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Human Polyclonal PNLIPRP2 Primary Antibody for ELISA, WB - ABIN562295
Porterfield, Zhao, Han, Cunningham, Aoki, Von Hoff, Demeure, Pierce, Tiemeyer, Wells: Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis. in Journal of proteome research 2014
The beta5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2
Pancreatic lipase-related protein 2 digests fats in human milk and formula in concert with gastric lipase and carboxyl ester lipase.
BSSL and PLRP2 hydrolyzed triglycerides (TG) to free FA and glycerol.
Pancreatic lipase-related protein-2 (PLRP2) can contribute to dietary fat digestion in human newborns
localization of PLRP2 in endosomes of monocytes
Investigation of the substrate specificity of purified recombinant pancreatic lipase-related protein 2 reveals that its physiological role is digestion of galactolipids, the main plant lipids present in the vegetables which are a part of the human diet.
Patients with chronic calcifying pancreatitis (CCP (show CRYGD Antibodies)) had significantly lower levels of both pancreatic lipase (show PNLIP Antibodies) and PLRP2 than the controls subjects.
Most of the structural and kinetic properties of HPLRP2 were found to be different from those of rat PLRP2
The pancreatic lipase related protein 2 is required for lipid-dependent cytotoxicity mediated by cytotoxic T lymphocytes.
study concluded that pancreatic lipase-related protein 2 is the major colipase (show CLPS Antibodies)-dependent lipase (show LIPG Antibodies) in the pancreas of newborn mice
BSSL and PLRP2 responsible for fat digestion as long as milk is the main food. Milk-borne BSSL is able to compensate for a slower ontogeny of pancreatic BSSL expression in the mouse.
PLRP2 induction by IL-4 (show IL4 Antibodies) in cytotoxic T-lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity are reported.
A pancreatic lipase-related protein 2 mutant with a seven-residue deletion of beta9 loop showed reduced enzyme activity with a larger effect on long acyl chain substrates.
major digestive lipase of pancreas
pancreatic lipase-related protein 2
, pancreatic lipase-related protein 2-like
, cytotoxic T-lymphocyte lipase
, secretory glycoprotein GP-3