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Human Monoclonal CSF2 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899319
Hirst, Hallsworth, Peng, Lee et al.: Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor ... in American journal of respiratory and critical care medicine 2002
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Human Monoclonal CSF2 Primary Antibody for ELISA, WB - ABIN1724740
He, Shumansky, Connett, Anthonisen, Paré, Sandford: Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD. in The European respiratory journal 2008
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Rat (Rattus) Monoclonal CSF2 Primary Antibody for CyTOF, FACS - ABIN4898951
Stojić-Vukanić, Nacka-Aleksić, Pilipović, Vujnović, Blagojević, Kosec, Dimitrijević, Leposavić: Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+ T cells in aged rats. in Immunity & ageing : I & A 2015
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Human Monoclonal CSF2 Primary Antibody for FACS - ABIN4895921
Alisa, Boswell, Pathan, Ayaru, Williams, Behboudi: Human CD4(+) T cells recognize an epitope within alpha-fetoprotein sequence and develop into TGF-beta-producing CD4(+) T cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
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Human Polyclonal CSF2 Primary Antibody for FACS, IF - ABIN654647
Stone, Vanderman, Willey, Long, Register, Shively, Stehle, Loeser, Ferguson: Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2015
In a subset of patients who received GM-CSF, circulating myeloid-derived suppressor cells (MDSC), and anti-GM-CSF-neutralizing antibodies (Nabs) were also modulated. The majority of patients developed anti-GM-CSF Nabs, which correlated with improved RFS and OS
this study shows that cortisol inhibits CSF2 via DNA methylation (show HELLS Antibodies) and inhibits invasion in first-trimester trophoblast cells
Upregulation of GM-CSF and M-CSF (show CSF1 Antibodies) production by endothelial cells, an effect that appears to be mediated by NF-kappaB (show NFKB1 Antibodies) and to be independent of IL-1 (show IL1A Antibodies), may be an additional mechanism through which IL-33 (show IL33 Antibodies) contributes to inflammatory activation of the vessel wall.
Oral and periodontal innate immunity is affected by HIV viremia and ART. GCF (show GUCY2F Antibodies) IL-8 (show IL8 Antibodies), G-CSF (show CSF3 Antibodies), as well as serum IL-8 (show IL8 Antibodies), MCP-1 (show CCL2 Antibodies) and GM-CSF may be useful biomarkers for the detection of disease presence and/or its severity due to HIV infection and ART use.
Data suggest that the intratumoral GM-CSF expression, as a potentially independent prognostic biomarker for recurrence, might improve conventional clinical and pathologic analysis to refine outcome prediction for clinically localized clear-cell renal cell carcinoma (show MOK Antibodies) (ccRCC) patients after surgery.
High GM-CSF expression is associated with breast Cancer.
In gastric cancer (GC), tumour-derived GM-CSF activated neutrophils and induced neutrophil PD-L1 (show CD274 Antibodies) expression via Janus kinase (JAK (show JAK3 Antibodies))-signal transducer and activator of transcription 3 (STAT3 (show STAT3 Antibodies)) signalling pathway. The activated PD-L1 (show CD274 Antibodies)(+) neutrophils effectively suppressed normal T-cell immunity in vitro and contributed to the growth and progression of human GC in vivo.
The IL-3 (show IL-3 Antibodies)/ GM-CSF effected on the myofibroblastic differentiation of human adipose derive stromal cells (hASCs) as well as it did on human dermal fibroblasts (HDFs).
Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 (show IL5 Antibodies) and GM-CSF.
Data suggest that the methylotrophic yeast Pichia pastoris is an effective recombinant host for heterologous granulocyte-macrophage colony-stimulating factor (rhGM-CSF) production.
TRAF6 (show TRAF6 Antibodies) is also required for GM-CSF-induced ubiquitination and activation of Akt (show AKT1 Antibodies).
