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- Target See all DR3/LARD (TNFRSF25) ELISA Kits
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- Binding Specificity
- AA 25-201
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TNFRSF25/DR3
- Brand
- PicoKine™
- Analytical Method
- Quantitative
- Specificity
- Expression system for standard: NSO, Immunogen sequence: Q25-F201
- Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Characteristics
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Tissue Specificity: Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
- Top Product
- Discover our top product TNFRSF25 ELISA Kit
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Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) ELISA Kit
TNFRSF25 Reactivity: Human Colorimetric Sandwich ELISA 0.24 ng/mL - 15 ng/mL Plasma, Serum, Tissue Homogenate
Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) ELISA KitTNFRSF25 Reactivity: Mouse AA 31-199 Colorimetric Sandwich ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) ELISA KitTNFRSF25 Reactivity: Human Colorimetric Sandwich ELISA 312-20000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) ELISA KitTNFRSF25 Reactivity: Human Colorimetric Sandwich ELISA 0.24-15 ng/mL Plasma, Serum, Tissue Homogenate
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- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
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- Target See all DR3/LARD (TNFRSF25) ELISA Kits
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- Alternative Name
- TNFRSF25 (TNFRSF25 Products)
- Background
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Protein Function: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Background: Death receptor 3 (DR3), also known as tumor necrosis factor receptor superfamily member 25 (TNFRSF25), is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
Synonyms: Tumor necrosis factor receptor superfamily member 25,Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,LARD,Protein WSL,Protein WSL-1,TNFRSF25,APO3, DDR3, DR3, TNFRSF12, WSL, WSL1,UNQ455/PRO779,
Full Gene Name: Tumor necrosis factor receptor superfamily member 25
Cellular Localisation: Isoform 1: Cell membrane, Single-pass type I membrane protein. - UniProt
- Q93038
- Pathways
- Apoptosis
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