins) has a direct role in circadian clock regulation of autophagy, which also involves Cebpb/(C/ebpbeta) indirectly in zebrafish
We found that quercetin reduces the promoter activity of apoB (show APOB Proteins), driven by the enforced expression of C/EBPb.
Chromatin immunoprecipitation analysis revealed that C/EBPbeta2 binds to multiple sites at the 5' promoter/regulatory region, introns, and the 3' untranslated region of the IGF-II gene.
C/EBPbeta contributes to all-trans retinoic acid-induced activation of NEAT1 during acute promyelocytic leukemia (show PML Proteins) cell differentiation.
Palmitate can induce lipid accumulation in HepG2 cells by activating C/EBPbeta-mediated G0S2 (show G0S2 Proteins) expression.
Anti-tumor effect of Rg3, which is mediated by inhibition of C/EBPbeta/NF-kappaB (show NFKB1 Proteins) signaling.
C/EBPbeta upregulation promoted tumor cell invasion in an MMP3 (show MMP3 Proteins)-dependent manner in vitro and was associated with metastatic status in colorectal cancer
findings support the hypothesis that maternal diabetes-induced ER stress increases CHOP (show DDIT3 Proteins) expression which represses PGC-1alpha through suppressing the C/EBPbeta transcriptional activity, subsequently induces mitochondrial dysfunction and ultimately results in NTDs
Studies indicate that CCAAT enhancer binding protein beta (C/EBPB)-transcription factor CITED4 (CITED4 (show CITED4 Proteins)) signaling is a pathway in cardioprotection mediating benefits of exercise in heart.
C/EBP beta LAP isoform expression was increased and LIP/TNFAIP3 (show TNFAIP3 Proteins)/TNIP1 (show TNIP1 Proteins) expression was decreased in systemic lupus erythematosus (SLE) patients. LAP expression was positively correlated with SLE disease activity; TNFAIP3 (show TNFAIP3 Proteins) and TNIP1 (show TNIP1 Proteins) expression was negatively correlated with SLE disease activity.
Overexpression of C/EBPbeta-1 increases transformation, upregulates expression of the cancer stem cell marker ALDH1A1 (show ALDH1A1 Proteins), and leads to chemoresistance.
Elevated expression of CEBPB were associated with a decreased risk of hepatocellular carcinoma.
C/EBPbeta overexpression or knockdown did not change the levels of IL-1beta (show IL1B Proteins)-induced SOCS1 (show SOCS1 Proteins). SOCS1 (show SOCS1 Proteins) regulated the levels of C/EBPbeta mRNA by ubiquitination of C/EBPbeta as well as transcriptional regulation in human chondrocytes.
LCoR (show Lcor Proteins) negatively regulates early adipogenesis by repressing C/EBP beta transcriptional activity and add LCoR (show Lcor Proteins) to the growing list of transcriptional corepressors of adipogenesis.
results support a stimulatory effect of Pb on adipogenesis which involves ERK (show EPHB2 Proteins) activation and C/EBPbeta upregulation prior to PPARgamma (show PPARG Proteins) and adipogenesis activation.
Purple sweet potato colour, a class of naturally occurring anthocyanins, exhibited beneficial effects on hepatic steatosis, which were associated with blocking Src (show SRC Proteins) and C/EBPbeta activation.
Thus, this study identifies BCL11B as a novel regulator of adipogenesis, which works, at least in part, by stimulating C/EBPbeta activity and suppressing the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.
Study shows that alpha melanocyte stimulating hormone (show POMC Proteins) and forkhead box C2 protein promote fatty acid oxidation through C/EBPbeta negative transcription in mice adipose tissue.
The results indicated that miR-16 (show GDE1 Proteins) was transactivated by C/EBP-beta resulting in aggravated Ischemia-reperfusion induced acute kidney injury and that urinary miR-16 (show GDE1 Proteins) may serve as a potential biomarker for acute kidney injury.
These results suggest that C/EBPbeta is an endogenous initiator of neuropathic pain and could be a potential target for the prevention and treatment of this disorder.
