Browse our anti-IL-4 (IL4) Antibodies

Full name:: anti-Interleukin 4 Antibodies (IL4)

On www.antibodies-online.com are 780 Interleukin 4 (IL4) Antibodies from 40 different suppliers available. Additionally we are shipping IL-4 Kits (301) and IL-4 Proteins (196) and many more products for this protein. A total of 1300 IL-4 products are currently listed.

Synonyms:: BCGF-1, BCGF1, BSF-1, BSF1, Il-4, IL2, IL4, Il4e12

list all antibodies	Gene Name	GeneID	UniProt
	IL4	3565	P05112
	IL4	16189	P07750
	IL4	287287	P20096
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Most Popular Reactivities for anti-IL-4 (IL4) Antibodies

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anti-Human IL-4 Antibodies:

anti-Mouse (Murine) IL-4 Antibodies:

anti-Rat (Rattus) IL-4 Antibodies:

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Relevant Pathways for anti-IL-4 Antibodies

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Top referenced anti-IL-4 Antibodies

Human Monoclonal IL-4 Primary Antibody for - ABIN1383943 : Stassi, Todaro, Zerilli, Ricci-Vitiani, Di Liberto, Patti, Florena, Di Gaudio, Di Gesù, De Maria: Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10. in Cancer research 2003 (PubMed)
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Human Polyclonal IL-4 Primary Antibody for WB - ABIN3042695 : Presti, DOrazio, Labra, La Ferla, Mezzasalma, Bizzaro, Giardina, Michelotti, Tursi, Vassallo, Di Gennaro: Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect. in Applied microbiology and biotechnology 2015 (PubMed)
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Mouse (Murine) Monoclonal IL-4 Primary Antibody for FACS, Neut - ABIN1177017 : Haak-Frendscho, Brown, Iizawa, Wagner, Czuprynski: Administration of anti-IL-4 monoclonal antibody 11B11 increases the resistance of mice to Listeria monocytogenes infection. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)
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Mouse (Murine) Polyclonal IL-4 Primary Antibody for WB - ABIN3043168 : Wang, Feng, Shi, Hao, Yang, Zhang, Kong: Silencing of miR155 promotes the production of inflammatory mediators in Guillain-Barré syndrome in vitro. in Inflammation 2013 (PubMed)
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Human Polyclonal IL-4 Primary Antibody for IHC (p), WB - ABIN3044141 : Tan, Liu, Yang, Wang, Qin: An inactivated Pseudomonas aeruginosa medicament inhibits airway allergic inflammation and improves epithelial functions. in The journal of physiological sciences : JPS 2012 (PubMed)
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Mouse (Murine) Monoclonal IL-4 Primary Antibody for ELISA - ABIN263080 : Xu, Liu, Fan, Yang, Korner, Fu, Uzonna: Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
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Mouse (Murine) Monoclonal IL-4 Primary Antibody for Neut, ELISA - ABIN2689762 : Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. in Immunological reviews 1992 (PubMed)
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Mouse (Murine) Monoclonal IL-4 Primary Antibody for Neut, ELISA - ABIN1177294 : Litton, Sander, Murphy, OGarra, Abrams: Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B. in Journal of immunological methods 1994 (PubMed)
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Human Monoclonal IL-4 Primary Antibody for ICS, Neut - ABIN1177267 : Chrétien, Van Kimmenade, Pearce, Banchereau, Abrams: Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4. in Journal of immunological methods 1989 (PubMed)
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Rat (Rattus) Monoclonal IL-4 Primary Antibody for BR, Neut - ABIN2689765 : Prigent, Saoudi, Pannetier, Graber, Bonnefoy, Druet, Hirsch: Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4. in The Journal of clinical investigation 1995 (PubMed)
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More Antibodies against IL-4 Interaction Partners

