Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Data suggests that NRIP1 is overexpressed both in skin and PBMCs of psoriasis patients and may be involved in the abnormal proliferation and apoptosis of keratinocytes.
In skeletal muscle, imposed rest increased NRIP1 expression by 80%, and strength training increased expression by 25% compared to baseline. Following rest, NRIP1 expression became sensitive to insulin (show INS Proteins) stimulation. After re-training, NRIP1 expression decreased. Interactome analysis showed significant proximity of NRIP1 interacting partners to the obesity network/module.
Taken together, these results provide new insights into the mechanism of action of LCoR (show Lcor Proteins) and RIP140 and highlight their strong interplay for the control of gene expression and cell proliferation in breast cancer cells.
Study found low expression level of RIP140 in tumor-associated macrophages (TAM (show CCNA1 Proteins)) of hepatocellular carcinoma (HCC (show FAM126A Proteins)) tissues and demonstrated that RIP140 expression in plays a role in the growth of hepatoma cells.
results indicated that there was a significant association between migraine and gene-gene interaction among the CYP19A1 (show CYP19A1 Proteins), FSHR (show FSHR Proteins), ESR1 (show ESR1 Proteins) and NRIP1.
Data indicate that nuclear receptor interacting protein 1 (NRIP1) is elevated in tumors compared to cancer adjacent normal tissue.
NOP14 (show Nop14 Proteins) suppresses breast cancer progression by inhibiting NRIP1/Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway.
NRIP1 contributes to the mitochondrial dysfunction observed in DS. Furthermore, they suggest that the NRIP1-PGC-1alpha axe might represent a potential therapeutic target for restoring altered mitochondrial function in DS.
RIP140 gene has been shown to be involved in the regulation of energy expenditure, in mammary gland development and intestinal homeostasis as well as in behavior and cognition
Downregulation of RIP140 promoted the tumorigenicity of HCC (show FAM126A Proteins) cells in vitro.
Up-regulation of RIP140 promotes glucolipotoxicity-induced damage in pancreatic beta cells.
RIP140 is a co-repressor of HSF1 (show HSF1 Proteins), and it regulates neuronal stress response.
It is able to modulate the transcription of certain genes involved in AD pathology, such as b-APP (show APP Proteins) cleaving enzyme (BACE1 (show BACE Proteins)) and GSK3. Consequently, we found that RIP140 overexpression reduced the generation of Ab in a neuroblastoma (show ARHGEF16 Proteins) cell line by decreasing the transcription of b-APP (show APP Proteins) cleaving enzyme via a PPARge dependent mechanism.
These data indicate that dominant NRIP1 mutations can cause kidney and urinary tract by interference with retinoic acid transcriptional signaling, shedding light on the well documented association between abnormal vitamin A levels and renal malformations in humans, and suggest a possible gene-environment pathomechanism in this disease
RIP140 has a unique role in the acute effect of beta-3 adrenergic receptor (show ADRB3 Proteins) activation.
depletion of receptor-interacting protein 140 could significantly alleviate the inhibitory effects of estrogen on osteoclasts formation and bone resorption activity.
RIP140 protects LSD1 (show KDM1A Proteins)'s catalytic domain and antagonizes its Jade-2 (show PHF15 Proteins)-mediated ubiquitination and degradation.
Nuclear receptor interacting protein 140 (RIP140) is an identified nuclear receptor corepressor that has been shown to suppress mitochondrial biogenesis in skeletal muscle.
Data show that 7,12-dimethylbenzanthracene (DMBA)-induced carcinogenesis is suppressed in nuclear receptor interacting protein 1 (Nrip1) knockout mice.
Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor.
nuclear receptor interacting protein 1
, nuclear receptor-interacting protein 1-like
, nuclear factor RIP140
, nuclear receptor-interacting protein 1
, receptor interacting protein 140
, receptor-interacting protein 140