CSF2 stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (show MAPK1 Antibodies)-dependent MTOR (show FRAP1 Antibodies) signal transduction cascades.
results show T cell production of GM-CSF contributes to control of M. tuberculosis infection in the absence of other sources of GM-CSF, that multiple T cell subsets make GM-CSF in the lung over the course of infection and that GM-CSF can act directly on infected macrophages through a pathway requiring PPARgamma (show PPARG Antibodies) to limit bacterial growth
In conclusion, our study confirms the pathogenic role of GM-CSF in colitis-associated colorectal cancer development. GM-CSF favors tumor-permissive microenvironment by inducing MDSC generation and recruiting them into colonic tissues.
these data demonstrate that GM-CSF levels during radiotherapy can be used as a prognostic biomarker for lung and esophageal cancer
this study demonstrates that epithelial-derived GM-CSF is a critical early signal during allergic sensitization to cockroach allergen
These impaired macrophage functions in leukemic mice were significantly corrected by IL-3 (show IL-3 Antibodies) and GM-CSF treatment indicating the therapeutic benefit of these two cytokines in leukemia.
Both IL-6 (show IL6 Antibodies) protein production and transcript levels were downregulated by RA in respiratory tract epithelial cells (LETs) , but upregulated in macrophages (MACs). RA also increased transcript levels of MCP-1 (show CPT1B Antibodies), GMCSF, and IL-10 (show IL10 Antibodies) in MACs, but not in LETs. Conversely, when LETs, but not MACs, were exposed to RA
T-GM-CSF and -IL-3 (show IL-3 Antibodies) significantly, and reciprocally, blunted receptor binding and myeloid progenitor cell proliferation activity of both FL-GM-CSF and -IL-3 (show IL-3 Antibodies) in vitro and in vivo
Results indicate GM-CSF as both a key contributor to the pathogenesis of MI and a potential therapeutic target.
GM-CSF is required for the normal balance of leukocyte subsets, including granulocytes, B cells, and naive vs. effector T cells. There was an approximately 3-fold increase in the percentages of granulocytes in Csf2-/- PBMCs. The presence of maximal experimental autoimmune encephalomyelitis in the complete absence of GM-CSF revealed that GM-CSF is not an obligate effector molecule in all forms of EAE.
It was concluded that CSF2 can act as a developmental programming agent but alone is not able to abolish the adverse effects of in vitro production on fetal characteristics.
These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 (show CXCL10 Antibodies) and GM-CSF gene transcription.
Data suggest exposure to maternal CSF2 from D5-D7 of development is fundamentally different for female/male blastocysts with respect to embryo elongation, characteristics of transcriptome/methylome, and endometrial interferon tau secretion at D15 (show MRPL16 Antibodies).
The increase in calving rate caused by CSF2 treatment involves, in part, more extensive development of extraembryonic membranes and capacity of the conceptus to secrete IFNT2 at day 15 of pregnancy.
immunolocalization studies confirmed the presence of granulocyte-macrophage colony stimulating factor(GM-CSF) in the germ cell line in bovine and human testes and addition of GM-CSF enhances several parameters of sperm motility
the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 (show PTGS2 Antibodies) and GM-CSF during the peri (show PLIN1 Antibodies)-attachment period in the cow.
CSF2 affect embryonic development and enhance embryo competence for posttransfer survival.
Data indicate that differentially expressed IL-17 (show IL17A Antibodies), IL-22 (show IL22 Antibodies), and IL-23 (show IL23A Antibodies) levels are associated with K-ras (show HRAS Antibodies) in a stage-specific fashion along colorectal cancer progression and an association was established between mutant K-ras (show HRAS Antibodies) and GM-CSF and IFN-gamma (show IFNG Antibodies).
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
, granulocyte-macrophage colony-stimulating factor
, colony stimulating factor 2 (granulocyte-macrophage)
, colony-stimulating factor
, granulocyte-macrophage colony stimulating factor 2
, put. GM-CSF
, granulate-macrophage stimulating factor
, granulocyte-macrophage stimulation factor