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anti-Human EPO Antibodies:
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Human Polyclonal EPO Primary Antibody for IF (p), IHC (p) - ABIN679718
DeNiro, Al-Mohanna: Nuclear factor kappa-B signaling is integral to ocular neovascularization in ischemia-independent microenvironment. in PLoS ONE 2014
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Human Polyclonal EPO Primary Antibody for ELISA, WB - ABIN153425
Ryou, Choudhury, Li, Winters, Yuan, Liu, Yang: Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress. in Neuroscience 2015
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Human Monoclonal EPO Primary Antibody for WB - ABIN2473499
Gladun: [Theoretical problems of legal regulations of the reorganization of public health in the USSR]. in Sovetskoe zdravookhranenie / Ministerstvo zdravookhranenii?a SSSR 1991
Show all 4 Pubmed References
Human Monoclonal EPO Primary Antibody for ICC, ELISA - ABIN969109
Hirschler-Laszkiewicz, Tong, Conrad, Zhang, Flint, Barber, Barber, Cheung, Miller: TRPC3 activation by erythropoietin is modulated by TRPC6. in The Journal of biological chemistry 2009
Human Monoclonal EPO Primary Antibody for ELISA, WB - ABIN515362
Wang, Dou, Lü, Liu: Immuno-magnetic beads-based extraction-capillary zone electrophoresis-deep UV laser-induced fluorescence analysis of erythropoietin. in Journal of chromatography. A 2012
Data show that erythropoietin (EPO) mRNA was upregulated in the lung, from the metamorphic climax (stage 60) onward.
the implication of alpha-7-nAChR (show CHRNA4 Antibodies)-JAK-2 (show JAK2 Antibodies)/STAT-3 (show STAT3 Antibodies)-Nrf-2 (show GABPA Antibodies) signaling cascade in the radiomitigative potential of EPO against ARS (show SLURP1 Antibodies)
Pro-inflammatory proteins S100A9 (show S100A9 Antibodies) and tumor necrosis factor-alpha (show TNF Antibodies) suppress erythropoietin elaboration in myelodysplastic syndromes
Results suggest an interplay of the production and action of hydrogen sulfide (show SQRDL Antibodies) during hypoxia with subsequent erythropoietin production regulated by HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha (show EPAS1 Antibodies).
EPO levels in the coronary artery disease (CAD (show CAD Antibodies)) group were higher than those in the non-CAD (show CAD Antibodies) group. The correlation between red cell distribution width and EPO levels was statistically significant among CAD (show CAD Antibodies) patients.
CD133(+) cells contributed to the local production of erythropoietin, as observed by detection of circulating human erythropoietin. CD133(+) cells appear therefore an effective source for cell repair, able to restore renal functions, including erythropoietin release, and to limit long term maldifferentiation and fibrosis.
Circulating anti-EPO are detected in a significant proportion of treatment-naive HCV-infected patients and are independently associated with anemia, suggesting a further implication of autoimmunity in the pathophysiology of HCV-related anemia.
the T allele of SNP rs60684937 located at 67,419,130 bp on chromosome 17 was associated with increased plasma EPO and a relatively increased expression of a non-coding transcript of PRKAR1A (show PRKAR1A Antibodies) in sickle cell disease patients
study describes a gain-of-function variant in EPO in an extended kindred with familial erythrocytosis, including 10 affected family members in four generations; this mutation, a single-nucleotide deletion (c.32delG), introduces a frameshift in exon 2
Here, using zebrafish, murine, and human models, the authors show that erythropoietin (EPO) signaling, together with the GATA1 (show GATA1 Antibodies) transcriptional target, AKAP10 (show AKAP10 Antibodies), regulates heme biosynthesis during erythropoiesis at the outer mitochondrial membrane.
Reduction in central venous blood pressure prompts an increase in plasma EPO concentration independent of hemoconcentration and hence suggests CVP per se as an acute regulator of EPO synthesis
Compared to wild type (WT) animals, Epo-TAg(h) female mice exhibited higher ventilation in hypoxia. However, when data were separated into luteal and follicular phases of the estrous cycle, basal ventilation and hypoxic ventilation were not different in both mice strains. Experiments with mifepristone (progesterone receptor (show PGR Antibodies) antagonist) suggest that this effect is independent from the respiratory effects of progesterone.
this study revealed a new mechanism wherein EPO alleviates hepatic steatosis by activating autophagy via SIRT1 (show SIRT1 Antibodies)-dependent deacetylation of LC3 (show MAP1LC3A Antibodies).
This study suggests that moderate elevated brain Epo levels provide clinically significant neuroprotection in experimental autoimmune encephalomyelitis without modulation of the immune response making a significant contribution.
The functional role of signal cascades involved in the production of erythropoietin by T cells is determined by the stage of the common adaptation syndrome.
A novel biological pathway has been discovered of soluble biglycan (show BGN Antibodies) inducing HIF-2alpha (show EPAS1 Antibodies) protein stabilization and Epo production presumably in an oxygen-independent manner, ultimately giving rise to secondary polycythemia.
data identify the PHD2 (show EGLN1 Antibodies):HIF-2alpha:EPO axis as a so far unknown regulator of osteohematology by controlling bone homeostasis.
these data provide strong evidence for a role for G-CSF (show CSF3 Antibodies) in the development of ACI after burn injury through suppression of EPO signaling in bone marrow erythroid cells.
Data indicated the possible involvement of Jak2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies)/STAT6 (show STAT6 Antibodies) pathway in the augmentation of EPO on M2 polarization. These results improved the understanding of the immunoregulatory capacity of EPO on macrophages, which might optimize the therapeutic modalities of EPO.
The lack of effect of erythropoietin on hepcidin (show HAMP Antibodies) expression in mask mice can not be explained by changes in erythroferrone synthesis, as splenic erythroferrone content increased after erythropoietin administration in both C57BL/6 and mask mice.
EPO expression in myoblasts and myotubes is increased by hypoxia and exercise
EPO might play a role as a survival factor or as a mitogen in developing cartilage tissue.
Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass.
A single intramuscular injection of recombinant adeno (show ADORA2A Antibodies)-associated virus carrying mutant Epo (R76E) preserves retinal ganglion cells and visual function in glaucomatous mice.
The zebrafish epo cDNA was cloned and the expression of zepo mRNA was mainly in the heart and liver.
characterization of zebrafish epo and epor (show EPOR Antibodies) demonstrates the conservation of an ancient program that ensures proper red blood cell numbers during normal homeostasis and under hypoxic conditions
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.