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The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.
prostaglandin E synthase 2
, microsomal prostaglandin E synthase 2
, prostaglandin E synthase 2-like
, GATE-binding factor 1
, gamma-interferon-activated transcriptional element-binding factor 1
, membrane-associated prostaglandin E synthase 2
, microsomal prostaglandin E synthase-2