We found that C/EBPbeta is phosphorylated by CK2 (show CSNK2A1 Proteins) under AMPK (show PRKAA1 Proteins) suppression and ER stress, which are important from the viewpoint of the worsening pathological condition of type 2 diabetes, such as decreased insulin (show INS Proteins) secretion and apoptosis of pancreatic beta cells.
the extracts dramatically attenuated the levels of adipogenic transcriptional factors, including CCAAT enhancer-binding protein alpha (C/EBPa (show CEBPA Proteins)), CCAAT enhancer-binding protein beta (C/EBPb), and gamma receptors by peroxisome proliferators (PPARg (show PPARG Proteins)), during adipogenesis
Expression of the SENP2 (show SENP2 Proteins) gene was suppressed by theobromine. In vivo knockdown studies showed that AR1 (show TCF20 Proteins) knockdown in mice attenuated the anti-adipogenic effects of theobromine in younger mice. Theobromine suppresses adipocyte differentiation and induced C/EBPbeta degradation by increasing its sumoylation.
C/EBP-beta plays a vital role in regulating GPR120 transcription.
The expression of porcine Prdx6 (show PRDX6 Proteins) gene is up-regulated by C/EBPbeta and CREB (show CREB1 Proteins).
Results show that expression changes of IGF1 (show IGF1 Proteins) genes were associated with C/EBP (show CEBPA Proteins) b expression during embryonic and postnatal development in porcine liver.
FoxO1 (show FOXO1 Proteins) and C/EBPb regulate preadipocyte adipogenesis possibly through C/EBPb-> FoxO1 (show FOXO1 Proteins)-> C/EBPb feedback regulatory loop and FoxO1 (show FOXO1 Proteins)-C/EBPb protein complex.
the pig GPD1 (show GPD1 Proteins) gene is regulated negatively by C/EBP beta in cultured kidney cells
GATA-4 (show GATA4 Proteins) and C/EBPbeta are both required for FSH (show BRD2 Proteins) +/- IGF-I (show IGF1 Proteins) stimulation of the porcine steroidogenic acute regulatory protein (show STAR Proteins) gene promoter in homologous granulosa cell cultures.
The differential expression of specific CEBPA (show CEBPA Proteins)/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
SREBP1a activated while C/EBP (show CEBPA Proteins) factors downregulated the activity of the SCD1 (show SCD Proteins) promoter.
These results indicate that the C/EBPbeta gene plays an important regulatory role in regulation of the cell cycle regulators and spermatogenesis-related (show SYCE2 Proteins) genes expression and function of bovine SCs (show TWIST1 Proteins).
Suppression of CPT1B (show CPT1B Proteins) and induction of SCD (show SCD Proteins) and CEBPB by supplemental arginine promotes increased adiposity in Angus steers.
Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta and PPAR-gamma (show PPARG Proteins) gene expression in differentiated myoblasts and an increase in GPR43 (show FFAR2 Proteins) gene expression in adipocytes.
Interaction of C/EBP-beta and NF-Y factors constrains activity levels of the nutritionally controlled promoter IA expressing the acetyl-CoA carboxylase-alpha (show ACACA Proteins) gene in cattle.
The role of NF-kappaB (show NFKB1 Proteins) and C/EBP (show CEBPA Proteins) factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.
The 3' terminal end of the first intron of porcine SPP1 (show SPP1 Proteins) harbors a C/EBPbeta binding site and this binding site is negatively affected by the mutant G allele.
2-chloroethyl ethyl sulfide (show SQRDL Proteins) exposure caused a 2.3-fold increase in the activation of C/EBP (show CEBPA Proteins) accompanied with a 45% and 121% increase in the protein level of C/EBP beta and ICAM-1 (show ICAM1 Proteins), respectively, and this effect was counteracted by the antioxidant liposome.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
CCAAT/enhancer binding protein (C/EBP), beta
, CCAAT/enhancer-binding beta protein b
, CCAAT/enhancer-binding protein beta
, CCAAT/enhancer binding protein beta
, interleukin 6-dependent DNA-binding protein
, liver-enriched transcriptional activator protein
, nuclear factor NF-IL6
, nuclear factor of interleukin 6
, transcription factor 5
, C/EBP BETA
, interleukin-6-dependent-binding protein
, liver-enriched transcriptional activator
, nuclear protein Il6
, C/EBP beta
, c/EBP-related protein 2
, liver activating protein (LAP)
, nuclear factor-IL6
, silencer factor B
, c/EBP beta
, CCAAT box/enhancer binding protein beta
, CCR protein
, transcription factor NF-M