Human Interleukin 4 (IL4) interaction partners

serum antibodies against HP-NAP (show CTNNBL1 Antibodies) represent a state of risk, which is further exacerbated in IL-4 -590 T carriers.
Polymorphisms at IL10 (show IL10 Antibodies) (-1082 G>A), IL4 (-589 C>T), CTLA4 (show CTLA4 Antibodies) (+49A>G), and DAO (show ABP1 Antibodies) (+8956 C>G) genes were studied in 55 cases.
Defective sirtuin-1 (show SIRT1 Antibodies) was found to increase IL-4 expression through acetylation of GATA-3 (show GATA3 Antibodies) in patients with severe asthma compared with healthy controls.
The results confirmed that the IL-4-590C/T polymorphism is correlated with the onset of RA and that carrying the T-allele can significantly increase the risk of rheumatoid arthritis in the Chinese Han population.
the IL-4-590 C>T polymorphism does not influence the development of head and neck cancer.
the present study suggests that IL-4 polymorphisms might play a role in susceptibility to inflammatory bowel disease and its major subtypes in the Iranian population
IL-4R plays an important role in regulating hepatocellular carcinoma (HCC (show FAM126A Antibodies))cell survival and metastasis, and regulates the activity of the JAK1 (show JAK1 Antibodies)/STAT6 (show STAT6 Antibodies) and JNK (show MAPK8 Antibodies)/ERK1/2 signaling pathways. We therefore suggest that IL-4/IL-4R may be a new therapeutic target for HCC (show FAM126A Antibodies)
IL-4 rs2227288 and IL-10 (show IL10 Antibodies) rs1800872 may contribute to an increased risk for virus-induced encephalitis. Through use of direct sequencing, we showed that genotypes of IL-4 rs2227288 and IL-10 (show IL10 Antibodies) rs1800872 may have particular host susceptibility to virus-induced encephalitis. IL-4 rs2227283 and IL-10 (show IL10 Antibodies) rs1800871 have no correlation in with risk of virus-induced encephalitis (both P>0.05)
Interactions among polymorphisms of IFN-gamma (show IFNG Antibodies)+874 AA, IL-2 (show IL2 Antibodies)-330 TT, IL-10 (show IL10 Antibodies)-1082 AA, IL10 (show IL10 Antibodies)--592 AC and IL-4-589 CC/CT significantly influenced the clinical progression of the subjects with hepatitis B virus and/or hepatitis C virus infection.
IL-4 and IL-8 (show IL8 Antibodies) genetic polymorphisms determine susceptibility to chronic Aggregatibacter actinomycetemcomitans periodontitis.

Mouse (Murine) Interleukin 4 (IL4) interaction partners

The VEGFR1 (show FLT1 Antibodies)-mediated signaling suppressed IL-4-induced Arg-1 (show ARG1 Antibodies) expression.
The results obtained in the present study suggest that a signaling pathway mediated by FcRg (show FCER1G Antibodies) or the FcRg (show FCER1G Antibodies)-Syk (show SYK Antibodies) axis is commonly required for innate basophil IL-4 responses under conditions mimicking encounters with allergen sources.
IL-4Delta2 did not compete with IL-4 for IL-4Ralpha binding and did not interfere with the downstream STAT-6 (show STAT6 Antibodies) phosphorylation in T cells.
this study shows that IL4 and IL21 (show IL21 Antibodies) cooperate to induce the high Bcl6 (show BCL6 Antibodies) protein level required for germinal center formation
The complex role of IL-4 in autoimmunity and cholangitis.
The results demonstrate that IL-4 can restore insulin (show INS Antibodies) sensitivity in adipocytes via mechanisms not associated with induced adipogenesis or de novo formation of lipid depots.
Interleukin 4 (IL-4) signaling prevents Chlamydia trachomatis Infection from Inducing upper genital tract (UGT (show SLC35A2 Antibodies)) pathology.
In the lung, surfactant protein A (show GPR153 Antibodies) (SP-A (show SFTPA1 Antibodies)) enhanced interleukin-4 (IL-4)-dependent macrophage proliferation and activation, accelerating parasite clearance and reducing pulmonary injury after infection with a lung-migrating helminth. In the peritoneal cavity and liver, C1q enhancement of type 2 macrophage activation was required for liver repair after bacterial infection.
Data, including data from studies using transgenic mice, suggest that over-expression of IL4 (interleukin 4) in thyroid tissue/cells up-regulates expression of Duox1 (dual oxidase 1), Duoxa1 (dual oxidase maturation factor 1), and Slc26a4 (pendrin) in thyroid tissue/cells; expression of Slc5a5 (sodium-iodide symporter) is down-regulated.
NK cells activated by IL-4 in cooperation with IL-15 (show IL15 Antibodies) exhibit distinctive characteristics with enhanced immunologic cytotoxicity.

