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Browse our anti-CNOT2 (CNOT2) Antibodies

Full name:: anti-CCR4-NOT Transcription Complex, Subunit 2 Antibodies (CNOT2)

On www.antibodies-online.com are 125 CCR4-NOT Transcription Complex, Subunit 2 (CNOT2) Antibodies from 18 different suppliers available. Additionally we are shipping CNOT2 Proteins (5) and CNOT2 Kits (3) and many more products for this protein. A total of 137 CNOT2 products are currently listed.

Synonyms:: 2600016M12Rik, 2810470K03Rik, AA537049, AA959607, AW557563, C79650, cdc36, cnot2, not2, NOT2H

list all antibodies	Gene Name	GeneID	UniProt
	CNOT2	4848	Q9NZN8
	CNOT2	72068	Q8C5L3
	CNOT2	299805
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Most Popular Reactivities for anti-CNOT2 (CNOT2) Antibodies

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anti-Human CNOT2 Antibodies:

anti-Mouse (Murine) CNOT2 Antibodies:

anti-Rat (Rattus) CNOT2 Antibodies:

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Relevant Pathways for anti-CNOT2 Antibodies

Stem Cell Maintenance

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More Antibodies against CNOT2 Interaction Partners

Human CCR4-NOT Transcription Complex, Subunit 2 (CNOT2) interaction partners

Increased expression of MHC II genes after knock-down or knock-out of either CNOT1, CNOT2, or CNOT3 subunit was seen in a variety of cell systems and also in naive macrophages from CNOT3 conditional knock-out mice.
CNOT2 promotes proliferation and angiogenesis via VEGF signaling in MDA-MB-231 breast cancer cells.
ERG is recruited to mRNAs via interaction with the RNA-binding protein RBPMS, and it promotes mRNA decay by binding CNOT2, a component of the CCR4-NOT deadenylation complex.
The CNOT2-CNOT3 heterodimer is stabilized and tightly anchored to the surface of CNOT1 through an unexpected intertwined arrangement of peptide regions lacking defined secondary structure.
Cnot1, Cnot2, and Cnot3 represent a novel component of the core self-renewal and pluripotency circuitry conserved in mouse and human ESCs.
human CNOT2 is important for maintaining the deadenylase activity and structural integrity of the CCR4-NOT complex, thereby affecting cell viability.
This study shows that SMRT/NCoR-HDAC3 complex is a cofactor of CNOT2-mediated repression and suggests that transcriptional regulation by the Ccr4-Not complex involves regulation of chromatin modification.
major repression function of CNOT2 is localized in a specialized protein motif, the Not-Box
These findings suggest that CDK11 may contribute to apoptosis by regulating the activity of NOT2 independent of its kinase activity.

Mouse (Murine) CCR4-NOT Transcription Complex, Subunit 2 (CNOT2) interaction partners

These data have uncovered a novel role of core components of the Ccr4-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.
Cnot1, Cnot2, and Cnot3 represent a novel component of the core self-renewal and pluripotency circuitry conserved in mouse and human ESCs.

CNOT2 Antigen Profile

Antigen Summary

This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with CNOT2

CCR4-NOT transcription complex subunit 2 (CNOT2) antibody
CCR4-NOT transcription complex, subunit 2 (Cnot2) antibody
CCR4-NOT transcription complex subunit 2 S homeolog (cnot2.S) antibody
CCR4-NOT transcription complex, subunit 2 (cnot2) antibody
CCR4-NOT transcription complex subunit 2 (cnot2) antibody
CCR4-NOT transcription complex subunit 2 (Cnot2) antibody

2600016M12Rik antibody
2810470K03Rik antibody
AA537049 antibody
AA959607 antibody
AW557563 antibody
C79650 antibody
cdc36 antibody
cnot2 antibody
not2 antibody
NOT2H antibody

Protein level used designations for CNOT2

CCR4-NOT transcription complex subunit 2 , CCR4-associated factor 2 , negative regulator of transcription 2 , CCR4-NOT transcription complex, subunit 2 , CCR4-NOT transcription complex subunit 2-like

GENE ID	SPECIES
4848	Homo sapiens
72068	Mus musculus
299805	Rattus norvegicus
417851	Gallus gallus
443622	Xenopus laevis
474446	Canis lupus familiaris
533945	Bos taurus
100037372	Danio rerio
100127821	Xenopus (Silurana) tropicalis
100173614	Pongo abelii
100398024	Callithrix jacchus
100062938	Equus caballus
100153354	Sus scrofa
100718705	Cavia porcellus
100342367	Oryctolagus cuniculus
101685085	Mustela putorius furo
101122772	Ovis aries musimon

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