Cow (Bovine) Interleukin 4 (IL4) interaction partners

These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma (show IFNG Antibodies) occurring after parturition and an increase in IL-4 production before calving.
IL-4 may play a role in coordinating the adrenal response to inflammatory stress.
T helper (Th) type 2 cell cytokine IL-4 modulates airway contraction by secreting matrix metalloproteinase-1 (show MMP1 Antibodies) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.

Pig (Porcine) Interleukin 4 (IL4) interaction partners

IL-4- and IL-10 (show IL10 Antibodies)-producing invariant NKT (show SLC22A6 Antibodies) cells inhibit the Th1 (show TH1L Antibodies) cell response, but not the Th17 cell response
IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.
There was no significant difference of IL-4 production between fresh and frozen peripheral blood mononuclear cells.
The endothelium and subendothelium of porcine iliac arteries that are transduced with recombinant pig IL-4 are effectively protected from complement-dependent immediate injury after perfusion with human blood.
unlike in humans and mice, porcine IL-4 blocks antibody and IL-6 (show IL6 Antibodies) secretion and suppresses antigen-stimulated proliferation of B cells

Guinea Pig Interleukin 4 (IL4) interaction partners

Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 ratio were significantly lower than those exposed to its low concentration.
IL-4 and STAT6 (show STAT6 Antibodies) are related to the pathogenesis of allergic rhinitis and may be the main factors for eosinophil infiltration in allergic rhinitis.

Horse (Equine) Interleukin 4 (IL4) interaction partners

The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Antibodies) biased, interferon-gamma (show IFNG Antibodies) production is qualitatively similar to adult horses, and regulatory IL-10 (show IL10 Antibodies) production by T cells is mature.
This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 or IL-5 (show IL5 Antibodies).

Rhesus Monkey Interleukin 4 (IL4) interaction partners

Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine genes IL4.
Mycobacterial infections of macaques induce mRNA encoding a variant IL-4 that functions as a growth factor to promote expansion of 4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T effector cells.

IL-4 (IL4) Antigen Profile

Antigen Summary

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with IL-4 (IL4)

interleukin 4 (IL4) antibody
interleukin 4 (Il4) antibody

BCGF-1 antibody
BCGF1 antibody
BSF-1 antibody
BSF1 antibody
Il-4 antibody
IL2 antibody
IL4 antibody
Il4e12 antibody

Protein level used designations for anti-Interleukin 4 (IL4) Antibodies

interleukin 4 , B cell growth factor 1 , B_cell stimulatory factor 1 , binetrakin , interleukin-4 , lymphocyte stimulatory factor 1 , pitrakinra , B-cell IgG differentiation factor , B-cell growth factor 1 , B-cell stimulatory factor 1 , IGG1 induction factor , B-cell IGG differentiation factor , BSF-1 , IL-4 , Lymphocyte stimulatory factor 1

GENE ID	SPECIES
100126747	Papio anubis
3565	Homo sapiens
16189	Mus musculus
287287	Rattus norvegicus
280824	Bos taurus
397225	Sus scrofa
403785	Canis lupus familiaris
100860814	Capra hircus
443327	Ovis aries
416330	Gallus gallus
101801081	Anas platyrhynchos
100720403	Cavia porcellus
100302454	Oryctolagus cuniculus
100034225	Equus caballus
751514	Felis catus
574281	Macaca mulatta
100482473	Ailuropoda melanoleuca
101843742	Mesocricetus auratus
449565	Pan troglodytes
101338293	Tursiops truncatus

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Show all anti-Interleukin 4 (IL4) Antibodies with Pubmed References